Photo by Ronald Wilson
Find Business Hotels in Lake City, FL
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Lake City Business Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare Lake City Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites Lake City
Fairfield Inn & Suites Lake City
9.2 out of 10, Wonderful, (78)
The price is SAR 428
SAR 482 total
includes taxes & fees
17 Apr - 18 Apr

Holiday Inn Express Hotel & Suites LIVE OAK by IHG
Holiday Inn Express Hotel & Suites LIVE OAK by IHG
8.4 out of 10, Very Good, (678)
The price is SAR 417
SAR 459 total
includes taxes & fees
27 Apr - 28 Apr

Holiday Inn & Suites Lake City by IHG
Holiday Inn & Suites Lake City by IHG
8.6 out of 10, Excellent, (1003)
The price is SAR 379
SAR 427 total
includes taxes & fees
27 Apr - 28 Apr

Comfort Suites Lake City
Comfort Suites Lake City
9.6 out of 10, Exceptional, (1002)
The price is SAR 437
SAR 492 total
includes taxes & fees
23 Apr - 24 Apr

Best Western Plus Lake City
Best Western Plus Lake City
9.2 out of 10, Wonderful, (1004)
The price is SAR 378
SAR 425 total
includes taxes & fees
13 Apr - 14 Apr

Quality Inn & Suites Live Oak I-10 Exit 283
Quality Inn & Suites Live Oak I-10 Exit 283
7.0 out of 10, Good, (474)
The price is SAR 392
SAR 431 total
includes taxes & fees
29 Apr - 30 Apr

Hampton Inn & Suites Lake City
Hampton Inn & Suites Lake City
9.4 out of 10, Exceptional, (944)
The price is SAR 420
SAR 473 total
includes taxes & fees
20 Apr - 21 Apr

Baymont by Wyndham Lake City
Baymont by Wyndham Lake City
5.2 out of 10, (998)
The price is SAR 230
SAR 258 total
includes taxes & fees
27 Apr - 28 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Lake City
Find out more about Lake City
Recent reviews of Lake City hotels
Recent reviews of Lake City hotels

Baymont by Wyndham Lake City
5/5 Excellent
"This property is in a great location! Lots of beaches clae by. World class fishing! The kids absolutly loved the pool. Morning coffee & sunrises where beautiful. Lots of wildlife around the water! I would defintly stay again. All questions & communication was prompt! "
A verified traveler stayed at Baymont by Wyndham Lake City
Posted 3 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
More Hotel Options in Lake City
- Adventure Hotels in Lake City
- Beach Hotels in Lake City
- Casinos in Lake City
- Cheap Hotels in Lake City
- Family Hotels in Lake City
- Golf Hotels in Lake City
- Historic Hotels in Lake City
- Hotels with Bars in Lake City
- Hotels with Free Parking in Lake City
- Hotels with Hot Tubs in Lake City
- Hotels with WiFi in Lake City
- Hotels with a Pool in Lake City
- Hotels with an Indoor Pool in Lake City
- Hotels with smoking rooms in Lake City
- Luxury Hotels in Lake City
- Pet-friendly Hotels in Lake City
- Resorts & Hotels with Spas in Lake City
- Romantic Hotels in Lake City
- Shopping Hotels in Lake City
- Ski Hotels in Lake City
More Accommodation Types in Lake City
- Vacation Homes in Florida
- Condo Rentals in Florida
- Apartments in Florida
- Villas in Florida
- Cottages in Florida
- Resorts in Florida
- Aparthotels in Florida
- Motels in Florida
- Guest Houses in Florida
- Cabin Rentals in Florida
- B&B in Florida
- Houseboats in Florida
- Town Houses in Florida
- RV Parks in Florida
- Farmstay in Florida
- Condo Resorts in Florida
- Lodges in Florida
- Hostels in Florida
- Chalets in Florida
- Residences in Florida
- Holiday Park Resorts in Florida
- Inns in Florida
- Country Houses in Florida
Hotels near popular Lake City Attractions
- Hotels near Southside Sports Complex
- Hotels near Southside Recreation Complex
- Hotels near North Florida Speedway
- Hotels near Lake City Mall
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Columbia County Courthouse
- Hotels near Florida Department of Transportation
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Lake DeSoto Farmers Market
- Hotels near Pine Grove Baptist Church
Lake City Hotels by Star Rating
Explore more hotels
- Fairfield Inn & Suites Lake City
- Hampton Inn & Suites Lake City
- Palms Garden Inn
- Baymont by Wyndham Lake City
- Home2 Suites by Hilton Lake City
- Days Inn by Wyndham Lake City I-10
- Gateway Inn
- Knights Inn Lake City
- Regal Inn
- The Blanche
- Super 8 by Wyndham Lake City
- Econo Lodge Lake City-North
- Rodeway Inn Lake City I-75
- Private&Secluded Getaway, near I-75,town, parks,Springs. Glamping ,low key style
- Vista Verde Farm Retreat
- Driftwood Inn
- Modern & Convenient 3/2 Home
- Best Western Gateway Grand
- Quality Inn Alachua - Gainesville Area
- Holiday Inn Express Hotel & Suites LIVE OAK by IHG