Find Resorts & Hotels with Spas in Santee, SC

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Check availability on Santee Resorts & Hotels with Spas

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Property amenity

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1000)
"Great service, clean, and comfortable "
The price is SAR 536
SAR 595 total
includes taxes & fees
9 Apr - 10 Apr
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1001)
"What a fantastic place to stay and right off 95. Very clean, updated, and great staff. Breakfast looked good, although we weren’t hungry so we didn’t partake. This will be our go-to stop on our way to Florida. "
The price is SAR 525
SAR 583 total
includes taxes & fees
7 Apr - 8 Apr
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1291)
"Excellent stay."
The price is SAR 296
SAR 329 total
includes taxes & fees
27 Mar - 28 Mar
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (517)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (865)
"Really liked the free coffee, water station in the lobby and the friendly, helpful staff! The lighting in the bathroom was too dim. "
The price is SAR 465
SAR 516 total
includes taxes & fees
20 Apr - 21 Apr
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (602)
"Outside of the property does not do it justice it looks old but inside is a surprise, I was surprised everything was s new. Would I return ? Yes "
The price is SAR 229
SAR 254 total
includes taxes & fees
6 Apr - 7 Apr
Travelodge by Wyndham Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (381)
"Friendly and helpful staff, well maintained property."
The price is SAR 413
SAR 458 total
includes taxes & fees
6 Apr - 7 Apr
Tru By Hilton Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (598)
"Typical Red Roof Inn. We liked the parking at front door style of this motel and that was close to restaurants. The breakfast selection was not great, even for a continental. "
The price is SAR 263
SAR 291 total
includes taxes & fees
27 Mar - 28 Mar
Red Roof Inn Santee
Super 8 by Wyndham Santee
Lobby

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (418)
"Clean and tidy place bed a little lumpy but overall everything was good would I stay here again? Yes"
The price is SAR 281
SAR 312 total
includes taxes & fees
27 Mar - 28 Mar
Super 8 by Wyndham Santee
Lake Marion 3Bed/3Bath Deluxe!
Hair dryer, towels, soap, shampoo

Lake Marion 3Bed/3Bath Deluxe!

2.5 star property
Lake Marion 3Bed/3Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee National Golf Club. If you have a bit of extra time while you’re in the area, you might want to check out Santee State Park and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.