Photo by Ronald Wilson

Search Vacation Homes in Lake City

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Compare 126 Vacation Homes in Lake City with updated reviews, rates, and availability.

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

9.8 out of 10, Exceptional, (74)
"Great overall "
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

10.0 out of 10, Exceptional, (31)
"It was a great experience. "
The price is SAR 559
SAR 1,042 total
includes taxes & fees
6 Dec - 7 Dec
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Quaint rural downtown community close to springs, 3 rivers, biking & equestrian

9.2 out of 10, Wonderful, (36)
"Very comfortable home and super comfortable bed. Our host did a great job and responded pretty quick with any questions we had. "
Quaint rural downtown community close to springs, 3 rivers, biking & equestrian

"FLOATS MY BOAT"- Suwannee River Home in Branford, FL, near area Springs, too!

10.0 out of 10, Exceptional, (59)
"Amazing views, peaceful!!.great location"
"FLOATS MY BOAT"- Suwannee River Home in Branford, FL, near area Springs, too!

Renovated cozy cottage, pet friendly, close to Springs, sleeps 8

9.6 out of 10, Exceptional, (22)
"Great weekend in a quiet neighborhood. Peaceful and comfortable. "
Renovated cozy cottage, pet friendly, close to Springs, sleeps 8

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

10.0 out of 10, Exceptional, (13)
"Myself and a few friends were here from all over to help with the hurricane disaster relief project. Mrs. Christine made sure we were comfortable, made accommodations for us, and had exceptional hospitality. You will love it here!!!!!"
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

9.4 out of 10, Exceptional, (53)
"We have stayed at margaritaville once before we really enjoy the property and cabin! Unfortunately the River was flooded and the kayaks weren’t in the best condition for such an intense River. Over all we had a blast. The second floor was perfect for the teenage boys to have some privacy and fun. We had everything we need to have awesome family dinners and our pets we’re safe and in heaven!"
The price is SAR 747
SAR 1,622 total
includes taxes & fees
3 Dec - 4 Dec
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

10.0 out of 10, Exceptional, (10)
"We loved our stay. The property is so clean and was the best equipped VRBO we have ever stayed in. It was great for being close the the springs and some great did and breweries just a short drive away. We will be staying again. Host was great to work with."
Pet-Friendly Florida Escape w/ Patio & Fire Pit!

6+ Sleeper Farm Escape with HUGE Yard and RV Hookup is Out Standing in its Field

10.0 out of 10, Exceptional, (28)
"We came here to evacuate from a hurricane . This house came with everything and then some that was needed . The house is huge and clean . "
6+ Sleeper Farm Escape with HUGE Yard and RV Hookup is Out Standing in its Field

Modern & Convenient 3/2 Home

10.0 out of 10, Exceptional, (6)
"My granddaughter got married in Live Oak and the venue was not far away from us. It was a great location, great value and very quiet neighborhood. Since we had a teenager with us thank goodness for great Wi-Fi connection. I would recommend this house to any family. Thank you for letting us stay! SM and Family"
Modern & Convenient 3/2 Home

Serene, Luxurious Riverside Home – Dock + Hot Tub!

8.4 out of 10, Very Good, (8)
"From the moment we arrived at this property we were disappointed. So many things were completely unacceptable. Just to list a few. Not enough towels for everyone. The water here is brown. You will need to bring drinking and cooking water. Dead and live bugs in the house. Fridge downstairs was filthy. The couch is broken in several spots. Cigarette butts and trash in the yard. The hot tub was not turned on. So we could not use for 2 days until it warmed. All of the toilets were not cleaned!! I...
Serene, Luxurious Riverside Home – Dock + Hot Tub!

Historic Spring Cottage -Sleeps 5, Pets welcome!

10.0 out of 10, Exceptional, (5)
"Cozy little cottage and even better hospitality from the host. "
The price is SAR 843
SAR 1,539 total
includes taxes & fees
30 Nov - 1 Dec
Historic Spring Cottage -Sleeps 5, Pets welcome!

