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Compare 236 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Baymont by Wyndham Santee
2.5 star property
7.8 out of 10, Good, (1281)
"Convenient. Cheap. Comfortable "
The price is SAR 266
SAR 296 total
includes taxes & fees
24 Sep - 25 Sep
Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee
2.5 star property
9.8 out of 10, Exceptional, (1003)
"Beautiful hotel. Clean. Breakfast buffet was extensive and very tasty. Staff friendly and efficient. Great location, right off I 95. Excellent stay. 💥💥👏👏"
The price is SAR 533
SAR 591 total
includes taxes & fees
29 Sep - 30 Sep
Fairfield Inn & Suites by Marriott Santee
Days Inn by Wyndham St George
2.5 star property
7.2 out of 10, Good, (1004)
"This property has been updated and looks very nice. The room was clean and very pleasant, breakfast was the usual continental offering. Would definitely stay again "
The price is SAR 201
SAR 223 total
includes taxes & fees
20 Oct - 21 Oct
Days Inn by Wyndham St George
Quality Inn & Suites
2.5 star property
6.4 out of 10, (264)
"This place looks abandoned. All the trees are either dead, or cut down. Half of the hotel is boarded up. The rooms are dated, but somewhat clean. The towels though, thats another story. They look as though they have never been washed."
The price is SAR 207
SAR 249 total
includes taxes & fees
6 Oct - 7 Oct
Quality Inn & Suites
Comfort Inn & Suites Santee
2.5 star property
8.0 out of 10, Very Good, (887)
"Vending machine was out of service,"
The price is SAR 372
SAR 413 total
includes taxes & fees
13 Oct - 14 Oct
Comfort Inn & Suites Santee
Tru By Hilton Santee
2.5 star property
9.0 out of 10, Wonderful, (217)
"I have no complaints at all. There was trouble with the internet though, but I think there was an internet connection problem in the whole area. Overall nice, clean hotel and friendly/helpful staff."
The price is SAR 424
SAR 471 total
includes taxes & fees
26 Sep - 27 Sep
Tru By Hilton Santee
Hampton Inn Santee-I-95
2.5 star property
9.6 out of 10, Exceptional, (1004)
"We would definitely stay here again, enroute from FL to MA. Staff and hotel was great. Breakfast was very good and has more options than similar hotels."
The price is SAR 507
SAR 562 total
includes taxes & fees
29 Sep - 30 Sep
Hampton Inn Santee-I-95
Holiday Inn Santee, an IHG Hotel
3.0 star property
8.2 out of 10, Very Good, (769)
"Property was clean and plenty of parking"
The price is SAR 468
SAR 519 total
includes taxes & fees
29 Sep - 30 Sep
Holiday Inn Santee, an IHG Hotel
Travelodge by Wyndham Santee
2.0 star property
7.0 out of 10, Good, (529)
"We stayed here on the way to the Port of Charleston. Beds were comfortable but small as they are doubles and there are 4 of us. Rooms were clean. Check in was fast and easy. Parking is plentiful. There is a pool that is not in service, but we weren’t here for that. The outside is a bit messy/run down."
The price is SAR 225
SAR 250 total
includes taxes & fees
24 Sep - 25 Sep
Travelodge by Wyndham Santee
Best Western Plus Santee Inn
2.5 star property
8.6 out of 10, Excellent, (1000)
"Front desk very friendly and helpful. Room dated but clean. Complimentary parking in front of room, made it convenient to unload car or grab something from car as needed. Breakfast had a decent selection of items. Would come again. "
The price is SAR 431
SAR 478 total
includes taxes & fees
29 Sep - 30 Sep
Best Western Plus Santee Inn
Peach Tree Inn
2.5 star property
8.0 out of 10, Very Good, (35)
"Was great and the front desk staff awesome!"
The price is SAR 228
SAR 246 total
includes taxes & fees
24 Sep - 25 Sep
Peach Tree Inn
Red Roof Inn Santee
2.0 star property
6.4 out of 10, (570)
"Had the basics covered. Breakfast not too extensive, but room was clean, AC worked, quiet room, not so attractive property. But for the price, a good deal."
The price is SAR 248
SAR 275 total
includes taxes & fees
24 Sep - 25 Sep
Red Roof Inn Santee
Red Roof Inn St George, SC
2.5 star property
7.8 out of 10, Good, (527)
"Room was comfortable for the price. TV was snowy. Beds were comfortable."
The price is SAR 225
SAR 250 total
includes taxes & fees
24 Sep - 25 Sep
Red Roof Inn St George, SC
Knights Inn Saint George
1.5 star property
6.0 out of 10, (143)
"Great"
The price is SAR 189
SAR 210 total
includes taxes & fees
24 Sep - 25 Sep
Knights Inn Saint George
Super 8 by Wyndham Santee
2.0 star property
6.6 out of 10, (397)
"Very comfortable and convenient place to stay "
The price is SAR 263
SAR 292 total
includes taxes & fees
24 Sep - 25 Sep
Super 8 by Wyndham Santee
Econo Lodge St George
2.0 star property
6.4 out of 10, (215)
"Clean and everything worked well"
The price is SAR 204
SAR 220 total
includes taxes & fees
6 Oct - 7 Oct
Econo Lodge St George
Econo Lodge
2.0 star property
6.4 out of 10, (304)
"Check in was easy."
The price is SAR 241
SAR 267 total
includes taxes & fees
6 Oct - 7 Oct
Econo Lodge
Wyndham Vacation Resorts Lake Marion
4.0 star property
9.4 out of 10, Exceptional, (15)
"I enjoy my stay, customer service was exceptional. Will book again. "
Wyndham Vacation Resorts Lake Marion
Rodeway Inn Santee I-95
2.0 star property
6.2 out of 10, (503)
"The people were weird outside and the ice bucket didn’t come with a plastic bag in it. Everything else was good. Clean room, friendly man at the desk. "
Rodeway Inn Santee I-95
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
10.0 out of 10, Exceptional, (15)
"WILL STAY AGAIN."
The price is SAR 319
SAR 646 total
includes taxes & fees
5 Oct - 6 Oct
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
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Frequently asked questions

