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- Holiday Inn Express Brevard City Center, an IHG Hotel
- Tru by Hilton Seneca Clemson
- Holiday Inn Express & Suites Clemson, an IHG Hotel
- Grayling Cottage | Gorgeous Cottage just one block from Main Street
- Days Inn by Wyndham Clemson
- Hampton Inn & Suites Seneca-Clemson Area
- Clemson University's James F. Martin Inn
- Highlander Mountain House
- The Inn at Patrick Square
- Outpost Inn
- Tripps Cabin- Quaint cabin a mile from downtown Highlands!
- NEW! Movie Theater, Pool Table, Hot Tub and MORE in Bear Lake Reserve!!
- Comfort Inn & Suites
- Foxhunt at Sapphire Valley by Capital Vacations
- Greystone Inn
- Postcard Cabins Lake Hartwell
- Hotel Cashiers
- The Wells Cashiers
- Unique Waterfall Chalet, Decks Over Huge Waterfall in the Nantahala! Pets OK!
- 1930's Highlands Hideaway, Restored Cozy Cabin, Dog Friendly, Fiber Optic WI-FI