Find Family Hotels in Santee, SC

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Santee Family Hotels

Compare Santee Family Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (960)
"Parking spaces were to small, had to crawl through car to get out 😞."
The price is SAR 411
SAR 457 total
includes taxes & fees
13 Apr - 14 Apr
Comfort Inn & Suites Santee
Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1008)
"What a fantastic place to stay and right off 95. Very clean, updated, and great staff. Breakfast looked good, although we weren’t hungry so we didn’t partake. This will be our go-to stop on our way to Florida. "
The price is SAR 528
SAR 586 total
includes taxes & fees
7 Apr - 8 Apr
Hampton Inn Santee-I-95
Best Western Plus Santee Inn
Exterior

Best Western Plus Santee Inn

2.5 star property
8.8 out of 10, Excellent, (1004)
"Customer services. Barbara whowas in charge of the buffet breakfast was working very hard, cleaning the area and made sure all breakfast was available for everyone.She is very nice and "
The price is SAR 415
SAR 460 total
includes taxes & fees
9 Apr - 10 Apr
Best Western Plus Santee Inn
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very Good, (865)
"Really liked the free coffee, water station in the lobby and the friendly, helpful staff! The lighting in the bathroom was too dim. "
The price is SAR 439
SAR 487 total
includes taxes & fees
27 Apr - 28 Apr
Holiday Inn Santee by IHG
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (307)
"Check in was easy."
Econo Lodge
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (602)
"For the most part, everything was good.Except for the half used shampoo bottle in the shower left from whoever was there before. "
The price is SAR 229
SAR 254 total
includes taxes & fees
6 Apr - 7 Apr
Travelodge by Wyndham Santee
Super 8 by Wyndham Santee
Lobby

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (418)
"Clean and tidy place bed a little lumpy but overall everything was good would I stay here again? Yes"
The price is SAR 281
SAR 312 total
includes taxes & fees
30 Mar - 31 Mar
Super 8 by Wyndham Santee
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1330)
"A clean, comfortable hotel. Only downside was the minimalist breakfast bar with no scrambled eggs and bacon/sausage. Our third stay here and we will probably stay here again. Keith, Toronto March 2025"
The price is SAR 300
SAR 333 total
includes taxes & fees
30 Mar - 31 Mar
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (517)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
Ramada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santee

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you’ve been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it’s a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
How many hotels that welcome families will I find in Santee?
Expedia has 10 family-friendly hotels and other accommodations in Santee.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you might want to check out some kid-friendly attractions such as Santee Outlets and Santee Indian Mound and Fort Watson Site. Make sure you have lots of time for activities like Orangeburg County Library Mentor Branch and Santee National Wildlife Refuge.