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Find Resorts & Hotels with Spas in Odessa, FL

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Check availability on Odessa Resorts & Hotels with Spas

Compare Odessa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn Odessa Trinity
Exterior

Hampton Inn Odessa Trinity

2.5 star property
9.6 out of 10, Exceptional, (826)
"Location to everything!"
The price is SAR 571
SAR 639 total
includes taxes & fees
23 Feb - 24 Feb
Hampton Inn Odessa Trinity
Holiday Inn Express & Suites Trinity by IHG
Room

Holiday Inn Express & Suites Trinity by IHG

2.5 star property
9.0 out of 10, Wonderful, (632)
"This location was near Trinity Hospital, lots of shops and restaurants, and easy to find. The building is dated, but clean and comfortable. Great customer service!"
The price is SAR 558
SAR 625 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express & Suites Trinity by IHG
8 Mi to Tarpon Springs Sponge Docks: Home w/ Grill
Odessa Vacation Rental | 5BR | 2BA | 2,400 Sq Ft | Step-Free Access

8 Mi to Tarpon Springs Sponge Docks: Home w/ Grill

8 Mi to Tarpon Springs Sponge Docks: Home w/ Grill
Adorable Waterfront Cottage
Terrace/patio

Adorable Waterfront Cottage

9.8 out of 10, Exceptional, (12)
"Michael was very understanding when my partner and I made a decision upon arrival that the property just wasn’t what we had in mind or for us. He immediately communicated with Vrbo about seeing if I could get a refund, offered to connect us with a brother who has several rentals, and just could not have been more Understanding and mature. That’s why he gets the excellent ratings he gets."
Adorable Waterfront Cottage
The Robins Nest|Lakefront Home w/ Pool & Theater
Make lasting memories on our private dock!

The Robins Nest|Lakefront Home w/ Pool & Theater

The Robins Nest|Lakefront Home w/ Pool & Theater
2 kitchens, Canoe, kayak on Sunset Lake + 700sqf apt Perfect for family getaways
Get our canoe for a peaceful short stroll to Sunset lake

2 kitchens, Canoe, kayak on Sunset Lake + 700sqf apt Perfect for family getaways

8.4 out of 10, Very Good, (24)
"We truly enjoyed our stay. It was wonderful. We loved taking the dogs out in the canoe on the lake. We grilled every night and even enjoyed a fire in the fire pit. It was so quiet and exactly the get away we needed."
2 kitchens, Canoe, kayak on Sunset Lake + 700sqf apt Perfect for family getaways
Charming cottage in old Florida Odessa lake community with AC, WiFi, kayak
Room

Charming cottage in old Florida Odessa lake community with AC, WiFi, kayak

9.4 out of 10, Exceptional, (3)
"Not knowing the area at all, I couldn’t have picked anything better. The property was perfect. The house was both cozy and charming and traveling alone, very safe. Thank-you very much for sharing your home with me!"
Charming cottage in old Florida Odessa lake community with AC, WiFi, kayak
Odessa Lakeside: 3BR Pool & Hot Tub

Odessa Lakeside: 3BR Pool & Hot Tub

Odessa Lakeside: 3BR Pool & Hot Tub
Five Star Rating Lake/WaterFront Oasis Near Tampa/Orlando & Gulf Beaches
Beach

Five Star Rating Lake/WaterFront Oasis Near Tampa/Orlando & Gulf Beaches

10.0 out of 10, Exceptional, (35)
"This lakehouse was perfect!!! Beautiful renovation of a mid-century build. Modern appliances. Adorable decor. Hot water for days under lux showerhead. Well stocked kitchen. View amazing. Appreciated the use of kayaks. Great neighbor. Would stay again in a heartbeat. "
Five Star Rating Lake/WaterFront Oasis Near Tampa/Orlando & Gulf Beaches
Luxurious Home w/ Private Pool & Lanai Near Tampa!
Odessa Vacation Rental | 3BR | 4BA | 3,500 Sq Ft | Stairs Required

Luxurious Home w/ Private Pool & Lanai Near Tampa!

9.6 out of 10, Exceptional, (17)
"From start to finish, our 8-day stay in Cleo and John's home was perfect. The booking was easy and communication about the property and its details was prompt and clear. The home is beautifully furnished and spacious. Its layout is perfectly configured and our family of 5 (4 of whom were "working" from home) had plenty of room, both inside and outdoors in the beautiful lenai. The fully equipped kitchen was stocked with our favorite food basics which made our first breakfast after a late night...
Luxurious Home w/ Private Pool & Lanai Near Tampa!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Odessa?
Soothe the senses with some time in one of our wonderful spa hotels. Check out the lakeside setting in Odessa - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
How many spa hotels are there in Odessa?
Among Expedia’s 26 accommodation options in Odessa, there is 1 spa hotel.
What's there to see and do in Odessa?
Enjoy Odessa with a stop at Crescent Lake, Keystone Lake, and Silver Dollar Golf Club. If you have extra time while you’re in the area, you might want to see The Eagles Golf Club and Old McMicky’s Farm.
What is a Odessa spa hotel?
Spa hotels in Odessa have full on-site spas and offer services like therapies and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.