Photo by Cindy Keese

Find Family Hotels in Seneca, SC

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Pick from 9 Seneca Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

9.2 out of 10, Wonderful, (73)
"Our stay was around when Helene Hurricane came through, Sept 27, 2024. The power was out so the cleaning person wasn't able to finish their task prior to our check in. However, there were clean linens and towels in the basement next to the washing machine. We also had trash bags, clean dishes and running water but no power. The cabin was nicely located in Seneca which wasn't far from the university. The cabin was also easy to find. "
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (555)
"I don't think there's much unique about the Best Western in Seneca. But It scored very high for me. The room was spacious and very comfortable. The bathroom facilities, including the tub/shower were above average. The included breakfast was great. (I was only sorry that I couldn't partake on both mornings of my stay.) The staff was very friendly and very helpful. The only negative, and it was tiny and eventually resolves by the staff, was that the TV remote in the room was basically...
The price is SAR 319
SAR 351 total
includes taxes & fees
6 Dec - 7 Dec
Best Western Seneca-Clemson

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

10.0 out of 10, Exceptional, (213)
"We loved this house! It was the perfect spot to gather as a family and really spend quality time together. We were there to celebrate our Clemson son’s ring ceremony and my birthday and John and Terri were so kind and had a beautiful cake waiting for us in the fridge! Such a sweet surprise. The pool table was so fun to have and a big hit. And the kitchen was very well supplied with everything we needed to cook any meals. And the back screened in porch was so lovely, for reading, morning coffee,...
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Quality Inn Seneca US-123

2.5 star property
8.0 out of 10, Very Good, (553)
"Nice stay"
The price is SAR 269
SAR 332 total
includes taxes & fees
16 Dec - 17 Dec
Quality Inn Seneca US-123

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (565)
"The rooms were exceptionally clean and breakfast was great every morning! It was such a pleasant experience! "
The price is SAR 455
SAR 501 total
includes taxes & fees
15 Dec - 16 Dec
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (646)
"My stay was very nice. The only thing was the tv was broken in rm 121. No worries, tough, as i was busy with family "
The price is SAR 262
SAR 288 total
includes taxes & fees
12 Dec - 13 Dec
Days Inn by Wyndham Seneca / Clemson Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Seneca like for family-friendly vacations?
The welcoming destination of Seneca is a good choice if you’ve been considering a getaway with your kids. The boating, lake views, and sporting events are just some of the things that make this the perfect spot for family trips. Fly into Greenville-Spartanburg Intl. Airport (GSP), which is located 44.1 mi (71 km) from the city center.
What's the best accommodation for families in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it’s a top choice on Expedia for families.
How many family-friendly hotels should I expect to find in Seneca?
Expedia has 6 family-friendly hotels and other accommodations in Seneca.
When's the best time to book a family-friendly vacation in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.
What's there to see and do with your family in Seneca?
While you and your family are vacationing in Seneca, you might want to visit some family-friendly attractions such as Memorial Stadium and T. Ed Garrison Arena. Make sure you have lots of time for activities like Lake Hartwell State Park and Tugaloo State Park.