Find hotels in Murphysboro, IL from SAR 212
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Compare 277 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
9.4 out of 10, Exceptional, (406)
The price is SAR 431
SAR 479 total
includes taxes & fees
27 Mar - 28 Mar

Gray Plaza Motel
Gray Plaza Motel
6.8 out of 10, (46)
The price is SAR 266
SAR 295 total
includes taxes & fees
15 Mar - 16 Mar

Americas Best Value Inn Marion, IL
Americas Best Value Inn Marion, IL
5.8 out of 10, (466)
The price is SAR 225
SAR 270 total
includes taxes & fees
16 Mar - 17 Mar

Econo Lodge
Econo Lodge
5.2 out of 10, (297)
The price is SAR 212
SAR 254 total
includes taxes & fees
16 Mar - 17 Mar

Americas Best Value Inn West Frankfort
Americas Best Value Inn West Frankfort
7.6 out of 10, Good, (422)
The price is SAR 300
SAR 333 total
includes taxes & fees
16 Mar - 17 Mar

Best Western Marion Hotel
Best Western Marion Hotel
8.2 out of 10, Very Good, (1003)
The price is SAR 286
SAR 344 total
includes taxes & fees
1 Apr - 2 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Murphysboro
Escape to Murphysboro! Enjoy its fishing, food, and museums.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
More cheap stays in Murphysboro
More cheap stays in Murphysboro

Baymont by Wyndham Marion
2608 W Main St, Marion, IL
The price is SAR 311 per night from Apr 6 to Apr 7
SAR 311
SAR 373 total
includes taxes & fees
6 Apr - 7 Apr
8.2/10 Very Good! (1,001 reviews)
Hotels in Murphysboro with star-rating
Hotels in Murphysboro with star-rating

4 Star Hotels
2 properties
Stay near popular Murphysboro attractions
Stay near popular Murphysboro attractions

Lake Murphysboro State Park
4/5(15 reviews)
You can take time to visit Lake Murphysboro State Park during your travels to Murphysboro. You can enjoy the coffeehouses while in the area.
Recent reviews of Murphysboro hotels
Recent reviews of Murphysboro hotels

Comfort Inn & Suites Carbondale University Area
5/5 Excellent
"The stay was nice. Would stay again"
A verified traveler stayed at Comfort Inn & Suites Carbondale University Area
Posted 16 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Stay near popular Murphysboro attractions
- Hotels near Lake Murphysboro State Park
- Hotels near Hickory Ridge Public Golf Center
- Hotels near General John A. Logan Museum
- Hotels near Shawnee National Forest
- Hotels near Southern Illinois University
- Hotels near Mississippi River
- Hotels near Lake of Egypt
- Hotels near Giant City State Park
- Hotels near DuQuoin State Fairgrounds
- Hotels near Blue Sky Vineyards
- Hotels near Marion Cultural and Civic Center
- Hotels near I-57 Drag Strip
- Hotels near John A. Logan College
- Hotels near Trail of Tears State Park
More Hotel Options in Murphysboro
More Accommodation Types in Murphysboro
- Vacation Homes in Murphysboro
- Cabin Rentals in Murphysboro
- Apartments in Murphysboro
- Motels in Murphysboro
- Cottages in Murphysboro
- RV Parks in Murphysboro
- B&B in Murphysboro
- Lodges in Murphysboro
- Farmstay in Murphysboro
- Condo Rentals in Murphysboro
- Guest Houses in Murphysboro
- Resorts in Murphysboro
- Villas in Murphysboro
Hotels near Murphysboro Airports
Murphysboro Hotels by Brand
Other Hotels near Murphysboro, Illinois
- Cape Girardeau Hotels
- Marion Hotels
- Carbondale Hotels
- Ozarks Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Perryville Hotels
- Anna Hotels
- Makanda Hotels
- Central United States Hotels
- Carterville Hotels
- Du Quoin Hotels
- Goreville Hotels
- Cobden Hotels
- Creal Springs Hotels
- Alto Pass Hotels
- Sparta Hotels
- Benton Hotels
- Pinckneyville Hotels
- West Frankfort Hotels
Explore more hotels
- Super 8 by Wyndham Carbondale
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Best Western Saluki Inn
- Americas Best Value Inn Marion, IL
- Rest, Relax and Renew. Our log cabin experience awaits your arrival.
- New cabin in the woods with private hot tub
- Comfort Inn & Suites Carbondale University Area
- Holiday Inn Carbondale-Conference Center by IHG
- Beautiful location in the secluded woods
- Quality Inn Carbondale University area
- Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
- Pinckeyville Inn and Suites