Where is the best place for a stay in Santee?

Fairfield Inn & Suites by Marriott Santee is a favorite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on traveler reviews include Hampton Inn Santee-I-95 and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.

What are some of the best vacation rentals in Santee?

Two Palms Lakehouse in Santee Just minutes from I95: Visitors give good reviews to this Santee vacation home rental, which is located on a lake and offers a barbecue grill, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

Where can I learn more about changing or cancelling my trip to Santee?

For more information about updating your trip to Santee or cancelling it, click here.

What's the best budget-friendly hotel in Santee?

Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.

What's the best hotel for a family vacation in Santee?

Comfort Inn & Suites Santee is a hotel with free parking and free buffet breakfast, and it's a top choice on Expedia for families. Fairfield Inn & Suites by Marriott Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.

What is the top LGBTQ-friendly accommodation in Santee?

Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee, an IHG Hotel are other good options for your stay.

What's the best pet-friendly accommodation in Santee?

Baymont by Wyndham Santee is a top hotel for people traveling with their pets, and offers concierge services and free WiFi for its human guests. Other good choices for you and your pet's trip include Quality Inn & Suites and Tru By Hilton Santee. See more pet-friendly hotel accommodations in Santee.

Where is the best place to stay near Santee State Park?

Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.

What about the best place to stay close to Santee Outlets?

One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.

What's the best golf hotel in Santee?

Holiday Inn Santee, an IHG Hotel is a top hotel that has an adjacent golf course and features free WiFi. Another good choice is Super 8 by Wyndham Santee if you'd like to be close to a golf course while in town. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.

What are some accommodations with pools in Santee?

Quality Inn & Suites is a top hotel with a seasonal outdoor pool, 7 restaurants, and free full breakfast. A couple of other options that offer an onsite pool include Comfort Inn & Suites Santee and Fairfield Inn & Suites by Marriott Santee. View all hotels with pools in Santee.

What's the best place to stay near Columbia Metropolitan Airport (CAE)?

Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.

What is staying in Santee like?

Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 86 hotels and other accommodations to choose from. Find out more about Santee.

What is there to see in Santee?

The picturesque setting of Santee State Park and Lake Marion exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Santee Cooper Country Club and Santee Outlets. Check out what more to see and do in Expedia's Santee guide.

What's the seasonal weather like in Santee?

The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.