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Compare 600 Vacation Homes in Picayune with updated reviews, rates, and availability.

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
9.6 out of 10, Exceptional, (232)

Location! 1/2 Block to Beach and 4 Blocks to MAIN STREET! Great Quiet Location!
Location! 1/2 Block to Beach and 4 Blocks to MAIN STREET! Great Quiet Location!
10.0 out of 10, Exceptional, (52)

Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!
Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!
10.0 out of 10, Exceptional, (136)

Peggy Sue
Peggy Sue
10.0 out of 10, Exceptional, (36)

Sunset bay view 1
Sunset bay view 1
9.8 out of 10, Exceptional, (98)

Tranquil coastal retreat with private pool, fireplace, & sunlit yard
Tranquil coastal retreat with private pool, fireplace, & sunlit yard
9.4 out of 10, Exceptional, (10)

Seaside Serenity: Find peace at the beach & relax by our beautiful pool oasis!
Seaside Serenity: Find peace at the beach & relax by our beautiful pool oasis!
10.0 out of 10, Exceptional, (10)

Main Street Pool and Hot Tub Oasis BSL 039
Main Street Pool and Hot Tub Oasis BSL 039
10.0 out of 10, Exceptional, (39)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Picayune

Location! 1/2 Block to Beach and 4 Blocks to MAIN STREET! Great Quiet Location!
Location! 1/2 Block to Beach and 4 Blocks to MAIN STREET! Great Quiet Location!
10.0 out of 10, Exceptional, (52)

Incredible Lakefront home
Incredible Lakefront home
9.4 out of 10, Exceptional, (30)
The price is SAR 563
SAR 1,504 total
includes taxes & fees
6 Apr - 7 Apr

“Prime Location” New Beachfront 3 Bedroom on the BEACH in downtown Bay St Louis
“Prime Location” New Beachfront 3 Bedroom on the BEACH in downtown Bay St Louis
10.0 out of 10, Exceptional, (106)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Picayune hotels
Recent reviews of Picayune hotels

Holiday Inn Express Picayune-Stennis Space Center by IHG
5/5 Excellent
"It was nice and clean with room option for the temp that you choose. The breakfast is delicious with lots of options. "
A verified traveler from Columbia stayed at Holiday Inn Express Picayune-Stennis Space Center by IHG
Posted 1 day ago