Find Resorts & Hotels with Spas in Santee, SC

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Santee Resorts & Hotels with Spas

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Property amenity

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1007)
"We only stayed once night as a stop over on our trip from FL to NY, and we had no complaints! We would stay again if passing through! "
The price is SAR 521
SAR 579 total
includes taxes & fees
24 Mar - 25 Mar
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1010)
"Smooth check in plus I had to make arrangements for a second night due to bad weather. I was taken care of with no problem."
The price is SAR 512
SAR 568 total
includes taxes & fees
25 Mar - 26 Mar
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1294)
"The overall stay at the Wyndham was good. The room was comfortable and clean. The only problem I had was the water pressure in the sink. The water comes out real slow and it didn't get hot enough. Everything else was good. The clerk at the desk for check in was awesome. Real friendly and explained everything nicely. "
The price is SAR 281
SAR 312 total
includes taxes & fees
20 Mar - 21 Mar
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (515)
"The property needs some work but it was quiet and close to a few restaurants we could walk to."
The price is SAR 227
SAR 252 total
includes taxes & fees
23 Mar - 24 Mar
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (859)
"It’s every spacious "
The price is SAR 411
SAR 456 total
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (597)
"For the most part, everything was good.Except for the half used shampoo bottle in the shower left from whoever was there before. "
The price is SAR 225
SAR 250 total
includes taxes & fees
23 Mar - 24 Mar
Travelodge by Wyndham Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (373)
"First time staying at a Tru - very cool and contemporary place. Room seemed cleaner than other places but maybe because the floors weren’t carpeted which may have added a feel of sterility. They have a 34 hour coffee area in the lobby but I didn’t see a coffee maker in the room which I wish they had as well."
The price is SAR 405
SAR 450 total
includes taxes & fees
23 Mar - 24 Mar
Tru By Hilton Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (596)
"The only thing I didn't like was the refrigerator wasn't working other than that everything was okay."
The price is SAR 263
SAR 291 total
includes taxes & fees
18 Mar - 19 Mar
Red Roof Inn Santee
Super 8 by Wyndham Santee
Lobby

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (418)
"Clean and tidy place bed a little lumpy but overall everything was good would I stay here again? Yes"
The price is SAR 281
SAR 312 total
includes taxes & fees
18 Mar - 19 Mar
Super 8 by Wyndham Santee
Lake Marion 3Bed/3Bath Deluxe!
Hair dryer, towels, soap, shampoo

Lake Marion 3Bed/3Bath Deluxe!

2.5 star property
Lake Marion 3Bed/3Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santee

Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee National Golf Club. If you have a bit of extra time while you’re in the area, you might want to check out Santee State Park and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.