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Perryville and related destinations
Perryville is calling! Discover its wineries, golf, university life, and more.
Get away to trendy Fergus Falls! Enjoy the waterfalls, culture, and coffee.
Quaint Higginsville awaits: its university life, gardens, beer, and more!
Get away to quaint Kewanee! Enjoy the cafes, countryside, and golf.

Photo by Cindy Woodford
Open Photo by Cindy Woodford
Come to Camden and enjoy its football, entertainment, and fishing.
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Perryville Hotels by Star Rating
Stay near popular Perryville attractions
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Perryville Country Club
- Hotels near Missouri's National Veterans Memorial
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Sainte Genevieve Winery
- Hotels near Trail of Tears State Park
- Hotels near Pickle Springs Natural Area
- Hotels near Crown Valley Winery
- Hotels near Hawn State Park
- Hotels near Hunter Valley Winery
- Hotels near Lake Murphysboro State Park
- Hotels near Fort Kaskaskia
- Hotels near Pomona Winery
- Hotels near Cave Vineyard
- Hotels near Twin Oaks Vineyard & Winery
More Hotel Options in Perryville
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- Hotel Wedding Venues in Perryville
- Hotels with Bars in Perryville
- Hotels with Free Parking in Perryville
- Hotels with Hot Tubs in Perryville
- Hotels with WiFi in Perryville
- Hotels with a Pool in Perryville
- Hotels with an Indoor Pool in Perryville
- Pet-friendly Hotels in Perryville
- Resorts & Hotels with Spas in Perryville
- Winery Hotels in Perryville
Explore more hotels
- Town House Inn
- Beautiful location in the secluded woods
- Secluded Cabin with Heated Pool, hot tub, fireplace & so much more
- Comfort Suites Jackson-Cape Girardeau
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Baymont by Wyndham Chester IL
- Secluded Private Cabin with Pool, hot tub, fireplace & so much more
- Briarwood Inn of Sparta
- Rated#1 Big Sky Cabin! 🍷 On the Wine Trail Hot Tub 🔥 FirePit Pool 🎱 Table
- Madison Inn Lodge
- Missouri Castle w/ Private Lake, Pool & 100 Acres!
- Romantic renovated country cabin with views.
- The Conner House B&B
- Tru By Hilton Cape Girardeau
- Beautiful Modern Loft In Wine Country!
- THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek
- "Little Brick House on Main (1865)”
- Charming 2-bedroom house in delightful Jackson with AC, WiFi
- St Francis River: The Blue Yurt and Hot Tub