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Find hotels in O Brien, FL from SAR 225
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Compare 317 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75
9.4 out of 10, Exceptional, (401)
The price is SAR 437
SAR 491 total
includes taxes & fees
11 May - 12 May

Americas Best Value Inn Alachua
Americas Best Value Inn Alachua
4.8 out of 10, (548)
The price is SAR 243
SAR 273 total
includes taxes & fees
6 May - 7 May

Royal Inn
Royal Inn
7.2 out of 10, Good, (175)
The price is SAR 503
SAR 566 total
includes taxes & fees
18 May - 19 May

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
9.2 out of 10, Wonderful, (1004)
The price is SAR 469
SAR 527 total
includes taxes & fees
11 May - 12 May

Vista Verde Farm Retreat
Vista Verde Farm Retreat
10.0 out of 10, Exceptional, (4)
The price is SAR 486
SAR 711 total
includes taxes & fees
7 May - 8 May

BlueGem Motel
BlueGem Motel
9.2 out of 10, Wonderful, (348)
The price is SAR 347
SAR 390 total
includes taxes & fees
12 May - 13 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien
Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

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More cheap stays in O Brien
More cheap stays in O Brien

La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE, Lake City, FL
The price is SAR 368 per night from May 6 to May 7
SAR 368
SAR 414 total
includes taxes & fees
6 May - 7 May
8.8/10 Excellent! (1,015 reviews)
Hotels in O Brien with star-rating
Hotels in O Brien with star-rating

3 Star Hotels
19 properties
Recent reviews of O Brien hotels
Recent reviews of O Brien hotels

Comfort Suites Lake City
5/5 Excellent
"good"
A verified traveler stayed at Comfort Suites Lake City
Posted 2 days ago
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Stay near popular O Brien attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River State Park
- Hotels near Ichetucknee River
- Hotels near Southside Sports Complex
- Hotels near Santa Fe River
- Hotels near Lake City Mall
- Hotels near Southside Recreation Complex
- Hotels near Poe Springs Park
- Hotels near O'Leno State Park
- Hotels near North Florida Speedway
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Wes Skiles Peacock Springs State Park
- Hotels near Columbia County Courthouse
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Big Shoals State Park
- Hotels near Stephen Foster Folk Culture Center
- Hotels near Stephen Foster State Folk Center
- Hotels near Epiphany Catholic Church
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