Find Resorts & Hotels with Spas in Depew, NY

Pick from 2 Depew Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Frequently asked questions

Looking for a spa hotel in Depew?
Treat yourself to some pampering and book a hotel with a spa. Check out the waterfalls in Depew - worth a picture or two! Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your holiday.
How many spa hotels will I find in Depew?
Among Expedia’s 4 accommodation options in Depew, there is 1 spa hotel.
What's there to see and do in Depew?
Enjoy Depew and visit KeyBank Center, Holiday Twin Rinks, and Walden Galleria Mall. If you have some spare time during your trip, you might want to check out Samuel’s Grande Manor and Glen Falls.
What is a Depew spa hotel?
Spa hotels in Depew feature full on-site spas and offer services like facials and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.