Find hotels in Vandalia, MO from SAR 203
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Compare 60 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Comfort Inn & Suites - Hannibal
Comfort Inn & Suites - Hannibal
7.6 out of 10, Good, (552)
The price is SAR 334
SAR 395 total
includes taxes & fees
29 Mar - 30 Mar

Baymont by Wyndham Hannibal
Baymont by Wyndham Hannibal
6.2 out of 10, (617)
The price is SAR 236
SAR 272 total
includes taxes & fees
16 Mar - 17 Mar

Days Inn by Wyndham Hannibal
Days Inn by Wyndham Hannibal
7.2 out of 10, Good, (138)
The price is SAR 225
SAR 259 total
includes taxes & fees
13 Apr - 14 Apr

Howard Johnson BY Wyndham Hannibal
Howard Johnson BY Wyndham Hannibal
7.0 out of 10, Good, (106)
The price is SAR 203
SAR 233 total
includes taxes & fees
16 Mar - 17 Mar

Knights Inn New Florence
Knights Inn New Florence
6.8 out of 10, (476)
The price is SAR 255
SAR 289 total
includes taxes & fees
22 Mar - 23 Mar

The Junction Inn
The Junction Inn
6.0 out of 10, (17)
The price is SAR 320
SAR 339 total
includes taxes & fees
21 Mar - 22 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Vandalia
Check out Bill Trower Memorial Park and Perry Park—just a couple of the sights around Vandalia.
More cheap stays in Vandalia
More cheap stays in Vandalia

Comfort Inn & Suites - Hannibal
4000 Market St, Hannibal, MO
The price is SAR 334 per night from Mar 29 to Mar 30
SAR 334
SAR 395 total
includes taxes & fees
29 Mar - 30 Mar
7.4/10 Good! (552 reviews)
Hotels in Vandalia with star-rating
Hotels in Vandalia with star-rating

3 Star Hotels
3 properties

2 Star Hotels
14 properties
Recent reviews of Vandalia hotels
Recent reviews of Vandalia hotels

Comfort Inn & Suites - Hannibal
5/5 Excellent
"Clean and quiet. Beds were fairly comfy. Breakfast was decent - about what you expect. This hotel met our needs and was a fair price."
A verified traveler stayed at Comfort Inn & Suites - Hannibal
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Stay near popular Vandalia attractions
- Hotels near Mississippi River
- Hotels near Mark Twain Cave
- Hotels near Mark Twain State Park
- Hotels near Mark Twain Birthplace State Historic Site
- Hotels near Graham Cave State Park
- Hotels near Hillside Mini Golf
- Hotels near Lakeview Park
- Hotels near New Florence United Methodist Church
- Hotels near Audrain County Historical Society
- Hotels near American Saddle Horse Museum
- Hotels near Sodalis Nature Preserve
- Hotels near Presser Performing Arts Center
Other Hotels near Vandalia, Missouri
- Hannibal Hotels
- Ozarks Hotels
- Mexico Hotels
- Central United States Hotels
- Auxvasse Hotels
- Perry Hotels
- Bowling Green Hotels
- Louisiana Hotels
- Monroe City Hotels
- New Florence Hotels
- Palmyra Hotels
- Stoutsville Hotels
- High Hill Hotels
- New London Hotels
- Montgomery City Hotels
- Clarksville Hotels
- Hawk Point Hotels
- Williamsburg Hotels
- Silex Hotels
- Eolia Hotels
Explore more hotels
- Budget Inn
- Holder House at Beautiful Mark Twain Lake.
- 3 Bedroom 2 Bath Cabin nestled in the woods minutes from Mark Twain Lake.
- “Peaceful Retreat” @ MTL
- Kennedys Red Barn Inn
- Charming 2-bedroom house at Mark Twain Lake
- Mark Twain lake getaway at Blue Lagoon!
- Fishing & Boating 3 Bed/2 Bath Cozy Cabin at Mark Twain Lake!
- Garth Woodside Mansion B&B
- Family Condo By Mark Twain Lake & Jellystone Park
- Brady Hotel
- A real charmer built in 1915 , pet friendly , located next to Mark Twain lake.