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Compare 23 Vacation Homes in Pamplico with updated reviews, rates, and availability.

Cheerful home with plenty of privacy and entertainment room.
Master Bedroom

Cheerful home with plenty of privacy and entertainment room.

8.4 out of 10, Very Good, (19)
"Spacious home, with plenty of room for 6 adults. Just a heads-up, there's a sweet cat on the property. We found out a couple of days before, and let the owner know we had someone with a severe allergy. They made sure she wasn't able to come in the house, and we didn't have any trouble with reactions inside. The kitchen could use an update, but we there are plenty of dishes, utensils and spices available. Located on the edge of town, but still near plenty of food and grocery options. Having the...
Cheerful home with plenty of privacy and entertainment room.
Waterfront Paradise with Golf Course Views
Property grounds

Waterfront Paradise with Golf Course Views

6.2 out of 10, (11)
"The house offers plenty of space (the bedrooms are massive) - think early 70’s ranch layout - with an amazing view of the lake (plenty of deer, a blue heron, geese and ducks). Our host went out of their way to make sure that we were able to cook a full Thanksgiving feast! If you’re looking for a quiet home to rest and relax, you’ve found it. "
Waterfront Paradise with Golf Course Views
Hickory Haven 3Br Elegant Downtown Hidden Gem
Bathroom

Hickory Haven 3Br Elegant Downtown Hidden Gem

9.4 out of 10, Exceptional, (13)
"Hickory Haven was absolutely beautiful home, clean smelled fresh and you walk in amazed, it doesn’t look that big from the outside but it was perfect huge inside! Yes my initial thought was “oh my” the neighborhood however no issues it was quite and the neighbors were nice! These craft homes are getting make overs but one house at a time, that it why you can’t judge a book by the cover! No one bothered us I do wish the road was wider but that didn’t make us unhappy, the home was cute and...
Hickory Haven 3Br Elegant Downtown Hidden Gem
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Living area

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

8.6 out of 10, Excellent, (4)
"Very clean, comfortable, welcoming. The only thing is all the bedrooms are upstairs. We didn’t realize that. We are older & have knee problems, but we managed. The neighborhood is very nice& the neighbors are friendly. Miko was very accommodating. "
The price is SAR 751
SAR 2,235 total
includes taxes & fees
27 Jan - 28 January 2025
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Peaceful Farm Getaway
Room

Peaceful Farm Getaway

9.8 out of 10, Exceptional, (16)
"Nice quiet place to stay for a few weeks while I commuted locally for work. Definitely recommend! "
The price is SAR 507
SAR 786 total
includes taxes & fees
27 Jan - 28 January 2025
Peaceful Farm Getaway
Pineapple House: Historic. Southern Charm. Walk Downtown.
Welcome to the Pineapple House!

Pineapple House: Historic. Southern Charm. Walk Downtown.

9.4 out of 10, Exceptional, (13)
"The property was very clean and had nice decor. Bed was very comfortable and liked that there was a lot of towels for us to use. Communication with the host was excellent. They responded right away to our questions prior to check in. Check in was a breeze. The kitchen had everything we needed. The note from the host was a nice surprise. Location was convenient in that it was close to restaurants and the hospital. Neighborhood was quiet."
Pineapple House: Historic. Southern Charm. Walk Downtown.
Quaint Bungalow in Historic Downtown Florence
Living area

Quaint Bungalow in Historic Downtown Florence

10.0 out of 10, Exceptional, (11)
"The pictures on the VRBO app does not do this charming home justice, upon arrival the pink door alone was inviting but after opening the door, the oooh’s and the ahhhh’s started! You walk in and you are grinning from ear to ear the decor of this crafted 1930’s home was so beautiful, the hosts went into to great detail remodeling and updating the home but keeping it simple with clean lines and colors the decorator needs to teach me this skill! I did take pictures of everything I liked! The beds...
Quaint Bungalow in Historic Downtown Florence
Walking distance from one of South Carolina's top Medical centers.
Family room.

Walking distance from one of South Carolina's top Medical centers.

9.8 out of 10, Exceptional, (32)
"We stayed at this great home when we came to Florence for a race. It was roomy and comfortable and perfect for the four of us. I love the big open kitchen! It was convenient to the places we needed to be and we felt safe and secure in the neighborhood. The host was excellent in messaging and making sure we had everything we needed, and the home was very well stocked. We’ve decided this will be where we stay every time we come down for a race now. Highly recommend! "
The price is SAR 312
SAR 643 total
includes taxes & fees
5 Jan - 6 January 2025
Walking distance from one of South Carolina's top Medical centers.
Great Home in the Greater Florence Area
Exterior

Great Home in the Greater Florence Area

9.6 out of 10, Exceptional, (5)
"Nice location and home. Owner was very responsive and accommodating. Matt promptly addressed our initial concerns after checkin. I would consider this home again for potential future bookings. "
Great Home in the Greater Florence Area
Townhouse in Florence SC closed to MUSC medical center.
Living area

Townhouse in Florence SC closed to MUSC medical center.

