Find Resorts & Hotels with Spas in Mission District, CA

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Mission District Resorts & Hotels with Spas

Compare Mission District Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Inn San Francisco

2.5 star property
9.6 out of 10, Exceptional, (516)
"Beautiful historic property. Easy walking distance to good restaurants and shops. Great breakfast "
The price is SAR 835
SAR 972 total
includes taxes & fees
11 Mar - 12 Mar
Inn San Francisco

Noe's Nest Bed and Breakfast

3.5 star property
9.4 out of 10, Exceptional, (104)
"We only could be there one night, but you’d need days to take in all the art and artifacts Sheila has on display. We got a fascinating tour and were then shown up to our suite, very comfortable and cozy. This Victorian house is beautifully maintained and the yard is inviting. Sadly, we weren’t there long enough to enjoy it or even have breakfast in the warm and inviting kitchen. Next time."
The price is SAR 844
SAR 982 total
includes taxes & fees
6 Mar - 7 Mar
Noe's Nest Bed and Breakfast

Union Hotel

2.0 star property
7.0 out of 10, Good, (262)
"I wasn't expecting a lot, but was pleasantly surprised by the friendliness of the staff and the cleanliness of the room and bathrooms. I like the Mission district and it's colorful atmosphere, and never felt unsafe. The crowds and noise did not bother me, I found it entertaining. Price was reasonable, and with so many places to eat and BART right there, it was great for me. Best thing was late night buses to the airport were available several short blocks away and were inexpensive and very...
The price is SAR 203
SAR 236 total
includes taxes & fees
11 Mar - 12 Mar
Union Hotel

Parker Guest House San Francisco

3.5 star property
9.4 out of 10, Exceptional, (403)
"They think of everything.... snacks, wine social, games to play by fireside,beautiful floral arrangements everywhere "
The price is SAR 746
SAR 870 total
includes taxes & fees
12 Mar - 13 Mar
Parker Guest House San Francisco

Charming 1 bed 1bath - 1 block to Dolores Park

Charming 1 bed 1bath - 1 block to Dolores Park

Quiet One Bedroom Suite in The Mission near Castro

10.0 out of 10, Exceptional, (2)
"This was so convenient. A block and a half from our daughter, 3 blocks from BART. The place was very clean and well appointed. I knew it was a basement unit, but at first was surprised when entering through the garage and almost no natural light. We were using it primarily as a place to sleep so that wasn't an issue. Didn't use the advertised outdoor space--it wasn't great. However, for a clean, quiet, convenient place to stay, I recommend this. We will return."
The price is SAR 656
SAR 1,258 total
includes taxes & fees
5 Mar - 6 Mar
Quiet One Bedroom Suite in The Mission near Castro

Colorful Mission District! Amazing Location! Comfortable Private Garden In-Law

10.0 out of 10, Exceptional, (47)
"I stayed here for a month for a medical procedure that required I stay in the area for a month. Great location for necessities and dining options, the garden area is welcoming I regret not spending more time in it"
Colorful Mission District! Amazing Location! Comfortable Private Garden In-Law

Jackson Square / Barbary Coast Living

9.8 out of 10, Exceptional, (30)
"I booked the place for a few of my coworkers visiting our headquarters in San Francisco. Everybody loved the place and gave me great feedback: the rooms were very nice, the location - - convenient, and the communication with the host was very easy. We'd recommend the place to anybody."
Jackson Square / Barbary Coast Living

Cute 1 bed 1 bath Apt in Sunny and Hip Mission District

9.4 out of 10, Exceptional, (16)
"I stayed at Brian’s place in the Mission for nine weeks and it was perfect. There are lots of great restaurants and shops on Valencia. Easy and safe to talk to and from the train that’s just a few blocks away. The property itself is fairly spacious, well equipped, and very clean. Brian was very prompt in his responses to any inquiry I had. At one point there was an issue with the dryer and he had someone out to fix it the very next day. I would definitely stay here again in the future!"
Cute 1 bed 1 bath Apt in Sunny and Hip Mission District

Amazing Roof Deck in the Mission! Walk to Tartine Manufacture

9.6 out of 10, Exceptional, (15)
"Lots of room to entertain. The apartment furnishing need a little help. Kitchen was well stocked with cookware etc. We used the upper deck a lot but cushions were lacking. Plants and planters were in disrepair. However we would love to stay here again. The sunny Mission was true to its name. We walked everywhere with no problem. Didn’t walk past 17th, 16th st etc.on purpose. Having lived in SF in the 70’s it’s not the same city, homeless everywhere, garbage etc all over the streets and...
Amazing Roof Deck in the Mission! Walk to Tartine Manufacture
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Mission District

Frequently asked questions

Looking to vacation at a spa hotel in Mission District?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the art galleries and bars in Mission District—your day trip starts here. Be sure to pay a visit to the museums during your stay. Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your vacation.
How many spa hotels are there in Mission District?
Among Expedia’s 95 accommodation options in Mission District, there are 2 spa hotels.
What's there to see and do in Mission District?
Experience Mission District with a stop at San Francisco Public Library, Mission Dolores Park, and Victoria Theatre. If you have a little extra time during your trip, you might want to make a stop at SF Armory and Mission San Francisco de Asís.
What is a Mission District spa hotel?
Spa hotels in Mission District provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.