Luxurious Stay overlooking the beautiful Suwannee River! 3 bed/3 bath House!

2.0 star property
10.0 out of 10, Exceptional, (4)
"The house was decorated nicely and clean. Lovely weather to sit outside and drink coffee. Very peaceful. "
Luxurious Stay overlooking the beautiful Suwannee River! 3 bed/3 bath House!

Affordable 3-bedroom house in fabulous Gainesville with AC, WiFi

2.0 star property
10.0 out of 10, Exceptional, (2)
"Met all our needs and everything you may need to is within 15.mins by car. If staying for a longer period you will need to find a Laundromat as the property does not have a washer and dryer"
The price is SAR 300
SAR 1,364 total
includes taxes & fees
1 Dec - 2 Dec
Affordable 3-bedroom house in fabulous Gainesville with AC, WiFi

Cozy beautiful house with new modern design

8.0 out of 10, Very Good, (13)
"Great location to Ben Hill Griffin Stadium. Home was clean and met the needs of my husband and son who traveled for a Gator game. Hostess was very responsive."
Cozy beautiful house with new modern design

Beautiful home 10 minutes from Gilchrist Blue Springs State Park

9.6 out of 10, Exceptional, (20)
"Host was very accommodating and house was great. "
The price is SAR 375
SAR 950 total
includes taxes & fees
2 Dec - 3 Dec
Beautiful home 10 minutes from Gilchrist Blue Springs State Park

Fishing Paradise w/ Deck On Suwannee River

9.2 out of 10, Wonderful, (27)
"Wonderful host!"
Fishing Paradise w/ Deck On Suwannee River

New riverfront home across from Rock Bluff Springs on the Suwannee river

10.0 out of 10, Exceptional, (24)
"We reserved the property for a weekend getaway to take our friends boys on the Suwannee River. These guys were so excited to go on the air boat and thought the property we stayed in was on point! The host were exceptional and very communitive. The home was quality built and perfect. The morning breakfast on the large deck over looking the river was a big hit. We would recommend this property and would stay here again. It was a 5 star experience. Thank you for your professionalism and letting us...
New riverfront home across from Rock Bluff Springs on the Suwannee river

Bunkhouse Farm Stay

10.0 out of 10, Exceptional, (123)
"Peaceful and beautiful. My daughter and I loved our stay here. We wish we had more time there as we were gone almost all day with softball. If we com back to the area we will definitely stay again."
Bunkhouse Farm Stay

Custom Built Home steps from the Santa Fe River

10.0 out of 10, Exceptional, (65)
"Beautiful, clean house! WiFi doesn’t work well but great location to visit many local springs. Owner was very communicative. Perfect end of summer trip."
Custom Built Home steps from the Santa Fe River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Lake City
Save an average of 15% on thousands of hotels when you're signed in

Other property types in Lake City

Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

8.4 out of 10, Very Good, (41)
"Host was very friendly & accomodating, flexible. Long, dusty, bumpy dirt road to property. Woodsy & secluded. If you think camping, you'll be thrilled w/ AC, very comfortable beds, electricity, hot & cold water etc. You won't mind so much missing & broken items and minor housekeeping lapses. Overall, a pleasant, inexpensive getaway, tho you can hear &glimpse major highway nearby. Despite nearby homes, we saw a deer and several bunnies!"
The price is SAR 300
SAR 688 total
includes taxes & fees
26 Nov - 27 Nov
Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style

O'LE LADYBUG COTTAGE

9.8 out of 10, Exceptional, (42)
"The cottage was everything that we wanted and needed. It is out in the country but close enough to stores if we wanted to go out. Everything is so quiet there. You could hear no traffic or neighbors. It was very peaceful."
The price is SAR 409
SAR 846 total
includes taxes & fees
2 Dec - 3 Dec
O'LE LADYBUG COTTAGE

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

10.0 out of 10, Exceptional, (31)
"It was a great experience. "
The price is SAR 559
SAR 1,042 total
includes taxes & fees
6 Dec - 7 Dec
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.