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Compare 743 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Country Inn & Suites by Radisson, Roanoke, VA
Country Inn & Suites by Radisson, Roanoke, VA

La Quinta Inn & Suites by Wyndham Roanoke Salem
La Quinta Inn & Suites by Wyndham Roanoke Salem

Hyatt Place Roanoke Airport/Valley View Mall
Hyatt Place Roanoke Airport/Valley View Mall

Comfort Inn Roanoke Civic Center
Comfort Inn Roanoke Civic Center

Avid Hotels Salem by IHG
Avid Hotels Salem by IHG

Hampton Inn & Suites Roanoke Airport
Hampton Inn & Suites Roanoke Airport
Great weekend hotel deals in Roanoke, VA
Image gallery for Fire Station One Boutique Hotel

Fire Station One Boutique Hotel
Go beyond your typical stay in Roanoke
Roanoke and related destinations
The Star City of the South, named after one of its most popular attractions, is surrounded by scenic mountains and offers great museums, theaters and art galleries.

Visit ancient Indian burial grounds, admire a wealth of fine historical architecture and dance in lively music venues when you come to Macon.

Visit the final resting place of the Wright brothers at this Midwestern destination, which offers historical attractions in a modern city setting.

Famous for its booming art scene, historic downtown and close proximity to New York City, this town is an ideal East Coast destination.

Visit clean, green Somerset County to discover historic settlements, important Revolutionary War sites, fine golf courses and upscale restaurants.

Stay near popular Roanoke attractions
Stay near popular Roanoke attractions

Center in the Square
Find out about the history of Roanoke when you spend time at Center in the Square. Discover the area's mountain views and shops.
Recent reviews of Roanoke hotels
Recent reviews of Roanoke hotels

The Liberty Trust
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Roanoke Neighborhoods
Stay near popular Roanoke attractions
- Hotels near Berglund Center
- Hotels near Carilion Roanoke Memorial Hospital
- Hotels near Tanglewood Mall
- Hotels near Valley View Mall
- Hotels near Center in the Square
- Hotels near Hollins University
- Hotels near Mill Mountain Star
- Hotels near Virginia Museum of Transportation
- Hotels near Taubman Museum of Art
- Hotels near Jefferson Center
- Hotels near Civic Center
- Hotels near Mill Mountain Zoo
- Hotels near Mill Mountain Park
- Hotels near St. Andrews Catholic Church
- Hotels near Carvins Cove
- Hotels near Roanoke Pinball Museum
- Hotels near Virginia's Explore Park
- Hotels near Science Museum of Western Virginia
- Hotels near Splash Valley at Green Ridge Recreation Center
- Hotels near Roanoke Visitor Center
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