Photo by Hideki Yamagata

Find Resorts & Hotels with Spas in San Francisco

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on San Francisco Resorts & Hotels with Spas

Compare San Francisco Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Sheraton Grand Panama
View from property

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (869)
"Great place to stay"
The price is SAR 472
SAR 519 total
includes taxes & fees
25 May - 26 May
Sheraton Grand Panama
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"Great hotel"
The price is SAR 953
SAR 1,049 total
includes taxes & fees
1 Jun - 2 Jun
JW Marriott Panama
Aloft Panama
Exterior

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (804)
"Great place to stay if your traveling with family."
The price is SAR 427
SAR 470 total
includes taxes & fees
25 May - 26 May
Aloft Panama
Plaza Paitilla Inn Hotel
View from property

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2028)
"Family enjoyed their stay"
The price is SAR 413
SAR 454 total
includes taxes & fees
12 May - 13 May
Plaza Paitilla Inn Hotel
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (461)
"This is a well maintained property, it is very clean and I found the amenities very convenient. The breakfast options were really good as well. The hotel staff were friendly and very helpful. "
The price is SAR 507
SAR 558 total
includes taxes & fees
16 May - 17 May
Residence Inn by Marriott Panama City
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (883)
"Property I’d very nice clean and in a very nice and safe area"
The price is SAR 476
SAR 524 total
includes taxes & fees
24 May - 25 May
Megapolis Hotel Panamá
Courtyard by Marriott Panama Multiplaza Mall
Lounge

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1000)
"It was quiet staff very helpful worth the stay"
The price is SAR 486
SAR 535 total
includes taxes & fees
23 May - 24 May
Courtyard by Marriott Panama Multiplaza Mall
Ramada Plaza By Wyndham Panama Punta Pacífica
Outdoor pool, pool umbrellas, sun loungers

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (999)
"Great place to stay"
The price is SAR 411
SAR 452 total
includes taxes & fees
22 May - 23 May
Ramada Plaza By Wyndham Panama Punta Pacífica
Decapolis Hotel Panama City
Exterior

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1184)
"Great location "
The price is SAR 324
SAR 356 total
includes taxes & fees
7 Jun - 8 Jun
Decapolis Hotel Panama City
Diaphanous Urban Apartment
City view

Diaphanous Urban Apartment

3.5 star property
9.2 out of 10, Wonderful, (5)
"I highly highly recommend this apartment. Best AC you will find In panama. Very clean, spacious, everything worked as it should. This is now my go to place while visiting Panama. The dining options are vast and close. Many top restaurants are near by. And parque Omar for your morning walks. Pet friendly. Don’t look elsewhere. "
Diaphanous Urban Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in San Francisco

Frequently asked questions

Looking for a spa hotel in San Francisco?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Be sure to enjoy the many popular restaurants during your stay. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in San Francisco?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a rooftop terrace. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in San Francisco include Decapolis Hotel Panama City and Las Americas Golden Tower Panama.
How many spa hotels will I find in San Francisco?
Among Expedia’s 194 accommodation options in San Francisco, there are 4 spa hotels.
What's there to see and do in San Francisco?
Enjoy San Francisco and visit Multiplaza Pacific Mall, Calle 50, and Avenida Balboa. If you have spare time during your trip, you might want to make a stop at Panama Canal Murals and Pacific Center.
What is a San Francisco spa hotel?
Spa hotels in San Francisco provide lodging and have an on-site spa which offers services like therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.