Townhouse in Florence SC closed to MUSC medical center.
Comfy Townhome~ Modern Farmhouse with Full Office!
Bathroom

Comfy Townhome~ Modern Farmhouse with Full Office!

10.0 out of 10, Exceptional, (2)
"I had a very nice stay in Florence at this property. I was working from home through the week and the office setup was perfect."
Comfy Townhome~ Modern Farmhouse with Full Office!
2B/1.5 Bath Brand new Townhouse Closed to MUSC
Living area

2B/1.5 Bath Brand new Townhouse Closed to MUSC

2.0 star property
10.0 out of 10, Exceptional, (1)
"Great property, very clean and everything you need is provided. "
2B/1.5 Bath Brand new Townhouse Closed to MUSC
Jacqueline Estates
Mathematical Suite - soaking tub. Jacqueline (the owners mother) loved math.

Jacqueline Estates

10.0 out of 10, Exceptional, (6)
"My family enjoyed our stay. The house has a great flow for hosting my sons graduation celebration. Great details added throughout the house to make it cozy and inviting. The fire pit in the back yard was nice for making s’mores. Plenty of parking for our guest. The host is quick to respond to questions and made us feel at home. "
Jacqueline Estates
Cozy Mullins Retreat w/ Backyard & Covered Porch!
Mullins Vacation Rental | 2BR | 1BA | 1,200 Sq Ft | Steps Required

Cozy Mullins Retreat w/ Backyard & Covered Porch!

2.0 star property
10.0 out of 10, Exceptional, (1)
"Neat older home with everything cleaned up and new appliances. "
Cozy Mullins Retreat w/ Backyard & Covered Porch!
Charming 3-bedroom house in Florence, SC
Room

Charming 3-bedroom house in Florence, SC

Charming 3-bedroom house in Florence, SC
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Exterior

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

10.0 out of 10, Exceptional, (11)
"10/10 highly recommend if your in the area and need a place to stay. Very comfy, cozy and at home feel. "
The price is SAR 668
SAR 1,127 total
includes taxes & fees
27 Jan - 28 January 2025
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Luxury stay at 4 bedroom house
Exterior

Luxury stay at 4 bedroom house

9.0 out of 10, Wonderful, (2)
"We went to Florence for a family reunion and wanted a place close by. The house is fine but slightly strange in its decor. It's perfectly fine, safe, and the host responds to questions very quickly,"
Luxury stay at 4 bedroom house
Travel Nurses Only - Cozy, Comfortable and Clean Home
Room

Travel Nurses Only - Cozy, Comfortable and Clean Home

Travel Nurses Only - Cozy, Comfortable and Clean Home
Charming 3-bedroom home in Florence near McLeod Hospital.
Room

Charming 3-bedroom home in Florence near McLeod Hospital.

10.0 out of 10, Exceptional, (2)
Charming 3-bedroom home in Florence near McLeod Hospital.
Work Friendly House Downtown Florence
Interior

Work Friendly House Downtown Florence

Work Friendly House Downtown Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Pamplico

Cozy log cabin with plenty of space in Florence, SC
Exterior

Cozy log cabin with plenty of space in Florence, SC

9.6 out of 10, Exceptional, (40)
"We really enjoyed our stay at this cabin. It was so cozy, beautifully decorated, and had all of the amenities that we needed. The owners were very responsive and great to work with. Highly recommend! "
Cozy log cabin with plenty of space in Florence, SC
Secret SC Cabin on 100 acres Hot Tub Large Pond
Hideaway Haven

Secret SC Cabin on 100 acres Hot Tub Large Pond

9.6 out of 10, Exceptional, (163)
"We had a fantastic stay for a wedding at Hidden Acres. Perfect location. Cozy cabin with great views."
The price is SAR 845
SAR 1,862 total
includes taxes & fees
27 Jan - 28 January 2025
Secret SC Cabin on 100 acres Hot Tub Large Pond
Cheerful home with plenty of privacy and entertainment room.
Master Bedroom

Cheerful home with plenty of privacy and entertainment room.

8.4 out of 10, Very Good, (19)
"Spacious home, with plenty of room for 6 adults. Just a heads-up, there's a sweet cat on the property. We found out a couple of days before, and let the owner know we had someone with a severe allergy. They made sure she wasn't able to come in the house, and we didn't have any trouble with reactions inside. The kitchen could use an update, but we there are plenty of dishes, utensils and spices available. Located on the edge of town, but still near plenty of food and grocery options. Having the...
Cheerful home with plenty of privacy and entertainment room.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.