Photo by Ronald Wilson

Find Luxury Hotels in Lake City, FL

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Check availability on Lake City Luxury Hotels

Compare Lake City Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (525)
"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."
The price is SAR 251
SAR 283 total
includes taxes & fees
23 Mar - 24 Mar
Palms Garden Inn

Americas Best Value Inn Lake City

2.0 star property
8.8 out of 10, Excellent, (1004)
"The staff was super nice, the rooms were extremely clean, and the beds were super comfy!! This will be my place to stop when traveling to Lake City. "
The price is SAR 315
SAR 354 total
includes taxes & fees
31 Mar - 1 Apr
Americas Best Value Inn Lake City

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (727)
"This was a bare bones hotel. The room was clean and the beds were comfortable. There was Wi-Fi and a tv, and not much else. If all you want is a comfortable bed, then this is the place for you. "
The price is SAR 270
SAR 304 total
includes taxes & fees
24 Mar - 25 Mar
Driftwood Inn

Econo Lodge Lake City-North

2.0 star property
6.8 out of 10, (385)
"Great staff"
The price is SAR 280
SAR 315 total
includes taxes & fees
27 Mar - 28 Mar
Econo Lodge Lake City-North

Comfort Suites Lake City

2.5 star property
9.6 out of 10, Exceptional, (1001)
"Property was clean. Nice staff"
The price is SAR 426
SAR 479 total
includes taxes & fees
23 Mar - 24 Mar
Comfort Suites Lake City

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1000)
"Clean, well priced, close to interstate "
The price is SAR 271
SAR 305 total
includes taxes & fees
23 Mar - 24 Mar
Days Inn by Wyndham Lake City I-10

Super 8 by Wyndham Lake City

2.0 star property
7.0 out of 10, Good, (596)
"Nice stay and light the free supper, and eggs in the morning, the Wister with some meat selection. People were friendly but my only complaint would be the thin walls between the guest rooms. I could hear my neighbor and his TV playing 24/7 over 3 days"
The price is SAR 331
SAR 372 total
includes taxes & fees
23 Mar - 24 Mar
Super 8 by Wyndham Lake City

Rodeway Inn Lake City I-75

2.0 star property
6.6 out of 10, (370)
"quite "
The price is SAR 246
SAR 277 total
includes taxes & fees
26 Mar - 27 Mar
Rodeway Inn Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in Lake City?
Use Expedia to arrange your flight to Gainesville Regional Airport (GNV) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Lake City has to offer. While you’re visiting, you might want to think about enjoying the festivals and sporting events, which Lake City is known for.
How many luxury hotels will I find in Lake City?
Lie in the lap of luxury during your getaway to Lake City in one of Expedia’s 12 luxury hotels.
When can I expect good weather in Lake City?
Planning for the weather is an important factor for making your trip to Lake City a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Lake City is 51 inches.
What's there to see and do in Lake City?
When you’re in Lake City, enjoy exploring the sights and attractions here including Columbia County Courthouse, Florida Department of Transportation, and Southside Recreation Complex. If you have spare time during your trip, you might want to make a stop at Southside Sports Complex and Lake City Mall.