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Compare 61 Vacation Homes in Santee with updated reviews, rates, and availability.

Wyndham Vacation Resorts Lake Marion
Exterior

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.4 out of 10, Exceptional, (16)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Beautiful panoramic view

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

10.0 out of 10, Exceptional, (133)
"100% perfect plenty of items to use and fishing was great got a 25 pound blue cat off the dock as well as 2 giant stripers as well as crappy and perch. just cast to the left in Gibbins hole "look on the map on the wall" directly in front of dock is a brush pile to the right is ok. nice and quiet host had lots of games and food available room are perfect . well i cant sat enough good things and i can not think of any bad things to talk about 'THERE IS NONE LOL" thank you for the best stay ever we...
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Tom Charles Goat Island Fishing Retreat
Living area

Tom Charles Goat Island Fishing Retreat

9.8 out of 10, Exceptional, (45)
"Errol and I have stayed at this location on several occasions and have found the location perfect for fishing Santee. Good parking for boat and trailer. Screen porch is a great place to relax and take in the beautiful lake. I plan on at least 4 future trips in 2025. Thank you"
Tom Charles Goat Island Fishing Retreat
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Sandy beach with a beautiful view

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

9.8 out of 10, Exceptional, (221)
"House is in a great location on Lake Marion. House is very dated but overall a very nice stay. Well stocked for dishes so easy to cook. Would definitely stay there again. "
The price is SAR 1,502
SAR 2,523 total
includes taxes & fees
30 Nov - 1 Dec
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Beautiful 5br, 3 full bath home on Lake Marion with private pier/dock.

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

9.6 out of 10, Exceptional, (74)
"Great trip for our 40 year friendship."
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Property grounds

The Bunkhouse at St Julien - Vintage Waterfront Lake House

9.8 out of 10, Exceptional, (15)
"This property was perfect for a nice relaxing weekend away. They had pretty much everything you could possibly need and more."
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Jewel on the Lake - Relaxing Lakefront Home
Serenity now....

Jewel on the Lake - Relaxing Lakefront Home

9.8 out of 10, Exceptional, (16)
"Cute house good location "
Jewel on the Lake - Relaxing Lakefront Home
Cozy & Peaceful 3 bed 2 bath On the Water
Miscellaneous

Cozy & Peaceful 3 bed 2 bath On the Water

10.0 out of 10, Exceptional, (27)
"Great trip!!!!"
Cozy & Peaceful 3 bed 2 bath On the Water
Idyllic Waterfront Escape w/ Private Boat Dock!
Summerton Vacation Rental | 3BR | 2BA | 1,200 Sq Ft | Step-Free Access

Idyllic Waterfront Escape w/ Private Boat Dock!

10.0 out of 10, Exceptional, (23)
"A beautiful lake house with million dollar sunset views. We absolutely loved the house. Communication with the host was exceptional. Wish we could have stayed longer. "
Idyllic Waterfront Escape w/ Private Boat Dock!
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Multiple seating options make this deck a space where your whole group can hang out and enjoy the views of Lake Marion.

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (28)
"This home is situated in a very peaceful neighborhood. It was very clean and had little things that made it great like the snack tray and the K-cups. The fenced yard was great for our fur baby. "
The price is SAR 541
SAR 1,414 total
includes taxes & fees
3 Dec - 4 Dec
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Fabulous Location on southern shores of Lake Marion
Waterside of Home Large screened porch plus private Master bdrm screened porch

Fabulous Location on southern shores of Lake Marion

9.4 out of 10, Exceptional, (10)
"This property was over the top and way above my expectations. Highly recommend."
Fabulous Location on southern shores of Lake Marion
Beautiful Cottage between Lake Moultrie and Lake Marion
Welcome to the A-Frame

Beautiful Cottage between Lake Moultrie and Lake Marion

9.8 out of 10, Exceptional, (128)
"We loved our stay at the A frame! Very cool building and it had everything we needed!"
Beautiful Cottage between Lake Moultrie and Lake Marion
LAKE MARION LAKE FRONT VACATION RENTAL
Front Road Side

