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Find hotels in O Brien, FL from SAR 230
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Compare 320 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Suwannee River Rendezvous
Suwannee River Rendezvous
8.2 out of 10, Very Good, (12)
The price is SAR 338
SAR 453 total
includes taxes & fees
8 Jun - 9 Jun

Cindys Motel
Cindys Motel
8.8 out of 10, Excellent, (107)

Americas Best Value Inn Lake City
Americas Best Value Inn Lake City
8.8 out of 10, Excellent, (999)
The price is SAR 244
SAR 274 total
includes taxes & fees
11 May - 12 May

Gateway Inn
Gateway Inn
7.6 out of 10, Good, (65)
The price is SAR 230
SAR 259 total
includes taxes & fees
12 May - 13 May

Comfort Suites Lake City
Comfort Suites Lake City
9.6 out of 10, Exceptional, (1000)
The price is SAR 403
SAR 454 total
includes taxes & fees
12 May - 13 May

Guest Inn
Guest Inn
6.0 out of 10, (182)
The price is SAR 257
SAR 289 total
includes taxes & fees
15 May - 16 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien
Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

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More cheap stays in O Brien
More cheap stays in O Brien

La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE, Lake City, FL
The price is SAR 368 per night from May 11 to May 12
SAR 368
SAR 414 total
includes taxes & fees
11 May - 12 May
8.6/10 Excellent! (1,023 reviews)
Hotels in O Brien with star-rating
Hotels in O Brien with star-rating

3 Star Hotels
19 properties
Recent reviews of O Brien hotels
Recent reviews of O Brien hotels

La Quinta Inn & Suite by Wyndham Lake City
5/5 Excellent
"This one of our routine stays"
A verified traveler from Vero Beach stayed at La Quinta Inn & Suite by Wyndham Lake City
Posted 22 hours ago
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Stay near popular O Brien attractions
- Hotels near Ichetucknee Springs State Park
- Hotels near Ginnie Spring
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Hotels near Suwannee River State Park
- Hotels near Ichetucknee River
- Hotels near Southside Sports Complex
- Hotels near Santa Fe River
- Hotels near Lake City Mall
- Hotels near Southside Recreation Complex
- Hotels near Poe Springs Park
- Hotels near O'Leno State Park
- Hotels near North Florida Speedway
- Hotels near Lake City Veterans Affairs Medical Center
- Hotels near Wes Skiles Peacock Springs State Park
- Hotels near Columbia County Courthouse
- Hotels near Lake City Columbia County Historical Museum
- Hotels near Big Shoals State Park
- Hotels near Stephen Foster Folk Culture Center
- Hotels near Stephen Foster State Folk Center
- Hotels near Epiphany Catholic Church
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