Photo by Cindy Keese

Find Family Hotels in Seneca, SC

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Compare Seneca Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Fall fun at the cabin! Convenient to Lake Keowee and Clemson
Welcome to our home!

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

9.2 out of 10, Wonderful, (74)
"Our stay was around when Helene Hurricane came through, Sept 27, 2024. The power was out so the cleaning person wasn't able to finish their task prior to our check in. However, there were clean linens and towels in the basement next to the washing machine. We also had trash bags, clean dishes and running water but no power. The cabin was nicely located in Seneca which wasn't far from the university. The cabin was also easy to find. "
Fall fun at the cabin! Convenient to Lake Keowee and Clemson
Best Western Seneca-Clemson
Exterior

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (563)
"Killed one large roach. Needs better outside lighting. Everything else was great"
The price is SAR 348
SAR 383 total
includes taxes & fees
4 Jan - 5 January 2025
Best Western Seneca-Clemson
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
Private covered slip dock with power and lights

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

10.0 out of 10, Exceptional, (215)
"What a great weekend! My son and I met old friends (Dad & 3 sons) for our annual Clemson trip. The house was perfect for us! Plenty of room and the boys loved the pool table. Everything was top notch! Thank you so much!"
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
Quality Inn Seneca US-123
Room

Quality Inn Seneca US-123

2.5 star property
8.0 out of 10, Very Good, (557)
"Very good stay! The front desk service is fantastic!"
The price is SAR 331
SAR 402 total
includes taxes & fees
19 Jan - 20 January 2025
Quality Inn Seneca US-123
Hampton Inn & Suites Seneca-Clemson Area
Exterior

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (569)
"Staff was very friendly. Quiet and clean hotel. "
The price is SAR 438
SAR 482 total
includes taxes & fees
1 Jan - 2 January 2025
Hampton Inn & Suites Seneca-Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
Exterior

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (653)
"Rooms need new carpet & painting. Pricing reflects the physical condition of the rooms. Front desk staff were exceptionally nice & courteous."
The price is SAR 268
SAR 295 total
includes taxes & fees
19 Jan - 20 January 2025
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Seneca like for family-friendly vacations?
The welcoming destination of Seneca is a good choice if you’ve been considering a getaway with your kids. The boating, lake views, and sporting events are just some of the things that make this the perfect spot for family trips. Fly into Greenville-Spartanburg Intl. Airport (GSP), which is located 44.1 mi (71 km) from the city center.
What's the best accommodation for families in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it’s a top choice on Expedia for families.
How many family-friendly hotels should I expect to find in Seneca?
Expedia has 6 family-friendly hotels and other accommodations in Seneca.
When's the best time to book a family-friendly vacation in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.
What's there to see and do with your family in Seneca?
While you and your family are vacationing in Seneca, you might want to visit some family-friendly attractions such as Wyndham Plaza and World of Energy. Make sure you have lots of time for activities like The Gauntlet and Oconee County Library Seneca Branch.