Photo by Jessica King

Find hotels in De Soto, MO from SAR 191

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Compare 159 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Conner House B&B

3.5 star property
10.0 out of 10, Exceptional, (13)
"Conner House is without parallel in the area - it stands alone by setting a relaxed yet elegant standard. We're treated beyond courtesy and civility with genuine respect and warmth. We've stayed here before and will likely do so again."
The price is SAR 487
SAR 540 total
includes taxes & fees
14 Apr - 15 Apr
The Conner House B&B

Corner George Inn Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (151)
"Hosts were excellent, very quiet and the breakfast was wonderful"
The price is SAR 483
SAR 536 total
includes taxes & fees
15 Apr - 16 Apr
Corner George Inn Bed & Breakfast

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (3)
"This place made me look like a rockstar to my wife. I surprised her with a V day getaway. The cabin was awesome. We loved the view of nature from the large window. I made dinner reservations nearby at the weingarten vineyard. The hiking trail along the creek was fun. We ate breakfast right down the road at Kozy. For our final night I cooked steaks over the open fire"
The price is SAR 338
SAR 364 total
includes taxes & fees
27 Apr - 28 Apr
Postcard Cabins St. Francois

Tiny Houses of French Village

2.5 star property
10.0 out of 10, Exceptional, (2)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
The price is SAR 927
SAR 1,373 total
includes taxes & fees
13 Apr - 14 Apr
Tiny Houses of French Village

Drury Inn & Suites St. Louis Arnold

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great staff"
The price is SAR 456
SAR 527 total
includes taxes & fees
20 Apr - 21 Apr
Drury Inn & Suites St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1001)
"Confused entry"
The price is SAR 321
SAR 371 total
includes taxes & fees
20 Apr - 21 Apr
Pear Tree Inn St. Louis Arnold

WoodSpring Suites St. Louis Arnold

2.5 star property
6.0 out of 10, (391)
"Everything "
The price is SAR 285
SAR 330 total
includes taxes & fees
1 May - 2 May
WoodSpring Suites St. Louis Arnold

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
8.0 out of 10, Very Good, (771)
"Great breakfast service Carlos was amazing."
The price is SAR 396
SAR 452 total
includes taxes & fees
28 Apr - 29 Apr
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (797)
"Nice full breakfast. Bed was comfortable."
The price is SAR 335
SAR 392 total
includes taxes & fees
27 Apr - 28 Apr
Comfort Inn Festus - St Louis South

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (629)
"We were in from out of state and everything went perfect!"
The price is SAR 559
SAR 640 total
includes taxes & fees
20 Apr - 21 Apr
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (481)
"Quiet and peaceful. Nice room"
The price is SAR 444
SAR 505 total
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn Farmington

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (405)
"The staff were absolutely the kindest people. Enjoyed the complementary breakfast each morning. The hotel itself was mostly clean but is starting to look a little aged. We had major rain and several leaking areas. Also were super excited to have an indoor pool available but the water was SO COLD even for my rambunctious 5 year old. 😅"
The price is SAR 429
SAR 1,069 total
includes taxes & fees
27 Apr - 28 Apr
Holiday Inn Express & Suites Farmington by IHG

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (528)
"Clean rooms, comfortable beds, and friendly staff!!"
The price is SAR 226
SAR 258 total
includes taxes & fees
13 Apr - 14 Apr
Super 8 by Wyndham Farmington

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (913)
"Clean facility."
The price is SAR 198
SAR 226 total
includes taxes & fees
20 Apr - 21 Apr
Baymont Inn and Suites by Wyndham Farmington, MO

Quality Inn Farmington

2.5 star property
7.8 out of 10, Good, (794)
"Good Hotel"
The price is SAR 191
SAR 229 total
includes taxes & fees
27 Apr - 28 Apr
Quality Inn Farmington

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (521)
"Excellent place to stay. Room was clean and nice. Bathroom was clean. Excellent shower. Great breakfast buffet"
The price is SAR 470
SAR 535 total
includes taxes & fees
11 May - 12 May
Crown Pointe Lodge, BW Signature Collection

Rosener's Inn and banquet center

2.0 star property
5.0 out of 10, (48)
"It's not that bad as it use to be it is ran very professional now and it's more like a business now not a hang out for people "
The price is SAR 203
SAR 226 total
includes taxes & fees
9 May - 10 May
Rosener's Inn and banquet center

Super 8 by Wyndham Bonne Terre

2.0 star property
6.8 out of 10, (456)
"Staff was very friendly "
The price is SAR 191
SAR 209 total
includes taxes & fees
27 Apr - 28 Apr
Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Potosi

2.0 star property
7.0 out of 10, Good, (346)
"There's no bed bugs as some of the "big rich" people said. We checked in here with my kids, they're in the middle of renovations but the room we were in was spacious and comfortable. NO BED BUGS!!! "
The price is SAR 198
SAR 216 total
includes taxes & fees
1 May - 2 May
Super 8 by Wyndham Potosi

YMCA Trout Lodge

2.0 star property
The price is SAR 715
SAR 767 total
includes taxes & fees
11 May - 12 May
YMCA Trout Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

Frequently asked questions

Where is the best place to stay in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG is one of the top choices for your stay based on our traveler data. This aparthotel offers free parking and private balconies. Other good options for your visit to the area are Pear Tree Inn St. Louis Arnold and Baymont Inn and Suites by Wyndham Farmington, MO. See all available top hotels, or vacation rentals in De Soto.

What are some of the best vacation rentals that De Soto has to offer?

Cute Ranch -safe and quiet- 1800 sft living space: This vacation home rental near De Soto offers a balcony, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

Where can I learn more about changing or cancelling my trip to De Soto?

For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.

What are some accommodations with pools in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG: Features 2 outdoor tennis courts, a seasonal outdoor pool, and a sauna. Lakeside Private Villa | 5-Hole Golf On-Site and Pear Tree Inn St. Louis Arnold are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.

What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 7 hotels and other accommodations to choose from. Find out more about De Soto.

What should I do while I'm visiting De Soto?

Natural beauty is on display at Big River, Victoria Glaces Conservation Area Trailhead, and Sunrise Lake Beach. A couple of additional sights to add to your agenda are Washington State Park and Redfield's Flea Market. Check out what more to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.