Find Resorts & Hotels with Spas in Main Street Hyannis, MA

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Main Street Hyannis Resorts & Hotels with Spas

Compare Main Street Hyannis Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Americas Best Value Inn & Suites Hyannis Cape Cod
Pool

Americas Best Value Inn & Suites Hyannis Cape Cod

2.0 star property
7.6 out of 10, Good, (1001)
"Good"
Americas Best Value Inn & Suites Hyannis Cape Cod
Hyannis Inn
Indoor pool

Hyannis Inn

2.0 star property
8.6 out of 10, Excellent, (972)
"I continue to stay here when I have business in the area. "
Hyannis Inn
Hyannis Plaza Hotel
Outdoor pool

Hyannis Plaza Hotel

2.5 star property
7.0 out of 10, Good, (693)
"Nice "
The price is SAR 302
SAR 377 total
includes taxes & fees
24 Feb - 25 Feb
Hyannis Plaza Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Main Street Hyannis

Frequently asked questions

Looking to vacation at a spa hotel in Main Street Hyannis?
Forget the stress of everyday life and book yourself a lush spa hotel. Travelers highly recommend the restaurants in Main Street Hyannis. Enjoy the shopping and beaches during your vacation. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your holiday.
How many spa hotels will I find in Main Street Hyannis?
Among Expedia’s 15 accommodation options in Main Street Hyannis, there is 1 spa hotel.
What's there to see and do in Main Street Hyannis?
When you’re in Main Street Hyannis, enjoy exploring the sights and attractions here including John F. Kennedy Hyannis Museum, Cape Cod Baseball Hall of Fame, and Wackenhammer’s Clockwork Arcade. If you have spare time during your trip, you might want to make a stop at Hyannis Harbor and John F. Kennedy Memorial.
What is a Main Street Hyannis spa hotel?
Spa hotels in Main Street Hyannis provide lodging and have an on-site spa offering services such as facials and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.