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Compare 141 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG
9.4 out of 10, Exceptional, (457)
The price is SAR 386
SAR 442 total
includes taxes & fees
4 May - 5 May

Urban Lofts
Urban Lofts
9.2 out of 10, Wonderful, (17)
The price is SAR 840
SAR 1,203 total
includes taxes & fees
28 Apr - 29 Apr

Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
8.4 out of 10, Very Good, (846)
The price is SAR 271
SAR 310 total
includes taxes & fees
4 May - 5 May

Days Inn by Wyndham Perryville
Days Inn by Wyndham Perryville
6.8 out of 10, (397)
The price is SAR 300
SAR 344 total
includes taxes & fees
4 May - 5 May

Quality Inn Perryville I-55
Quality Inn Perryville I-55
6.8 out of 10, (103)
The price is SAR 303
SAR 347 total
includes taxes & fees
4 May - 5 May

Baymont by Wyndham Chester IL
Baymont by Wyndham Chester IL
8.6 out of 10, Excellent, (296)
The price is SAR 360
SAR 399 total
includes taxes & fees
30 Apr - 1 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Perryville and related destinations
Perryville is calling! Discover its wineries, golf, university life, and more.
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Photo by Cindy Woodford
Open Photo by Cindy Woodford
Come to Camden and enjoy its football, entertainment, and wineries.
More cheap stays in Perryville
More cheap stays in Perryville

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
The price is SAR 313 per night from May 4 to May 5
SAR 313
SAR 338 total
includes taxes & fees
4 May - 5 May
8.8/10 Excellent! (541 reviews)
Hotels in Perryville with star-rating
Hotels in Perryville with star-rating

4 Star Hotels
1 properties
Stay near popular Perryville attractions
Stay near popular Perryville attractions
National Shrine of Our Lady of the Miraculous Medal
4.5/5(9 reviews)
Find out about the history of Perryville when you take a trip to National Shrine of Our Lady of the Miraculous Medal. Take in the festivals while you're in the area.
Recent reviews of Perryville hotels
Recent reviews of Perryville hotels

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
5/5 Excellent
"The hotel is beautiful "
A verified traveler stayed at Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Posted 1 day ago
Explore a world of travel with Expedia
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Stay near popular Perryville attractions
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Perryville Country Club
- Hotels near Missouri's National Veterans Memorial
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Sainte Genevieve Winery
- Hotels near Hunter Valley Winery
- Hotels near Crown Valley Winery
- Hotels near Pickle Springs Natural Area
- Hotels near Hawn State Park
- Hotels near Cave Vineyard
- Hotels near Trail of Tears State Park
- Hotels near Lake Murphysboro State Park
- Hotels near Popeye Museum
- Hotels near Pomona Winery
- Hotels near Fort Kaskaskia
More Hotel Options in Perryville
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- Hotels with Free Parking in Perryville
- Hotels with Hot Tubs in Perryville
- Hotels with WiFi in Perryville
- Hotels with a Pool in Perryville
- Hotels with an Indoor Pool in Perryville
- Pet-friendly Hotels in Perryville
- Resorts & Hotels with Spas in Perryville
- Winery Hotels in Perryville
Hotels near Perryville Airports
Perryville Hotels by Brand
Other Hotels near Perryville, Missouri
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Explore more hotels
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- Beautiful location in the secluded woods
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- Secluded Cabin with Heated Pool, hot tub, fireplace & so much more