Find Luxury Hotels in Santee, SC

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Check availability on Santee Luxury Hotels

Compare Santee Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Red Roof Inn Santee
Room

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (594)
"The only thing I didn't like was the refrigerator wasn't working other than that everything was okay."
The price is SAR 251
SAR 279 total
includes taxes & fees
23 Feb - 24 Feb
Red Roof Inn Santee
Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (943)
"The Front Desk workers are friendly and effecient!"
The price is SAR 411
SAR 456 total
includes taxes & fees
2 Mar - 3 Mar
Comfort Inn & Suites Santee
Baymont by Wyndham Santee
Exterior

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1278)
"Clean comfortable, slept well."
The price is SAR 281
SAR 312 total
includes taxes & fees
23 Feb - 24 Feb
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Room

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (510)
"Great cheesesteak and friendly management. "
The price is SAR 303
SAR 336 total
includes taxes & fees
2 Mar - 3 Mar
Ramada by Wyndham Santee I-95
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (307)
"Check in was easy."
The price is SAR 304
SAR 338 total
includes taxes & fees
9 Mar - 10 Mar
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in Santee?
Let Expedia help you arrange your flight to Columbia Metropolitan Airport (CAE) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you’d like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Santee has to offer. During your visit, you might want to enjoy the restaurants and coffee shops which Santee is known for.
How many luxury hotels will I be able to find in Santee?
Lie in the lap of luxury during your getaway to Santee in one of Expedia’s 8 luxury hotels.
When can I expect good weather in Santee?
Planning for the weather is an important factor for making your trip to Santee a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do in Santee?
Enjoy all that Santee has to offer and visit Santee Cooper Country Club, Santee Outlets, and Santee State Park. If you have a little extra time during your trip, you might want to make a stop at Lake Marion and Santee National Golf Club.