Find Resorts & Hotels with Spas in Mission, TX

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Pick from 16 Mission Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Holiday Inn Express Hotel & Suites Mission-McAllen Area, an IHG Hotel
Exterior
Holiday Inn Express Hotel & Suites Mission-McAllen Area, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (850)
"Great hotel, very comfortable, very clean. Breakfast was good. The only thing i didnt like was the smell of the room, it had a bleachy smell that was quite annoying. "
The price is SAR 376
SAR 418 total
includes taxes & fees
10 Nov - 11 Nov
Holiday Inn Express Hotel & Suites Mission-McAllen Area, an IHG Hotel
La Quinta Inn & Suites by Wyndham Mission at West McAllen
Exterior
La Quinta Inn & Suites by Wyndham Mission at West McAllen
2.5 star property
8.0 out of 10, Very Good, (1000)
"Just breakfast was not as good as on the other hotels I have stayed in McAllen "
The price is SAR 303
SAR 337 total
includes taxes & fees
11 Nov - 12 Nov
La Quinta Inn & Suites by Wyndham Mission at West McAllen
SureStay Hotel By Best Western Mission
Pool
SureStay Hotel By Best Western Mission
2.5 star property
7.6 out of 10, Good, (463)
"Economically priced and free breakfast"
The price is SAR 169
SAR 188 total
includes taxes & fees
10 Dec - 11 Dec
SureStay Hotel By Best Western Mission
Hampton Inn & Suites Mission
Exterior
Hampton Inn & Suites Mission
2.5 star property
8.8 out of 10, Excellent, (1002)
"Everything,i’ll be back soon😉"
The price is SAR 330
SAR 368 total
includes taxes & fees
1 Dec - 2 Dec
Hampton Inn & Suites Mission
Motel 6 Mission, TX
Exterior
Motel 6 Mission, TX
2.0 star property
7.8 out of 10, Good, (1001)
"Enjoy my whole stay there."
The price is SAR 199
SAR 225 total
includes taxes & fees
10 Nov - 11 Nov
Motel 6 Mission, TX
The Bungalows on Shary, Mission-McAllen
Property amenity
The Bungalows on Shary, Mission-McAllen
2.5 star property
8.4 out of 10, Very Good, (794)
"The site as well as the room meets the Saryland expectations, we will definitely book again "
The price is SAR 470
SAR 520 total
includes taxes & fees
10 Dec - 11 Dec
The Bungalows on Shary, Mission-McAllen
Shary Inn and Suites
Exterior
Shary Inn and Suites
2.5 star property
8.4 out of 10, Very Good, (572)
"This was my 2nd time with this facility. Both times the first room I was assigned had to be changed, this time it was just because there was no remote for the TV and they did not have a replacement available. Not a major issue just a small annoyance The next room was clean and fully ready. The lobby area is always clean and in good repair. The complimentary breakfast was very good, only issue they had run out of the sausage gravy and biscuits which is one of my favorite breakfast items. ...
The price is SAR 209
SAR 232 total
includes taxes & fees
25 Nov - 26 Nov
Shary Inn and Suites
VINTAGE MEETS MODERN IN LARGE HOUSE W/POOL!
Exterior
VINTAGE MEETS MODERN IN LARGE HOUSE W/POOL!
9.6 out of 10, Exceptional, (14)
"Property OK, kitchen cleanliness disappoints, lacks dishwasher, kitchen cabinets and some furniture requires maintenance. "
VINTAGE MEETS MODERN IN LARGE HOUSE W/POOL!
The Cozy Houz at Cimarron! With Golf Course View
Dining
The Cozy Houz at Cimarron! With Golf Course View
9.8 out of 10, Exceptional, (17)
"Great place to stay. Very close to everything and very clean. Will definitely stay again if I’m back in the area "
The Cozy Houz at Cimarron! With Golf Course View
Spacious 4BR and 5RR Spanish Hacienda with Private Pool
Pool
Spacious 4BR and 5RR Spanish Hacienda with Private Pool
9.2 out of 10, Wonderful, (7)
"Good "
Spacious 4BR and 5RR Spanish Hacienda with Private Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Mission?
Forget the stress of everyday life and book yourself a lush spa hotel. Check out the entertainment choices and shopping in Mission—your day trip starts here. Enjoy the live music and many popular restaurants during your vacation. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Mission?
Among Expedia’s 26 accommodation options in Mission, there is 1 spa hotel.
What's there to see and do in Mission?
Take in the sights and attractions that Mission offers with a visit to Rio Grande, Bentsen-Rio Grande Valley State Park, and Anzalduas Park. If you have a little extra time during your trip, you might want to make a stop at Shary Municipal Golf Course and National Butterfly Center.
What is a Mission spa hotel?
Spa hotels in Mission provide lodging and have an on-site spa offering services like massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.