Find Luxury Hotels in Clayton, MO

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Compare Clayton Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Ritz-Carlton, St. Louis
Exterior

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (522)
"We like everything. This was our first trip to St Louis. The hotel and surroundings exceeded all our expectations. We booked 3 rooms and they got us all on the same floor. It was Christmas and the decorations and festivities were wonderful."
The price is SAR 2,024
SAR 2,358 total
includes taxes & fees
11 Jan - 12 January 2025
The Ritz-Carlton, St. Louis
Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
9.0 out of 10, Wonderful, (2924)
"Clean courteous staff n pleasant"
The price is SAR 375
SAR 436 total
includes taxes & fees
26 Jan - 27 January 2025
Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton
Room

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (546)
"Clean, very friendly staff. Very nice rooms! "
The price is SAR 597
SAR 701 total
includes taxes & fees
28 Dec - 29 Dec
Le Méridien St. Louis Clayton
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Exterior

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (552)
"The staff was terrific. "
The price is SAR 507
SAR 602 total
includes taxes & fees
1 Jan - 2 January 2025
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you looking for a luxury hotel for your stay in Clayton?
While you’re visiting, you might want to think about enjoying the museums and sporting events, which Clayton is known for.
What's the best luxury place to stay in Clayton?
The Ritz-Carlton, St. Louis is a luxury hotel with spa services and valet parking, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
What's the best time to vacation in Clayton?
The hottest months are usually July and August with an average temperature of 76°F,
  • Coldest months: January, February, December, and March
  • Driest months: January, February, December, and November
  • Rainiest months: April, May, June, and August
What's there to see and do in Clayton?
Experience Clayton with a stop at Chapel of St. Timothy And St. Titus, Concordia Seminary, St. Louis Union Station, and Saint Louis Galleria Mall. If you have extra time while you’re in the area, you might want to see The Loop and St. Louis Art Museum.
How can I get around Clayton?
It’s easier to get around town comfortably when you know your options. Head to Clayton Station for metro transit.