Find Resorts & Hotels with Spas in Mira Mesa, CA

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Check availability on Mira Mesa Resorts & Hotels with Spas

Compare Mira Mesa Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Super Spacious Family Vacation Home!

9.4 out of 10, Exceptional, (13)
"Loved the house, great stay and would recommend to others"
The price is SAR 1,309
SAR 2,438 total
includes taxes & fees
25 May - 26 May
Super Spacious Family Vacation Home!

Town house 3Bdr/2.5Br Fully furnished Rancho Peñasquitos area of San Diego

9.6 out of 10, Exceptional, (53)
"A true hidden gem in a convenient but quiet neighborhood. Will stay again."
Town house 3Bdr/2.5Br Fully furnished Rancho Peñasquitos area of San Diego

Super cute modern studio with private entrance!

9.4 out of 10, Exceptional, (3)
"I came to visit my son and daughter-in-law who live close by in Mira Mesa. The place was exactly as advertised- very clean, comfortable bed and had all needed amenities. Will definitely book again when I travel here!"
The price is SAR 341
SAR 1,072 total
includes taxes & fees
4 May - 5 May
Super cute modern studio with private entrance!

Bright Cozy 3b/2b with nice backyard & BBQ

10.0 out of 10, Exceptional, (13)
"Great property. We liked how comfortable the beds were and how quiet the neighborhood was. We'd stay there again."
Bright Cozy 3b/2b with nice backyard & BBQ

New Stylish Stay Mira Mesa home W/Game Room Fun Near All Hot Spots of San Diego!

10.0 out of 10, Exceptional, (1)
"My family absolutely loved it! It was just as it was in the pictures on the app and more. There was lots of entertainment for the kiddos and the neighborhood was quiet and seemed to be pretty safe over all. We will be staying here next time."
New Stylish Stay Mira Mesa home W/Game Room Fun Near All Hot Spots of San Diego!

Charming Family 3BR w/ Game Room

Charming Family 3BR w/ Game Room

Remodeled Urban Retreat Self Check-In, Hot Tub, Foosball, Fire Pit, Cornhole

Remodeled Urban Retreat Self Check-In, Hot Tub, Foosball, Fire Pit, Cornhole
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Mira Mesa?
Forget the stress of everyday life and book yourself a hotel with a spa. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Mira Mesa?
Among Expedia’s 18 accommodation options in Mira Mesa, there is 1 spa hotel.
What's there to see and do in Mira Mesa?
Enjoy Mira Mesa and visit Mission Bay, San Diego Zoo, and San Diego Zoo Safari Park. If you have spare time during your trip, you might want to make a stop at Mission Beach and Marine Corps Recruit Depot.
What is a Mira Mesa spa hotel?
Spa hotels in Mira Mesa provide lodging and have an on-site spa offering services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.