Photo by Jessica King

Find hotels in De Soto, MO from SAR 191

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Compare 146 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Club Vacations Timber Creek Resort at De Soto

3.5 star property
9.4 out of 10, Exceptional, (139)
"Many things to do if you don't want to go anywhere. Close to shopping, restaurant. "
The price is SAR 596
SAR 687 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Club Vacations Timber Creek Resort at De Soto

The Conner House B&B

3.5 star property
10.0 out of 10, Exceptional, (13)
"Conner House is without parallel in the area - it stands alone by setting a relaxed yet elegant standard. We're treated beyond courtesy and civility with genuine respect and warmth. We've stayed here before and will likely do so again."
The price is SAR 586
SAR 650 total
includes taxes & fees
23 Feb - 24 Feb
The Conner House B&B

Corner George Inn Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (151)
"I was traveling to a 50th high school reunion, and Corner George Inn Bed & Breakfast was just a few steps away. Good breakfast, and comfortable lodgings."
The price is SAR 482
SAR 535 total
includes taxes & fees
25 Feb - 26 Feb
Corner George Inn Bed & Breakfast

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (2)
"This place made me look like a rockstar to my wife. I surprised her with a V day getaway. The cabin was awesome. We loved the view of nature from the large window. I made dinner reservations nearby at the weingarten vineyard. The hiking trail along the creek was fun. We ate breakfast right down the road at Kozy. For our final night I cooked steaks over the open fire"
The price is SAR 300
SAR 323 total
includes taxes & fees
3 Mar - 4 Mar
Postcard Cabins St. Francois

Tiny Houses of French Village

2.5 star property
10.0 out of 10, Exceptional, (2)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
The price is SAR 926
SAR 1,372 total
includes taxes & fees
23 Feb - 24 Feb
Tiny Houses of French Village

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1000)
"My boyfriend and I enjoyed the Jacuzzi and the room. Plus, it was very quiet where we were."
The price is SAR 456
SAR 527 total
includes taxes & fees
2 Mar - 3 Mar
Drury Inn & Suites St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1005)
"It was nice and quiet. "
The price is SAR 321
SAR 371 total
includes taxes & fees
26 Feb - 27 Feb
Pear Tree Inn St. Louis Arnold

WoodSpring Suites St. Louis Arnold

2.5 star property
6.0 out of 10, (387)
"Everything "
The price is SAR 266
SAR 308 total
includes taxes & fees
23 Feb - 24 Feb
WoodSpring Suites St. Louis Arnold

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

2.5 star property
8.0 out of 10, Very Good, (748)
"Love everything about our stay we will definitely be back"
The price is SAR 357
SAR 408 total
includes taxes & fees
26 Feb - 27 Feb
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Quality Inn Festus

3.0 star property
6.8 out of 10, (893)
"Room and bathroom were clean, our room’s carpet had holes and was ripped up by the AC the room smelled moldy. Employees were polite"
The price is SAR 334
SAR 382 total
includes taxes & fees
1 Mar - 2 Mar
Quality Inn Festus

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (781)
"Comfortable room that was clean except bureau and desk tops which were smeared with some kind of cleaner and not wiped off. Had to use handiwipes to clean up. Nothing special about hotel or breakfast."
The price is SAR 322
SAR 377 total
includes taxes & fees
24 Feb - 25 Feb
Comfort Inn Festus - St Louis South

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (618)
"It was clean and reasonably priced. The employees were friendly and kind. "
The price is SAR 521
SAR 596 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (477)
"I liked the property. I objected to the pet fee of $75.00 per night!! That was half of the price of the room! It was late and we were very tired, but I will check into the pet fee policy at Hampton Inn before staying at one again."
The price is SAR 521
SAR 593 total
includes taxes & fees
23 Feb - 24 Feb
Hampton Inn Farmington

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (405)
"The staff were absolutely the kindest people. Enjoyed the complementary breakfast each morning. The hotel itself was mostly clean but is starting to look a little aged. We had major rain and several leaking areas. Also were super excited to have an indoor pool available but the water was SO COLD even for my rambunctious 5 year old. 😅"
The price is SAR 382
SAR 1,033 total
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn Express & Suites Farmington by IHG

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (515)
"Was great"
The price is SAR 226
SAR 257 total
includes taxes & fees
23 Feb - 24 Feb
Super 8 by Wyndham Farmington

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (857)
"Exceeded my expectations for the price. Good breakfast"
The price is SAR 210
SAR 239 total
includes taxes & fees
1 Mar - 2 Mar
Baymont Inn and Suites by Wyndham Farmington, MO

Quality Inn Farmington

2.5 star property
7.8 out of 10, Good, (776)
"Was awesome. Actuay far exeded my expectations. In whole dude to the unbelivable beautiful soul they have atcthe front desk. They finaly got it right with the switch of staf. Farmington finaly has some better more welcoming people to greet them now. The Quality Inn. Top Notch."
The price is SAR 191
SAR 228 total
includes taxes & fees
16 Mar - 17 Mar
Quality Inn Farmington

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (515)
"Nice older rooms. Comfy beds and a gorgeous view facing golf course. Staff was absolutely amazing and super friendly. We had a jet tub in our room and it was just what we needed. "
The price is SAR 435
SAR 496 total
includes taxes & fees
9 Mar - 10 Mar
Crown Pointe Lodge, BW Signature Collection

Rosener's Inn and banquet center

2.0 star property
5.0 out of 10, (48)
" I arrived at 5:30 the office was closed even though it said it closed at 6 PM. I called I could hear the phone ringing but no one answered the phone and there was no opportunity to leave a message. I had to find another hotel to spend the night, apparently they are not interested in running a business "
The price is SAR 202
SAR 226 total
includes taxes & fees
15 Mar - 16 Mar
Rosener's Inn and banquet center

Super 8 by Wyndham Bonne Terre

2.0 star property
6.8 out of 10, (445)
"What can be said. It is a Super 8. Essentially the closest hotel to the Bonne Terre Mine, where we were going to be diving. The room was adequate. There was a hole in the blanket, but didn't affect its function. I really can't complain considering the reasonably cheap price. "
The price is SAR 198
SAR 216 total
includes taxes & fees
24 Mar - 25 Mar
Super 8 by Wyndham Bonne Terre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

Frequently asked questions

Where is the best place to stay in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto is one of the top choices for your stay based on our traveler data. This aparthotel offers free parking and private balconies. Other good options for your visit to the area are Pear Tree Inn St. Louis Arnold and Baymont Inn and Suites by Wyndham Farmington, MO. See all available top hotels, or vacation rentals in De Soto.

What are some of the best vacation rentals that De Soto has to offer?

Cute spacious Ranch - very safe area - 4 BR 2B- big fenced yard -1800 sft : This vacation home rental near De Soto has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.

What's the best pet-friendly hotel in De Soto?
What are some accommodations with pools in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto: Features 2 outdoor tennis courts, a seasonal outdoor pool, and a sauna. Pear Tree Inn St. Louis Arnold and Baymont Inn and Suites by Wyndham Farmington, MO are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.

What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 7 hotels and other accommodations to choose from. Find out more about De Soto.

What should I do while I'm visiting De Soto?

Natural beauty is on display at Washington State Park, Big River, and Sunrise Lake Beach. A couple of additional sights to add to your agenda are Valle Lake Beach and Big Lake. Check out what more to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.