Photo by Corey Dargan

Find Luxury Hotels in Orangeburg, SC

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Check availability on Orangeburg Luxury Hotels

Compare Orangeburg Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Travelodge by Wyndham Orangeburg
Exterior

Travelodge by Wyndham Orangeburg

2.0 star property
8.2 out of 10, Very Good, (918)
"Very nice"
The price is SAR 300
SAR 334 total
includes taxes & fees
29 Mar - 30 Mar
Travelodge by Wyndham Orangeburg
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (598)
"Typical Red Roof Inn. We liked the parking at front door style of this motel and that was close to restaurants. The breakfast selection was not great, even for a continental. "
The price is SAR 263
SAR 291 total
includes taxes & fees
30 Mar - 31 Mar
Red Roof Inn Santee
Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very Good, (960)
"Parking spaces were to small, had to crawl through car to get out 😞."
The price is SAR 411
SAR 457 total
includes taxes & fees
13 Apr - 14 Apr
Comfort Inn & Suites Santee
Baymont by Wyndham Orangeburg North
Seasonal outdoor pool

Baymont by Wyndham Orangeburg North

2.5 star property
6.4 out of 10, (1060)
"It's the least expensive for a reason. The beds and furniture is new and comfortable. However, the room walls and bathrooms are very much in need serious Re-do. "
The price is SAR 244
SAR 271 total
includes taxes & fees
1 Apr - 2 Apr
Baymont by Wyndham Orangeburg North
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very Good, (1385)
"A clean, comfortable hotel. Only downside was the minimalist breakfast bar with no scrambled eggs and bacon/sausage. Our third stay here and we will probably stay here again. Keith, Toronto March 2025"
The price is SAR 300
SAR 333 total
includes taxes & fees
30 Mar - 31 Mar
Baymont by Wyndham Santee
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (517)
"Everyone that works here is very nice, including the owner. I feel safe and comfortable."
Ramada by Wyndham Santee I-95
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (307)
"Check in was easy."
Econo Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Orangeburg?
Use Expedia and let us help you arrange a flight to Columbia Metropolitan Airport (CAE) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Orangeburg offers. During your visit, you might want to enjoy the sporting events and university which Orangeburg is known for.
How many luxury hotels can I expect to find in Orangeburg?
Lie in the lap of luxury during your getaway to Orangeburg in one of Expedia’s 14 luxury hotels.
When can I expect good weather in Orangeburg?
Planning for the weather is a good way to make your trip to Orangeburg relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Orangeburg is 52 inches.
What's there to see and do in Orangeburg?
Experience Orangeburg with a stop at Edisto Memorial Gardens, South Carolina State College Historic District, and Smith-Hammond-Middleton Memorial Center. If you have a little extra time during your trip, you might want to make a stop at Claflin University and South Carolina State University.