Find hotels in East Main Street, Grand Junction from SAR 174
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Discover 565 East Main Street hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

The Homestead
The Homestead
10.0 out of 10, Exceptional, (30)
The price is SAR 570
SAR 600 total
includes taxes & fees
6 Mar - 7 Mar

Spoke and Vine Motel
Spoke and Vine Motel
9.8 out of 10, Exceptional, (143)
The price is SAR 709
SAR 783 total
includes taxes & fees
6 Mar - 7 Mar

Wine Country Inn Palisade
Wine Country Inn Palisade
9.6 out of 10, Exceptional, (1003)
The price is SAR 596
SAR 662 total
includes taxes & fees
6 Mar - 7 Mar

Best Western Grande River Inn & Suites
Best Western Grande River Inn & Suites
9.0 out of 10, Wonderful, (662)
The price is SAR 316
SAR 332 total
includes taxes & fees
9 Mar - 10 Mar

Motel 6 Grand Junction, CO
Motel 6 Grand Junction, CO
6.2 out of 10, (1000)
The price is SAR 195
SAR 224 total
includes taxes & fees
6 Mar - 7 Mar

Residence Inn by Marriott Grand Junction
Residence Inn by Marriott Grand Junction
8.8 out of 10, Excellent, (436)
The price is SAR 428
SAR 490 total
includes taxes & fees
7 Mar - 8 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Main Street
Where to stay in East Main Street
Hotels in top Grand Junction neighborhoods Learn more about East Main Street

Downtown
1 out of top 10 points of interest in this area
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.
Recent reviews of East Main Street hotels
Recent reviews of East Main Street hotels

La Quinta Inn & Suites by Wyndham Grand Junction
5/5 Excellent
"No complaints"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Grand Junction
Posted 1 day ago
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Hotels near popular Grand Junction Attractions
- Hotels near Colorado Mesa University
- Hotels near Colorado River
- Hotels near Colorado National Monument
- Hotels near Canyon View Park
- Hotels near Two Rivers Convention Center
- Hotels near Redlands Mesa Golf Club
- Hotels near Bananas Fun Park
- Hotels near Mesa County Fairgrounds
- Hotels near Gunnison River
- Hotels near Western Colorado Botanical Gardens
More Accommodation Types in East Main Street
Hotels Close to Nearby Airports
East Main Street Hotels by Star Rating
Explore more hotels
- Holiday Inn and Suites Grand Junction, an IHG Hotel
- Comfort Inn & Suites
- La Quinta Inn & Suites by Wyndham Fruita
- SpringHill Suites by Marriott Grand Junction Downtown/Historic Main St.
- Tru by Hilton Grand Junction Downtown
- Camp Eddy
- Home2 Suites by Hilton Grand Junction Northwest
- Holiday Inn Express & Suites Grand Junction, an IHG Hotel
- Studio 6 Grand Junction, CO
- Super 8 by Wyndham Fruita
- Quality Inn Grand Junction near University
- Days Inn by Wyndham Grand Junction