Photo by Dr__Vlad

Find hotels in O Brien, FL from SAR 225

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Compare 314 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hampton Inn & Suites Alachua I-75

2.5 star property
9.4 out of 10, Exceptional, (386)
"Very clean hotel "
The price is SAR 443
SAR 499 total
includes taxes & fees
13 Apr - 14 Apr
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

2.0 star property
4.8 out of 10, (533)
"Property needs full renovation"
The price is SAR 316
SAR 355 total
includes taxes & fees
18 Mar - 19 Mar
Americas Best Value Inn Alachua

Royal Inn

2.0 star property
7.2 out of 10, Good, (169)
"It's a very old hotel but economically priced and the front desk employee, maybe owner, was very friendly and quick. The bathroom definitely needs updating or a better clean. We chose not to shower due to looking like mold. It may have been a stain as the rest of the room was clean. "
The price is SAR 293
SAR 329 total
includes taxes & fees
18 Mar - 19 Mar
Royal Inn

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
9.2 out of 10, Wonderful, (1002)
"A nice clean and comfortable hotel. Good breakfast and pleasant staff. "
The price is SAR 497
SAR 559 total
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Vista Verde Farm Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The price is SAR 472
SAR 695 total
includes taxes & fees
25 Mar - 26 Mar
Vista Verde Farm Retreat

BlueGem Motel

2.0 star property
9.2 out of 10, Wonderful, (338)
"Nice and very clean "
The price is SAR 375
SAR 422 total
includes taxes & fees
24 Mar - 25 Mar
BlueGem Motel

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (524)
"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."
The price is SAR 251
SAR 282 total
includes taxes & fees
18 Mar - 19 Mar
Palms Garden Inn

The Blanche

2.0 star property
9.2 out of 10, Wonderful, (117)
"Beautifully kept! We loved everything about it. Would definitely stay here again. "
The price is SAR 656
SAR 738 total
includes taxes & fees
18 Mar - 19 Mar
The Blanche

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1002)
"Clean, well priced, close to interstate "
The price is SAR 271
SAR 305 total
includes taxes & fees
19 Mar - 20 Mar
Days Inn by Wyndham Lake City I-10

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (7)
"Nice clean"
The price is SAR 422
SAR 464 total
includes taxes & fees
8 Apr - 9 Apr
Postcard Cabins Gilchrist Springs

Super 8 by Wyndham Lake City

2.0 star property
7.0 out of 10, Good, (596)
"Nice stay and light the free supper, and eggs in the morning, the Wister with some meat selection. People were friendly but my only complaint would be the thin walls between the guest rooms. I could hear my neighbor and his TV playing 24/7 over 3 days"
The price is SAR 331
SAR 372 total
includes taxes & fees
23 Mar - 24 Mar
Super 8 by Wyndham Lake City

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (727)
"This was a bare bones hotel. The room was clean and the beds were comfortable. There was Wi-Fi and a tv, and not much else. If all you want is a comfortable bed, then this is the place for you. "
The price is SAR 270
SAR 304 total
includes taxes & fees
24 Mar - 25 Mar
Driftwood Inn

Regal Inn

2.5 star property
8.6 out of 10, Excellent, (474)
"I really liked this room. Really like the colors and the beds and the barn door to the bathroom. The gentleman at the front desk was very friendly and helpful. The air conditioner and the shower worked perfectly. We got a great night's sleep. And the price was perfect."
The price is SAR 246
SAR 277 total
includes taxes & fees
31 Mar - 1 Apr
Regal Inn

Courtyard By Marriott Lake City

3.0 star property
9.8 out of 10, Exceptional, (34)
"One of the nicest hotels I've stayed in in a long time"
The price is SAR 401
SAR 451 total
includes taxes & fees
30 Mar - 31 Mar
Courtyard By Marriott Lake City

Days Inn by Wyndham Lake City I-75

2.0 star property
7.4 out of 10, Good, (1006)
"Comfortable, clean bed"
The price is SAR 258
SAR 291 total
includes taxes & fees
23 Mar - 24 Mar
Days Inn by Wyndham Lake City I-75

Knights Inn Lake City

1.5 star property
5.4 out of 10, (601)
"Nice 👍🙂"
The price is SAR 225
SAR 253 total
includes taxes & fees
18 Mar - 19 Mar
Knights Inn Lake City

Holiday Inn & Suites Lake City by IHG

3.0 star property
8.4 out of 10, Very Good, (1000)
"The hotel was so fresh and clean. The beds were amazing. Right across the street from Cracker barrell and I 75 super close. Love it"
The price is SAR 379
SAR 426 total
includes taxes & fees
23 Mar - 24 Mar
Holiday Inn & Suites Lake City by IHG

Quality Inn Lake City

2.5 star property
7.8 out of 10, Good, (842)
"Very friendly staff, safe & clean environment. Pillows were hard & lumpy :( but everything else was great!"
The price is SAR 314
SAR 353 total
includes taxes & fees
13 Apr - 14 Apr
Quality Inn Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
8.8 out of 10, Excellent, (1005)
"Great breakfast bar! "
The price is SAR 413
SAR 464 total
includes taxes & fees
30 Mar - 31 Mar
La Quinta Inn & Suite by Wyndham Lake City

Rodeway Inn Lake City I-75

2.0 star property
6.6 out of 10, (368)
"quite "
The price is SAR 253
SAR 285 total
includes taxes & fees
25 Mar - 26 Mar
Rodeway Inn Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Frequently asked questions

Where is the best place to stay in O Brien?

La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Courtyard By Marriott Lake City and Americas Best Value Inn Lake City. See all available top hotels, or vacation rentals in O Brien.

What's the top vacation rental in O Brien?

Pet-Friendly Florida Escape w/ Patio & Fire Pit!: Visitors give good reviews to this O Brien vacation home rental, which offers a patio, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other homes for rent in O Brien include Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY. See all vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

Where can I learn more about changing or cancelling my trip to O Brien?

To access more information about picking new dates or cancelling your trip to O Brien, click here.

Where is the best hotel to stay near Ichetucknee Springs State Park?

Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.

What are some accommodations with pools in O Brien?

La Quinta Inn & Suite by Wyndham Lake City: Features on-the-go, an indoor pool, and free self parking. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and Courtyard By Marriott Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.

What's the best hotel for staying near Gainesville Regional Airport (GNV)?

Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.

How is it to stay in O Brien?

Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.

What should I see while I'm in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lake City Mall in the area. Check out what more to see and do in Expedia's O Brien guide.

What's the seasonal weather like in O Brien?

The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.