Find Resorts & Hotels with Spas in Santee, SC

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Santee Resorts & Hotels with Spas

Compare Santee Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites by Marriott Santee
Lobby

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1001)
"The check in was very easy. There are plenty Parking "
The price is SAR 537
SAR 596 total
includes taxes & fees
17 Apr - 18 Apr
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1001)
"Only complaint is the entry tile floor and bathroom tile floors were dirty."
The price is SAR 548
SAR 609 total
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn Santee-I-95
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1299)
"Front desk was very helpful "
The price is SAR 300
SAR 333 total
includes taxes & fees
13 Apr - 14 Apr
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Room, 2 Double Beds, Non Smoking | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (519)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
The price is SAR 303
SAR 337 total
includes taxes & fees
11 May - 12 May
Ramada by Wyndham Santee I-95
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (870)
"Our room was wonderful. The staff was so very nice, both at check in and in the restaurant "
The price is SAR 435
SAR 483 total
includes taxes & fees
13 May - 14 May
Holiday Inn Santee by IHG
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (604)
"For the most part, everything was good.Except for the half used shampoo bottle in the shower left from whoever was there before. "
The price is SAR 229
SAR 254 total
includes taxes & fees
20 Apr - 21 Apr
Travelodge by Wyndham Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | Free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.0 out of 10, Wonderful, (395)
"This property was clean & convenient; the staff was amazing! Breakfast was great and we had a wonderful experience overall. "
The price is SAR 413
SAR 458 total
includes taxes & fees
11 May - 12 May
Tru By Hilton Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (603)
"Comfortable , clean and friendly. Very convenient location."
The price is SAR 263
SAR 292 total
includes taxes & fees
13 Apr - 14 Apr
Red Roof Inn Santee
Super 8 by Wyndham Santee
Exterior

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (419)
"Clean and tidy place bed a little lumpy but overall everything was good would I stay here again? Yes"
The price is SAR 282
SAR 313 total
includes taxes & fees
13 Apr - 14 Apr
Super 8 by Wyndham Santee
Lake Marion 2Bed/2Bath Deluxe!
Interior

Lake Marion 2Bed/2Bath Deluxe!

2.5 star property
Lake Marion 2Bed/2Bath Deluxe!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santee

Frequently asked questions

Looking for a spa hotel in Santee?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers recommend the gourmet restaurants in Santee. Be sure to enjoy activities like fishing and golfing during your stay. Hotels with spas are a great way to break out of your routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Santee?
Among Expedia’s 36 accommodation options in Santee, there is 1 spa hotel.
What's there to see and do in Santee?
Enjoy all that Santee has to offer when you visit Santee Cooper Country Club, Santee Outlets, and Santee National Golf Club. If you have a bit of extra time while you’re in the area, you might want to check out Santee State Park and Santee Town Hall.
What is a Santee spa hotel?
Spa hotels in Santee provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.