Find Resorts & Hotels with Spas in Clayton, MO

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check availability on Clayton Resorts & Hotels with Spas

Compare Clayton Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Outdoor dining

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3.0 star property
9.0 out of 10, Wonderful, (820)
"Very comfortable easy chair in room & lots of towels "
The price is SAR 475
SAR 558 total
includes taxes & fees
9 Mar - 10 Mar
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (524)
"Wonderful place to celebrate our 30th wedding anniversary. Everything was exceptional"
The price is SAR 2,059
SAR 2,398 total
includes taxes & fees
21 Mar - 22 Mar
The Ritz-Carlton, St. Louis
Le Méridien St. Louis Clayton
Lounge

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (564)
"Great"
The price is SAR 521
SAR 613 total
includes taxes & fees
6 Mar - 7 Mar
Le Méridien St. Louis Clayton
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
9.0 out of 10, Wonderful, (3001)
"Great location close to WashU. "
The price is SAR 356
SAR 415 total
includes taxes & fees
23 Mar - 24 Mar
Clayton Plaza Hotel & Extended Stay
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property entrance

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (556)
"I had a very pleasant stay at the Seven Gables Inn. The room was big (213) and clean. Huge marble bath and heated toilet. Some of the hotel needs a paint job or renovation but the room was great. People friendly and made an extra effort. My colleague stayed in a different room half the size and was not happy so now I understand the mixed reviews on the site. Ask for room 213 or equivalent. "
The price is SAR 488
SAR 579 total
includes taxes & fees
9 Mar - 10 Mar
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Residence Inn By Marriott St. Louis Clayton
View from property

Residence Inn By Marriott St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (143)
"Hotel staff were amazing , loved the room very spacious definitely was able to relax and would book again "
The price is SAR 619
SAR 765 total
includes taxes & fees
23 Mar - 24 Mar
Residence Inn By Marriott St. Louis Clayton
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Property grounds

King Bed, Comfy Environment, Cozy Space, Corporate Luxury

9.4 out of 10, Exceptional, (3)
"We thoroughly enjoyed our stay. The rooftop views are tremendous!"
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Clayton

Frequently asked questions

Looking for a spa hotel in Clayton?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Clayton. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Clayton?
Among Expedia’s 10 accommodation options in Clayton, there are 3 spa hotels.
What's there to see and do in Clayton?
Enjoy all that Clayton has to offer when you visit Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Zoo, and St. Louis Union Station. If you have some spare time during your trip, you might want to check out Busch Stadium and Gateway Arch.
What is a Clayton spa hotel?
Spa hotels in Clayton provide lodging and have an on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.