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Compare 600 Vacation Homes in Picayune with updated reviews, rates, and availability.

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
9.6 out of 10, Exceptional, (238)

Location! 1/2 Block to Beach and 4 Blocks to MAIN STREET! Great Quiet Location!
Location! 1/2 Block to Beach and 4 Blocks to MAIN STREET! Great Quiet Location!
10.0 out of 10, Exceptional, (57)

Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!
Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!
10.0 out of 10, Exceptional, (137)

Peggy Sue
Peggy Sue
10.0 out of 10, Exceptional, (40)

Sunset bay view 1
Sunset bay view 1
9.8 out of 10, Exceptional, (100)

Tranquil coastal retreat with private pool, fireplace, & sunlit yard
Tranquil coastal retreat with private pool, fireplace, & sunlit yard
9.4 out of 10, Exceptional, (10)

Seaside Serenity: Find peace at the beach & relax by our beautiful pool oasis!
Seaside Serenity: Find peace at the beach & relax by our beautiful pool oasis!
10.0 out of 10, Exceptional, (10)

Main Street Pool and Hot Tub Oasis BSL 039
Main Street Pool and Hot Tub Oasis BSL 039
10.0 out of 10, Exceptional, (41)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Picayune

Incredible Lakefront home
Incredible Lakefront home
9.6 out of 10, Exceptional, (31)
The price is SAR 563
SAR 1,505 total
includes taxes & fees
17 Apr - 18 Apr

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
9.6 out of 10, Exceptional, (238)

Cozy room .4 mile walk to beautiful seawall over looking the Bay of Saint Louis.
Cozy room .4 mile walk to beautiful seawall over looking the Bay of Saint Louis.
9.2 out of 10, Wonderful, (24)
The price is SAR 244
SAR 443 total
includes taxes & fees
19 Apr - 20 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Picayune hotels
Recent reviews of Picayune hotels

Microtel Inn & Suites by Wyndham Pearl River/Slidell
5/5 Excellent
"This is a good place to stay if you are traveling on I-10. It is clean and safe. The staff is friendly and helpful. "
A verified traveler from WILLISTON stayed at Microtel Inn & Suites by Wyndham Pearl River/Slidell
Posted 2 days ago