Photo by Corey Dargan

Find Luxury Hotels in Orangeburg, SC

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Orangeburg Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Travelodge by Wyndham Orangeburg
Exterior

Travelodge by Wyndham Orangeburg

2.0 star property
8.2 out of 10, Very Good, (857)
"This place was very clean. The guy who checked us in was so sweet. Will stay again when traveling through "
The price is SAR 252
SAR 280 total
includes taxes & fees
6 Jan - 7 January 2025
Travelodge by Wyndham Orangeburg
Red Roof Inn Santee
Room

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (586)
"Good!"
The price is SAR 252
SAR 279 total
includes taxes & fees
1 Jan - 2 January 2025
Red Roof Inn Santee
Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (929)
"Clean safe property "
The price is SAR 372
SAR 413 total
includes taxes & fees
30 Jan - 31 January 2025
Comfort Inn & Suites Santee
Baymont by Wyndham Orangeburg North
Exterior

Baymont by Wyndham Orangeburg North

2.5 star property
6.4 out of 10, (1001)
"Room had spiderwebs connecting the floor to the furniture. Ceiling was peeling toilet was hard to flush & the top on it was the wrong size . We have stayed there many times but haven’t been in two years . Not as nice as it was ."
The price is SAR 252
SAR 279 total
includes taxes & fees
12 Jan - 13 January 2025
Baymont by Wyndham Orangeburg North
Baymont by Wyndham Santee
Exterior

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1272)
"The staff were very nice and very helpful! The girls at the front desk we're great and did a wonderful job!! They deserve recognition for their politeness and customer service skills!! Keep up the great work!! And I will be back to stay with you again! Happy new year!!!"
The price is SAR 300
SAR 333 total
includes taxes & fees
9 Jan - 10 January 2025
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Room

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (506)
"The people were weird outside and the ice bucket didn’t come with a plastic bag in it. Everything else was good. Clean room, friendly man at the desk. "
The price is SAR 338
SAR 375 total
includes taxes & fees
6 Jan - 7 January 2025
Ramada by Wyndham Santee I-95
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (304)
"Check in was easy."
The price is SAR 241
SAR 267 total
includes taxes & fees
20 Jan - 21 January 2025
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Orangeburg

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Orangeburg?
Use Expedia and let us help you arrange a flight to Columbia Metropolitan Airport (CAE) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Orangeburg offers. During your visit, you might want to enjoy the sporting events and university which Orangeburg is known for.
How many luxury hotels can I expect to find in Orangeburg?
Lie in the lap of luxury during your getaway to Orangeburg in one of Expedia’s 14 luxury hotels.
When can I expect good weather in Orangeburg?
Planning for the weather is a good way to make your trip to Orangeburg relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Orangeburg is 52 inches.
What's there to see and do in Orangeburg?
Experience Orangeburg with a stop at Smith-Hammond-Middleton Memorial Center, South Carolina State College Historic District, and Edisto Memorial Gardens. If you have a little extra time during your trip, you might want to make a stop at Claflin University and South Carolina State University.