Find Resorts & Hotels with Spas in Greenville, SC

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Greenville Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Embassy Suites Greenville Golf Resort & Conference Center
Exterior

Embassy Suites Greenville Golf Resort & Conference Center

3.5 star property
8.8 out of 10, Excellent, (1001)
"The hotel is beautiful. It has everything you need for an overnight or extended stay. It was super clean and the staff were amazing. It was very busy but it was pin drop quiet in your room. The breakfast buffet was incredible and they were serving up some great drinks at the bar. Highly recommend staying here!!"
The price is SAR 415
SAR 470 total
includes taxes & fees
12 Jan - 13 January 2025
Embassy Suites Greenville Golf Resort & Conference Center
Hotel Hartness
Exterior

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (422)
"Very nice quiet hotel. Super clean. Fine dining restaurant superb. "
The price is SAR 636
SAR 826 total
includes taxes & fees
19 Jan - 20 January 2025
Hotel Hartness
Embassy Suites by Hilton Greenville Downtown Riverplace
Exterior

Embassy Suites by Hilton Greenville Downtown Riverplace

3.5 star property
9.2 out of 10, Wonderful, (1000)
"Co great location staff were very friendly. I would stay there again"
The price is SAR 568
SAR 643 total
includes taxes & fees
19 Jan - 20 January 2025
Embassy Suites by Hilton Greenville Downtown Riverplace
Drury Inn & Suites Greenville
Exterior

Drury Inn & Suites Greenville

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Very friendly and accommodating, I enjoy my stay every time I go there."
The price is SAR 406
SAR 446 total
includes taxes & fees
5 Jan - 6 January 2025
Drury Inn & Suites Greenville
Hyatt Place Greenville/Downtown
Exterior

Hyatt Place Greenville/Downtown

3.0 star property
9.2 out of 10, Wonderful, (1005)
"I would highly recommend this property! Nice looking facility! "
The price is SAR 462
SAR 523 total
includes taxes & fees
3 Jan - 4 January 2025
Hyatt Place Greenville/Downtown
The Westin Poinsett Greenville
Exterior

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1002)
"Cannot say enough good things about this place ! "
The price is SAR 635
SAR 719 total
includes taxes & fees
5 Jan - 6 January 2025
The Westin Poinsett Greenville
Hampton Inn Greenville I-385 - Woodruff Rd.
Room

Hampton Inn Greenville I-385 - Woodruff Rd.

3.0 star property
8.8 out of 10, Excellent, (736)
"Quiet and staff at front desk were great"
The price is SAR 396
SAR 448 total
includes taxes & fees
12 Jan - 13 January 2025
Hampton Inn Greenville I-385 - Woodruff Rd.
Residence Inn by Marriott Greenville Downtown
Reception

Residence Inn by Marriott Greenville Downtown

3.0 star property
9.4 out of 10, Exceptional, (293)
"My king room was awesome! Huge comfy and had everything we needed. "
The price is SAR 554
SAR 622 total
includes taxes & fees
26 Jan - 27 January 2025
Residence Inn by Marriott Greenville Downtown
La Quinta Inn & Suites by Wyndham Greenville Haywood
Exterior

La Quinta Inn & Suites by Wyndham Greenville Haywood

2.5 star property
7.6 out of 10, Good, (1000)
"I visit my sister 2 to 3 times a year. I use this hotel every time. It is consistent. A decent place for a great price. The breakfast is certainly a bonus with the bacon, sausage and eggs. Nice job on that."
The price is SAR 331
SAR 364 total
includes taxes & fees
5 Jan - 6 January 2025
La Quinta Inn & Suites by Wyndham Greenville Haywood
Best Western Plus Greenville I-385 Inn & Suites
Exterior

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1291)
"The hotel was fine.Just a little noisy from the side road"
The price is SAR 318
SAR 350 total
includes taxes & fees
12 Jan - 13 January 2025
Best Western Plus Greenville I-385 Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Greenville

Frequently asked questions

Looking to vacation at a spa hotel in Greenville?
Treat yourself to some pampering and book a hotel with a spa. Travelers highly recommend Greenville for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the live music and waterfalls during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Greenville?
Hotel Hartness is a top spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, body scrub, or body wrap at the onsite spa. Another popular spa hotel in Greenville is Grand Bohemian Lodge Greenville, Autograph Collection.
How many spa hotels will I find in Greenville?
Among Expedia’s 602 accommodation options in Greenville, there are 2 spa hotels.
What's there to see and do in Greenville?
Take in the sights and attractions that Greenville offers with a visit to The Peace Center, The Children’s Museum of the Upstate, and Falls Park on the Reedy. If you have some spare time during your trip, you might want to check out Bon Secours Wellness Arena and Greenville Zoo.
What is a Greenville spa hotel?
Spa hotels in Greenville have full on-site spas and offer services like couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.