LAKE MARION LAKE FRONT VACATION RENTAL

9.6 out of 10, Exceptional, (79)
"We needed a small weekend getaway and this was perfect! The lake was low but it was still fun pontooning around the lake, the beds and couches are so comfortable. Thank you Mrs Wendy for hosting us again, we can’t wait to come back in the summer! 😊"
LAKE MARION LAKE FRONT VACATION RENTAL
Archie's Lake Daze Cottage
Relax on a rocking chair and enjoy the view

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (63)
"The property was great. Everything was super clean. There was lots of fun things to do and the setting was perfect."
Archie's Lake Daze Cottage
Dukes Street Retreat 5min from I-95!
Front of the House

Dukes Street Retreat 5min from I-95!

8.0 out of 10, Very Good, (10)
"We felt so special staying in such a beautiful home! It was well stocked and laid out perfectly for a wonderful family time. Nice neighborhood. We felt perfectly safe."
Dukes Street Retreat 5min from I-95!
Quaint Orangeburg Townhome Near Hospitals & Campus
Orangeburg Vacation Rental | 3BR | 3BA | Stairs Required | 1,044 Sq Ft

Quaint Orangeburg Townhome Near Hospitals & Campus

7.6 out of 10, Good, (5)
"Good"
Quaint Orangeburg Townhome Near Hospitals & Campus
Hotel Double Room Pet-friendly - Hotel Double Room, Pet-friendly
Bedroom

Hotel Double Room Pet-friendly - Hotel Double Room, Pet-friendly

10.0 out of 10, Exceptional, (1)
"We really enjoyed our stay! Easy access to the lake and nice room."
The price is SAR 349
SAR 528 total
includes taxes & fees
26 Nov - 27 Nov
Hotel Double Room Pet-friendly - Hotel Double Room, Pet-friendly
Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!
Such a fun house! (Back View)

Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!

2.0 star property
9.0 out of 10, Wonderful, (2)
"The lake home has tons of natural light and we loved watching the many beautiful geese. The house is situated in a safe and lovely neighborhood. It’s a great area to take a quiet morning or afternoon walk. The open living room area is a great place for families. Our teens loved the board games and puzzle provided for guests. Maggie was a great host. She was responsive and very good to deal with. The back deck was great for grilling….. with a choice of a propane or charcoal grill. We enjoyed a...
Waterfront, Dock, Boat Landing...The Calm On The Cove Sleeps 8!
Lake Marion Home: Kayaks, Dock, Waterfront Fun!
Summerton Vacation Rental | 3BR | 2BA | 1,800 Sq Ft | Stairs to Enter

Lake Marion Home: Kayaks, Dock, Waterfront Fun!

7.0 out of 10, Good, (2)
"This property was a very nice getaway for my friend and I. We enjoyed the quite neighborhood and sitting on the back porch enjoying the early fall weather. Hope to stay again in the future. "
Lake Marion Home: Kayaks, Dock, Waterfront Fun!
The Alamo on Lake Marion
Lakeside of house. Large yard. Peddle boat and kayaks for added fun!

The Alamo on Lake Marion

6.6 out of 10, (8)
"Plenty of room for big group. Lots of potential. Would stay again"
The Alamo on Lake Marion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Santee

Wyndham Vacation Resorts Lake Marion
Exterior

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.4 out of 10, Exceptional, (16)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Pool

Executive 2 BR/2 BA Lakefront Corner Suite Condo

9.0 out of 10, Wonderful, (31)
"We live and work locally and had to move out of our house for a week while our hardwood floors were being redone after a major water leak. This place worked out great. Almost like a mini vacation! "
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Multiple seating options make this deck a space where your whole group can hang out and enjoy the views of Lake Marion.

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (28)
"This home is situated in a very peaceful neighborhood. It was very clean and had little things that made it great like the snack tray and the K-cups. The fenced yard was great for our fur baby. "
The price is SAR 541
SAR 1,414 total
includes taxes & fees
3 Dec - 4 Dec
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.