Find Resorts & Hotels with Spas in O'Fallon, MO

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Pick from 7 O'Fallon Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
8.8 out of 10, Excellent, (1010)
"My wife and I have stayed at the hotel several times. The facility is always clean, breakfast is always great, and the staff is always friendly and kind. I highly recommend this property."
The price is SAR 297
SAR 343 total
includes taxes & fees
9 Dec - 10 Dec
Sleep Inn & Suites O'Fallon MO - Technology Drive

Comfort Inn & Suites St. Louis - O'Fallon

2.5 star property
7.6 out of 10, Good, (936)
"Room was great. A little pealing paint above the bathtub. Quiet. Would definitely stay here again. "
The price is SAR 355
SAR 409 total
includes taxes & fees
26 Nov - 27 Nov
Comfort Inn & Suites St. Louis - O'Fallon

Super 8 by Wyndham O'Fallon MO/St. Louis Area

2.0 star property
6.8 out of 10, (903)
"Great overall, staff was great, rooms were clean"
The price is SAR 255
SAR 293 total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Residence Inn by Marriott O'Fallon

3.0 star property
8.4 out of 10, Very Good, (400)
"Very good "
The price is SAR 428
SAR 496 total
includes taxes & fees
15 Dec - 16 Dec
Residence Inn by Marriott O'Fallon

Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel

2.5 star property
8.4 out of 10, Very Good, (634)
"Loved the room we’ll definitely stay again. Just it needs to policy to clean the rooms daily unless guest asked for the rooms not to be clean. Staying in a hotel for two days you accumulate a lot of trash because of eating out. Also, there were a lot of wet towels from showering. Also, it needs to be made aware to pay attention to how many people are checking into the room because putting four towels and no washcloths in a room for a family of five we had to keep going downstairs to get...
The price is SAR 386
SAR 443 total
includes taxes & fees
27 Nov - 28 Nov
Holiday Inn Express St. Louis West - O'Fallon, an IHG Hotel

Hilton Garden Inn St. Louis/O'Fallon MO

3.0 star property
8.8 out of 10, Excellent, (652)
"We had a great time and loved this hotel."
The price is SAR 380
SAR 434 total
includes taxes & fees
1 Dec - 2 Dec
Hilton Garden Inn St. Louis/O'Fallon MO

Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic

9.8 out of 10, Exceptional, (31)
"This home is very spacious and well appointed. Super comfortable and very relaxing. Would stay here again without question. Plenty of shopping and dining options nearby."
The price is SAR 860
SAR 1,727 total
includes taxes & fees
26 Nov - 27 Nov
Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic

Updated & Cozy 3 BDR Home

8.8 out of 10, Excellent, (6)
"The property was listed as ‘smoke free’ but we smelled cigarette smoke when we walked in. The property was clean and the beds were comfortable. It was a quiet neighborhood."
Updated & Cozy 3 BDR Home

Golf Heaven and Nature Lovers

10.0 out of 10, Exceptional, (29)
"This is our "go to" when we visit family in Lake St. Louis. Comfortable, clean and close to all our activities - it is a winner. See you next time...."
Golf Heaven and Nature Lovers

The Secret Sojourn | JZ Vacation Rentals

10.0 out of 10, Exceptional, (1)
"The property was very nice , with a big yard. The house was super clean when we showed up and the host was super quick to respond to any questions or concerns. Overall I would recommend staying here!"
The Secret Sojourn | JZ Vacation Rentals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in O'Fallon?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Check out the lakeside setting in O’Fallon - worth a picture or two! Enjoy the shopping and many popular restaurants during your vacation. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your holiday.
How many spa hotels will I find in O'Fallon?
Among Expedia’s 19 accommodation options in O’Fallon, there is 1 spa hotel.
What's there to see and do in O'Fallon?
Take in some sights and attractions while you’re in O’Fallon by visiting CarShield Field, 9-11 Memorial, and Mississippi River. If you have some spare time during your trip, you might want to check out Alligator Creek Aquatic Center and Mid Rivers Mall.
What is a O'Fallon spa hotel?
Spa hotels in O’Fallon provide lodging and have a full on-site spa which offers services such as therapies and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.