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Compare 1,315 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (3424)
"The only thing that I didn’t like was that you don’t provide enough water, only 2 bottles of water in a hot city is kind of cheap."
The price is SAR 432
SAR 475 total
includes taxes & fees
23 Dec - 24 Dec
Hotel Riu Plaza Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1005)
"Soooo amazing! Loved this hotel it’s like mini Dubai if you’ve ever been to aura sky pool! Beautiful and amazing stay! "
The price is SAR 785
SAR 864 total
includes taxes & fees
10 Jan - 11 January 2025
JW Marriott Panama

Plaza Paitilla Inn Hotel

3.5 star property
9.2 out of 10, Wonderful, (1719)
"C"
The price is SAR 336
SAR 370 total
includes taxes & fees
5 Jan - 6 January 2025
Plaza Paitilla Inn Hotel

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1007)
"Muy agradable el hotel y tremenda localización "
The price is SAR 307
SAR 338 total
includes taxes & fees
4 Jan - 5 January 2025
Decapolis Hotel Panama City

W Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"The property and room was amazing!!! The staff were very friendly and helpful. "
The price is SAR 605
SAR 666 total
includes taxes & fees
10 Jan - 11 January 2025
W Panama

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1004)
"Beautiful hotel in nice location. Room was spacious and comfortable. TV didn’t work. No ice is a problem. Minibar is ridiculous and takes up entire fridge space. Lobby Restaurant menu has only a few items. Breakfast Buffet is excellent."
The price is SAR 635
SAR 699 total
includes taxes & fees
3 Jan - 4 January 2025
Waldorf Astoria Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"Shouldn’t charge for parking if you’re a guest plus hilton member. Wrong. For the rest everything is fine "
The price is SAR 635
SAR 699 total
includes taxes & fees
10 Jan - 11 January 2025
Hilton Panama

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (716)
"Very nice! This is one of the best hotels in Panama !"
The price is SAR 538
SAR 591 total
includes taxes & fees
25 Dec - 26 Dec
Megapolis Hotel Panamá

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1008)
"Hotel was amazing only that there was no pool but property is nice and located in the shopping areas "
The price is SAR 331
SAR 364 total
includes taxes & fees
5 Jan - 6 January 2025
Novotel Panama City

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.4 out of 10, Exceptional, (1006)
"Very good customer service and good location "
The price is SAR 350
SAR 385 total
includes taxes & fees
23 Dec - 24 Dec
Ramada Plaza By Wyndham Panama Punta Pacífica

Waymore Hotel Spa & Casino

4.0 star property
9.0 out of 10, Wonderful, (128)
"Jorge at the front desk was excellent. He was so helpful. King's cafe staff was very nice too. I wish they had a standard timing for SPA we wanted to get a message on Sunday they said the staff took off that day which was disappointing"
The price is SAR 355
SAR 432 total
includes taxes & fees
23 Dec - 24 Dec
Waymore Hotel Spa & Casino

Principe Hotel and Suites

3.0 star property
8.8 out of 10, Excellent, (1168)
"Great central place! "
The price is SAR 269
SAR 295 total
includes taxes & fees
31 Dec - 1 January 2025
Principe Hotel and Suites

Hospedium Princess Hotel Panama

3.5 star property
7.8 out of 10, Good, (369)
"very good"
The price is SAR 208
SAR 229 total
includes taxes & fees
5 Jan - 6 January 2025
Hospedium Princess Hotel Panama

Riande Urban Hotel

3.5 star property
8.6 out of 10, Excellent, (1008)
"It was a wonderful place but the only thing we didn’t have any refrigerator in our room but everything was excellent "
The price is SAR 298
SAR 327 total
includes taxes & fees
23 Dec - 24 Dec
Riande Urban Hotel

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (359)
"El hotel es hermoso. Tiene muchos detalles. El diseño y la arquitectura. La ubicación. Es como en las fotos. La gente muy servicial. Puedes pedir cualquier comida de la carta las 24 horas del día y te lo llevan a la habitación. Nuestra habitación tenía un balcón bello en donde nos colocaron una mesa rodante de donde venía la comida que ordenamos. Muy especial. La cama y almohadas muy cómodas. Estilo colonial hermoso! "
The price is SAR 1,319
SAR 1,450 total
includes taxes & fees
8 Jan - 9 January 2025
Sofitel Legend Casco Viejo, Panama City

Summit Rainforest & Golf Resort

4.0 star property
8.4 out of 10, Very Good, (1007)
"We had a great experience at the hotel that was clean. The balcony offered an excellent view to the nature. The personnel was available to assist. Will repeat the experience for sure."
The price is SAR 302
SAR 340 total
includes taxes & fees
30 Dec - 31 Dec
Summit Rainforest & Golf Resort

Holiday Inn Panama Distrito Financiero, an IHG Hotel

4.0 star property
8.8 out of 10, Excellent, (1006)
"Great location and friendly staff "
The price is SAR 323
SAR 355 total
includes taxes & fees
3 Jan - 4 January 2025
Holiday Inn Panama Distrito Financiero, an IHG Hotel

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1004)
"Beautiful facility "
The price is SAR 641
SAR 705 total
includes taxes & fees
13 Jan - 14 January 2025
Las Americas Golden Tower Panama

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1010)
"We only stayed 1 night as a stopover but was just what we needed. Clean room, comfortable bed and big bathroom. Buffet breakfast was good but staff kept asking if they could help - it's a buffet so I don't need help. "
The price is SAR 537
SAR 591 total
includes taxes & fees
3 Jan - 4 January 2025
Marriott Panama Hotel

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (778)
"Central Hotel Panamá is perfectly located in Casco Viejo surrounded by the beauty of the local architecture. Lots of great nearby locations to eat including restaurants on site. The hotel is warm and inviting with a spa aroma that greets you as you travel throughout. I would highly recommend a stay here."
The price is SAR 911
SAR 1,002 total
includes taxes & fees
23 Dec - 24 Dec
Central Hotel Panama Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Santa Clara?

Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Decapolis Hotel Panama City and Dreams Playa Bonita Panama - All Inclusive. See all available top hotels, or vacation rentals in Santa Clara.

What's the top vacation rental in Santa Clara?

Oasis with pool near panama canal: This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa Clara.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.

Where can I learn more about changing or cancelling my trip to Santa Clara?

To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.

What's the best place to stay near Culebra Cut?

Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.

What is staying in Santa Clara like?

Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1315 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.

What is there to see in Santa Clara?

A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.

What's the seasonal weather like in Santa Clara?

The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.