Photo by Corey Dargan
Find Luxury Hotels in Orangeburg, SC
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Orangeburg Luxury Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare Orangeburg Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Travelodge by Wyndham Orangeburg
Travelodge by Wyndham Orangeburg
8.2 out of 10, Very Good, (906)
The price is SAR 334
SAR 371 total
includes taxes & fees
7 Mar - 8 Mar

Red Roof Inn Santee
Red Roof Inn Santee
6.6 out of 10, (595)
The price is SAR 251
SAR 279 total
includes taxes & fees
9 Mar - 10 Mar

Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
8.0 out of 10, Very Good, (952)
The price is SAR 379
SAR 421 total
includes taxes & fees
12 Mar - 13 Mar

Baymont by Wyndham Orangeburg North
Baymont by Wyndham Orangeburg North
6.4 out of 10, (1003)
The price is SAR 319
SAR 354 total
includes taxes & fees
9 Mar - 10 Mar

Baymont by Wyndham Santee
Baymont by Wyndham Santee
8.0 out of 10, Very Good, (1291)
The price is SAR 300
SAR 333 total
includes taxes & fees
12 Mar - 13 Mar

Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95
6.2 out of 10, (514)
The price is SAR 252
SAR 279 total
includes taxes & fees
12 Mar - 13 Mar

Econo Lodge
Econo Lodge
6.4 out of 10, (307)
The price is SAR 304
SAR 338 total
includes taxes & fees
20 Mar - 21 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Orangeburg
Find out more about Orangeburg
Recent reviews of Orangeburg hotels
Recent reviews of Orangeburg hotels

Travelodge by Wyndham Orangeburg
5/5 Excellent
"Very clean, friendly and easy checkin."
A verified traveler stayed at Travelodge by Wyndham Orangeburg
Posted 4 days ago

Baymont by Wyndham Orangeburg North
5/5 Excellent
"Just what we needed. Have stayed here multiple times on our way to Florida. Thanks"
A verified traveler stayed at Baymont by Wyndham Orangeburg North
Posted 3 weeks ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Orangeburg
More Hotel Options in Orangeburg
- Adults Only Resorts & Hotels in Orangeburg
- Adventure Hotels in Orangeburg
- Beach Hotels in Orangeburg
- Business Hotels in Orangeburg
- Cheap Hotels in Orangeburg
- Family Hotels in Orangeburg
- Golf Hotels in Orangeburg
- Historic Hotels in Orangeburg
- Hotel with a Concierge in Orangeburg
- Hotels with Bars in Orangeburg
- Hotels with Free Parking in Orangeburg
- Hotels with Hot Tubs in Orangeburg
- Hotels with WiFi in Orangeburg
- Hotels with a Pool in Orangeburg
- Hotels with an Indoor Pool in Orangeburg
- Hotels with smoking rooms in Orangeburg
- Pet-friendly Hotels in Orangeburg
- Resorts & Hotels with Spas in Orangeburg
- Romantic Hotels in Orangeburg
- Shopping Hotels in Orangeburg
More Accommodation Types in Orangeburg
- Condo Rentals in South Carolina
- Vacation Homes in South Carolina
- Apartments in South Carolina
- Villas in South Carolina
- Resorts in South Carolina
- Cottages in South Carolina
- Cabin Rentals in South Carolina
- Motels in South Carolina
- Aparthotels in South Carolina
- B&B in South Carolina
- Guest Houses in South Carolina
- Lodges in South Carolina
- Condo Resorts in South Carolina
- Houseboats in South Carolina
- Inns in South Carolina
- Country Houses in South Carolina
- Hostels in South Carolina
Hotels near popular Orangeburg Attractions
- Hotels near Edisto Memorial Gardens
- Hotels near Lake Marion
- Hotels near Congaree National Park
- Hotels near Santee State Park
- Hotels near South Carolina State University
- Hotels near Santee Cooper Country Club
- Hotels near Santee Outlets
- Hotels near Santee National Wildlife Refuge
- Hotels near Santee National Golf Club
- Hotels near God's Acre Healing Springs
Orangeburg Hotels by Star Rating
Explore more hotels
- Sleep Inn Orangeburg
- Orangeburg Inn & Suites
- Comfort Inn & Suites
- Secluded Cabin Retreat with Hot Tub, for Family Get Away Pond dam busted
- Nene’s Cozy Corner
- Suburban Studios
- Days Inn by Wyndham Orangeburg South
- RayneBow Royalty
- Quaint Orangeburg Townhome Near Hospitals & Campus
- Centally located w/ coffee bar, theatre/gameroom
- Baymont by Wyndham Santee
- Days Inn by Wyndham St George
- Tru By Hilton Santee
- Fairfield Inn & Suites by Marriott Santee
- Holiday Inn Santee, an IHG Hotel
- Hampton Inn Santee-I-95
- Best Western Plus Santee Inn
- Comfort Inn & Suites Santee
- Travelodge by Wyndham Santee
- Budget Inn By Belvilla St George I-95