Find Family Hotels in Main Street Hyannis, MA

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Pick from 4 Main Street Hyannis Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Americas Best Value Inn & Suites Hyannis Cape Cod
2.0 star property
7.6 out of 10, Good, (1002)
"Cute beachy stay in the heart of Hyannis! Super walkable and near the harbor!"
Americas Best Value Inn & Suites Hyannis Cape Cod
Comfort Inn Hyannis - Cape Cod
2.5 star property
7.6 out of 10, Good, (1003)
"Have stayed here many times. It is always quiet and comfortable."
The price is SAR 343
SAR 392 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn Hyannis - Cape Cod
Cape Cod Inn
2.0 star property
8.8 out of 10, Excellent, (422)
"The Cape Cod Inn is a decent motel. The rooms are clean and spacious and quiet. We found it very convenient to park outside our door. It’s a very short walk to restaurants and shops and a ten minute walk to the ferry to either Nantucket or Martha’s Vineyard. Good value for the money, would definitely stay again. "
Cape Cod Inn
Hyannis Plaza Hotel
2.5 star property
6.8 out of 10, (672)
"I paid online for the weekend and then an additional amount that I didn’t know about when checking in and I was told that it would be back in my account Monday morning and have not received it yet. "
The price is SAR 286
SAR 359 total
includes taxes & fees
26 Nov - 27 Nov
Hyannis Plaza Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's Main Street Hyannis like for family-friendly vacations?
The walkable destination of Main Street Hyannis is a good choice if you’ve been thinking about a trip with your kids. The beaches, excursions, and local tours are just some of the things that make this the perfect spot for family trips. Take to the air and fly into Hyannis, MA (HYA-Barnstable Municipal), which is the closest airport, or Vineyard Haven, MA (MVY-Martha’s Vineyard), which is located 24.9 mi (40 km) from the city center.
What's the best accommodation when traveling with kids to Main Street Hyannis?
Americas Best Value Inn & Suites Hyannis Cape Cod is a hotel with an indoor pool and free parking, and it’s a top choice on Expedia for families.
How many family-friendly hotels will I find in Main Street Hyannis?
Expedia has 6 family-friendly hotels and other accommodations in Main Street Hyannis.
When's the best time to book a family-friendly vacation in Main Street Hyannis?
The hottest months are usually August and July with an average temp of 67°F, while the coldest months are February and January with an average of 37°F. Average annual precipitation for Main Street Hyannis is 52 inches.
What's there to see and do with your family in Main Street Hyannis?
While you are visiting Main Street Hyannis, you and the family might want to check out some interesting spots such as Wackenhammer’s Clockwork Arcade, Hyannis Harbor, and Cape Cod Melody Tent. Make sure you have lots of time for activities like Cape Codder Water Park and Cape Cod Inflatable Park.