Photo by RVLuckyorWhat
Find 4 Star Hotels in Santee, CA from SARĀ 371
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Santee 4 Star Hotels
Tonight
Tomorrow
Next weekend
In two weeks
Compare Santee 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

San Diego Marriott La Jolla
San Diego Marriott La Jolla
8.4 out of 10, Very Good, (1656)
The price is SARĀ 537
SARĀ 606 total
includes taxes & fees
20 Apr - 21 Apr

Sheraton Mission Valley San Diego Hotel
Sheraton Mission Valley San Diego Hotel
8.4 out of 10, Very Good, (1366)
The price is SARĀ 443
SARĀ 499 total
includes taxes & fees
24 Mar - 25 Mar

San Diego Mission Bay Resort
San Diego Mission Bay Resort
8.2 out of 10, Very Good, (1146)
The price is SARĀ 634
SARĀ 884 total
includes taxes & fees
21 Apr - 22 Apr

Omni San Diego Hotel
Omni San Diego Hotel
9.0 out of 10, Wonderful, (1906)
The price is SARĀ 747
SARĀ 1,007 total
includes taxes & fees
18 Apr - 19 Apr

Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
8.8 out of 10, Excellent, (2628)
The price is SARĀ 657
SARĀ 909 total
includes taxes & fees
20 Apr - 21 Apr

Wyndham San Diego Bayside
Wyndham San Diego Bayside
8.2 out of 10, Very Good, (5634)
The price is SARĀ 571
SARĀ 643 total
includes taxes & fees
31 Mar - 1 Apr

Sheraton San Diego Resort
Sheraton San Diego Resort
8.0 out of 10, Very Good, (2578)
The price is SARĀ 570
SARĀ 795 total
includes taxes & fees
20 Apr - 21 Apr

Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
9.2 out of 10, Wonderful, (1627)
The price is SARĀ 761
SARĀ 991 total
includes taxes & fees
29 Mar - 30 Mar
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santee.

Pendry San Diego
550 J Street, San Diego, CA
The price is SARĀ 1,032 per night from Apr 10 to Apr 11
SARĀ 1,032
SARĀ 1,354 total
includes taxes & fees
10 Apr - 11 Apr
9.2/10 Wonderful! (982 reviews)
Still don't see what you're looking for?
See all properties in Santee.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Santee
Come to relaxing Santee and enjoy its golf, food, and zoo.

Recent reviews of Santee hotels
Recent reviews of Santee hotels

Wyndham San Diego Bayside
5/5 Excellent
"If you are taking a cruise this is the hotel for you. Any closer and you would be on the Pier! Friendly, efficient employees. Very satisfied with the room and the amenities. Will definitely return!"
A verified traveler stayed at Wyndham San Diego Bayside
Posted 9 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Santee Hotels by Star Rating
Hotels in Santee Neighborhoods
Stay near popular Santee attractions
- Hotels near Sportsplex USA Santee
- Hotels near Santee Lakes
- Hotels near Mission Trails Regional Park
- Hotels near Carlton Oaks Country Club
- Hotels near Lakeside Baseball Park
- Hotels near San Diego Christian College
- Hotels near Santee Boulders
- Hotels near Old Mission Dam
- Hotels near Creation and Earth History Museum
- Hotels near Off Broadway Live
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Diego Zoo Safari Park
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Petco Park
- Hotels near Mission Beach
- Hotels near San Diego State University
- Hotels near Hotel Circle
More Hotel Options in Santee
- Adventure Hotels in Santee
- Beach Hotels in Santee
- Business Hotels in Santee
- Cheap Hotels in Santee
- Family Hotels in Santee
- Golf Hotels in Santee
- Hotel Wedding Venues in Santee
- Hotels with Bars in Santee
- Hotels with Free Parking in Santee
- Hotels with Hot Tubs in Santee
- Hotels with WiFi in Santee
- Hotels with a Pool in Santee
- Hotels with smoking rooms in Santee
- Luxury Hotels in Santee
- Pet-friendly Hotels in Santee
- Resorts & Hotels with Spas in Santee
- Shopping Hotels in Santee
More Accommodation Types in Santee
- Vacation Homes in Santee
- Apartments in Santee
- Condo Rentals in Santee
- Cottages in Santee
- Villas in Santee
- Guest Houses in Santee
- Resorts in Santee
- Motels in Santee
- Aparthotels in Santee
- Hostels in Santee
- Farmstay in Santee
- Cabin Rentals in Santee
- B&B in Santee
- RV Parks in Santee
- Inns in Santee
- Houseboats in Santee
- Ranches in Santee
Explore more hotels
- Best Western Seven Seas
- Omni San Diego Hotel
- Handlery Hotel
- The Little Italy Hotel Downtown San Diego
- Paradise Point Resort & Spa
- Kings Inn San Diego
- Bay Club Hotel & Marina
- Hard Rock Hotel San Diego
- Lafayette Hotel & Club
- Hilton San Diego Mission Valley
- Best Western Premier Hotel Del Mar
- Loews Coronado Bay Resort
- Hyatt Regency Mission Bay Spa and Marina
- La Jolla Cove Suites
- Marriott Marquis San Diego Marina
- Embassy Suites by Hilton San Diego La Jolla
- Palihotel San Diego Gaslamp Quarter
- DoubleTree by Hilton San Diego - Del Mar
- Alma San Diego Downtown, a Tribute Portfolio Hotel
- Manchester Grand Hyatt San Diego