Find Luxury Hotels in Mission District, CA

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Check availability on Mission District Luxury Hotels

Compare Mission District Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

El Capitan Hotel
Front of property

El Capitan Hotel

2.0 star property
4.6 out of 10, (826)
"Mission district is amazing for food and nightlife. Stayed here because of that. Made a mistake roaches and bugs in the room. Crackheads in parking lot break on to your car (no security) "
El Capitan Hotel
Inn San Francisco
Outdoor spa tub

Inn San Francisco

2.5 star property
9.6 out of 10, Exceptional, (520)
"Breakfast"
The price is SAR 844
SAR 982 total
includes taxes & fees
28 Apr - 29 Apr
Inn San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Mission District?
Use Expedia to arrange your flight to San Francisco Intl. Airport (SFO) airport or Oakland Intl. Airport (OAK) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Mission District offers. During your visit, you might want to enjoy the bars which Mission District is known for.
How many luxury hotels can I expect to find in Mission District?
Lie in the lap of luxury during your getaway to Mission District in one of Expedia’s 5 luxury hotels.
What's the best time to vacation in Mission District?
The hottest months are usually September and August with an average temperature of 64°F,
  • Coldest months: January, February, December, and March
  • Driest months: August, July, September, and June
  • Rainiest months: December, January, February, and March
What's there to see and do in Mission District?
Take in the sights and attractions that Mission District offers with a visit to San Francisco Public Library, Mission San Francisco de Asís, and SOMA Pilipinas. If you have spare time during your trip, you might want to make a stop at Hua Zang Si and Paxton Gate.
How can I get around Mission District?
It’s easier to get around town comfortably when you know your options. Nearby metro stations include 16th Street Mission Station, 24th Street Mission Station, and Right Of Way/20th St Stop.