Find 5 Star Hotels in Panama City from SAR 307
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Panama City 5 Star Hotels
Tonight
Tomorrow
Next weekend
In two weeks
Compare Panama City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
9.0 out of 10, Wonderful, (3665)
The price is SAR 452
SAR 497 total
includes taxes & fees
27 Feb - 28 Feb

Waldorf Astoria Panama
Waldorf Astoria Panama
9.0 out of 10, Wonderful, (1002)
The price is SAR 1,019
SAR 1,121 total
includes taxes & fees
1 Mar - 2 Mar

W Panama
W Panama
8.8 out of 10, Excellent, (1002)
The price is SAR 773
SAR 850 total
includes taxes & fees
5 Mar - 6 Mar

Hilton Panama
Hilton Panama
8.8 out of 10, Excellent, (1003)
The price is SAR 807
SAR 888 total
includes taxes & fees
1 Mar - 2 Mar

JW Marriott Panama
JW Marriott Panama
8.8 out of 10, Excellent, (1003)
The price is SAR 1,196
SAR 1,316 total
includes taxes & fees
1 Mar - 2 Mar

The Westin Playa Bonita Panama
The Westin Playa Bonita Panama
8.0 out of 10, Very Good, (1002)
The price is SAR 673
SAR 741 total
includes taxes & fees
4 Mar - 5 Mar

Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (395)
The price is SAR 1,266
SAR 1,392 total
includes taxes & fees
28 Feb - 1 Mar

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (549)
The price is SAR 859
SAR 945 total
includes taxes & fees
28 Feb - 1 Mar
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.

Crowne Plaza Panama Airport, an IHG Hotel
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is SAR 488 per night from Feb 23 to Feb 24
SAR 488
SAR 536 total
includes taxes & fees
23 Feb - 24 Feb
8.2/10 Very Good! (2,073 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Panama City hotels
Recent reviews of Panama City hotels

Hilton Panama
5/5 Excellent
"The hotel was very nice, clean and luxurious.
There were Christmas celebrations going on at ground level and we heard nothing from our room.
Beautiful hotel. "
A verified traveler from Sherwood Park stayed at Hilton Panama
Posted 21 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Panama City Hotels by Star Rating
Stay near popular Panama City attractions
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Cinta Costera
- Hotels near Amador Causeway
- Hotels near Avenida Balboa
- Hotels near Via Espana
- Hotels near Fuerte Amador Resort & Marina
- Hotels near El Dorado Mall
- Hotels near Miraflores Locks
- Hotels near Panama Viejo
- Hotels near Uruguay Street
- Hotels near Los Pueblos Commercial Center
- Hotels near Iglesia del Carmen
- Hotels near ATLAPA Conventions Center
- Hotels near Soberania National Park
- Hotels near Calle 50
- Hotels near Crown Casino
- Hotels near Amador Convention Center
- Hotels near Metropolitan Cathedral of Panama
- Hotels near Panama Canal Railway
More Hotel Options in Panama City
- Adults Only Resorts & Hotels in Panama City
- Adventure Hotels in Panama City
- All-inclusive Hotel in Panama City
- Beach Hotels in Panama City
- Boutique Hotels in Panama City
- Business Hotels in Panama City
- Casinos in Panama City
- Cheap Hotels in Panama City
- Family Hotels in Panama City
- Golf Hotels in Panama City
- Green Hotels in Panama City
- Historic Hotels in Panama City
- Hotel Wedding Venues in Panama City
- Hotel with a Concierge in Panama City
- Hotels with Bars in Panama City
- Hotels with Early Check-in in Panama City
- Hotels with Free Parking in Panama City
- Hotels with Hot Tubs in Panama City
- Hotels with WiFi in Panama City
- Hotels with a Pool in Panama City
- Hotels with an Indoor Pool in Panama City
- Hotels with smoking rooms in Panama City
- Luxury Hotels in Panama City
- Pet-friendly Hotels in Panama City
- Resorts & Hotels with Spas in Panama City
- Romantic Hotels in Panama City
- Shopping Hotels in Panama City
- Ski Hotels in Panama City
- Waterpark Hotels in Panama City
- Winery Hotels in Panama City
Explore more hotels
- Waymore Hotel Spa & Casino
- The Executive Hotel
- Hilton Panama
- Ramada Plaza By Wyndham Panama Punta Pacífica
- Las Americas Golden Tower Panama
- TRYP by Wyndham Panamá Centro
- Hospedium Princess Hotel Panama
- Principe Hotel and Suites
- Megapolis Hotel Panamá
- MARINN PLACE Financial District
- Sofitel Legend Casco Viejo, Panama City
- Sheraton Grand Panama
- Hotel Costa Inn
- Holiday Inn Panama Distrito Financiero, an IHG Hotel
- Bristol Panama, a Registry Collection Hotel
- Residence Inn by Marriott Panama City
- Studio Coliving
- American Trade Hotel
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Riande Urban Hotel
Expedia's Latest Trends
Flights
Flights to RenfrewshireFlights to ChedgraveFlights to KentonFlights to BodinnickFlights to AjmanFlights to SalcombeFlights to IvegillFlights to DockingFlights to PeakirkFlights to Wemyss BayFlights to New LuceFlights to DearhamFlights to KincraigieFlights to SemleyFlights to UttoxeterFlights to CavendishFlights to Cotford St LukeFlights to TorbayFlights to CalthwaiteFlights to BoxgroveFlights to Four MarksFlights to MiddlewichFlights to Aberdovey