Find Resorts & Hotels with Spas in Clayton, MO

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Check availability on Clayton Resorts & Hotels with Spas

Compare Clayton Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Outdoor dining

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3.0 star property
9.0 out of 10, Wonderful, (828)
"It was a great hotel! Will stay there again!"
The price is SAR 475
SAR 558 total
includes taxes & fees
13 Apr - 14 Apr
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (526)
"P"
The price is SAR 2,172
SAR 2,530 total
includes taxes & fees
12 Apr - 13 Apr
The Ritz-Carlton, St. Louis
Le Méridien St. Louis Clayton
Lounge

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (580)
"Nice hotel"
The price is SAR 596
SAR 701 total
includes taxes & fees
12 Apr - 13 Apr
Le Méridien St. Louis Clayton
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
9.0 out of 10, Wonderful, (3353)
"Best sleep I’ve had in a while! Beds are super comfy. It’s quiet and clean. Breakfast was delicious sit-down meal. The night prior we walked to Napoli Italian restaurant, and it was amazing."
The price is SAR 356
SAR 415 total
includes taxes & fees
13 Apr - 14 Apr
Clayton Plaza Hotel & Extended Stay
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property entrance

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (556)
"One of the best hotels/inns I’ve ever stayed in. I travel often for work and have stayed in many hotels. The customer service was top notch! They allowed me to check in early and I got some of the best sleep I’ve had in ages! All the restaurants close by are very good. Highly recommend this place and would easily stay again if I am in the area again! "
The price is SAR 525
SAR 623 total
includes taxes & fees
3 Apr - 4 Apr
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Residence Inn By Marriott St. Louis Clayton
View from property

Residence Inn By Marriott St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (149)
"Very large rooms….Good breakfast…."
The price is SAR 619
SAR 765 total
includes taxes & fees
20 Apr - 21 Apr
Residence Inn By Marriott St. Louis Clayton
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Property grounds

King Bed, Comfy Environment, Cozy Space, Corporate Luxury

9.4 out of 10, Exceptional, (3)
"We thoroughly enjoyed our stay. The rooftop views are tremendous!"
King Bed, Comfy Environment, Cozy Space, Corporate Luxury
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Clayton?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers highly recommend the restaurants in Clayton. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Clayton?
Among Expedia’s 10 accommodation options in Clayton, there are 3 spa hotels.
What's there to see and do in Clayton?
Enjoy all that Clayton has to offer when you visit Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Zoo, and St. Louis Union Station. If you have some spare time during your trip, you might want to check out Busch Stadium and Gateway Arch.
What is a Clayton spa hotel?
Spa hotels in Clayton provide lodging and have an on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.