Find All Southwest Illinois Hotels
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Find All Southwest Illinois Hotels
We have found 651 Southwest Illinois Hotels
- Walker's Bluff Casino Resort
- Drury Plaza Hotel Mt. Vernon
- Drury Inn & Suites St. Louis O'Fallon, IL
- Super 8 by Wyndham O'Fallon
- Drury Inn & Suites Marion
- DoubleTree by Hilton Mt. Vernon
- Baymont by Wyndham Marion
- Drury Inn & Suites St. Louis Fairview Heights
- Red Lion Inn & Suites Pontoon Beach
- Drury Inn & Suites St. Louis Collinsville
- Super 8 by Wyndham Marion
- Comfort Suites Mount Vernon
- Holiday Inn Express & Suites Mount Vernon, an IHG Hotel
- Best Western Plus Pontoon Beach
- Comfort Suites Fairview Heights
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Super 8 by Wyndham Troy IL/St. Louis Area
- Quality Inn & Suites near St. Louis and I-255
- Best Western Marion Hotel
- Super 8 by Wyndham Mt. Vernon IL
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- Town & Country Inn
- Comfort Inn & Suites Marion I-57
- Holiday Inn Express Troy, an IHG Hotel
- Holiday Inn Express & Suites Edwardsville, an IHG Hotel
- Super 8 by Wyndham Carbondale
- Country Inn & Suites by Radisson, Marion, IL
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Days Inn by Wyndham Collinsville/St. Louis
- Baymont by Wyndham O'Fallon St. Louis Area
- Super 8 by Wyndham Fairview Heights-St. Louis
- Seasons Inn & Suites Highland
- Quality Inn & Suites Caseyville - St. Louis
- Best Western Plus MidAmerica Hotel
- Holiday Inn Express & Suites Murphysboro - Carbondale, an IHG Hotel
- Home2 Suites by Hilton Carbondale
- Fairfield Inn & Suites by Marriott O'Fallon, IL
- Red Lion Inn & Suites Caseyville
- SureStay Hotel by Best Western Whittington Rend Lake
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- Quality Inn And Suites
- Hampton Inn & Suites St. Louis-Edwardsville
- Comfort Inn Collinsville near St. Louis
- Days Inn by Wyndham Mount Vernon
- Holiday Inn Express & Suites - O'Fallon /Shiloh, an IHG Hotel
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Holiday Inn St. Louis Fairview Heights, an IHG Hotel
- Best Western Troy Hotel
- Best Western Saluki Inn
- Quality Inn O'Fallon IL - St. Louis
- Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
- Hotel 7 Inn Anna
- TownePlace Suites by Marriott St. Louis Edwardsville, IL
- Holiday Inn Express Hotel & Suites Marion Northeast, an IHG Hotel
- Quality Inn Mount Vernon, IL
- Western Hotels
- Holiday Inn Express & Suites Vandalia, an IHG Hotel
- Comfort Inn Edwardsville - St. Louis
- Fairfield Inn by Marriott St. Louis Collinsville, IL
- Hampton Inn O'Fallon
- Hampton Inn Collinsville
- Hampton Inn St. Louis - Columbia
- Baymont by Wyndham Chester IL
- Candlewood Suites O Fallon, an IHG Hotel
- Motel 6 Mount Vernon, IL
- Fairgrounds Inn
- Holiday Inn Express & Suites Salem, an IHG Hotel
- Super 8 by Wyndham Belleville St. Louis Area
- Royal Relax Inn
- Days Inn by Wyndham Pontoon Beach
- Holiday Inn Carbondale-Conference Center, an IHG Hotel
- Quality Inn Carbondale University area
- Sleep Inn O'Fallon near I-64
- Rodeway Inn & Suites
- Days Inn by Wyndham Salem, Illinois
- Econo Lodge
- Country Hearth Inn & Suites Edwardsville St. Louis
- Super 8 by Wyndham Collinsville St. Louis
- Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
- Radisson Hotel Fairview Heights - St. Louis
- Red Roof Inn St Louis - Troy, IL
- Quality Inn & Suites Salem near I-57
- Hampton Inn Carbondale
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Americas Best Value Inn Marion, IL
- Motel 6 Marion, IL
- Country Garden & Suites
- Best Western Plus Centralia Hotel & Suites
- Motel 6 Troy, IL
- University Inn of Carbondale
- Days Inn & Suites by Wyndham Caseyville
- Indian Mound Motel
- Fairfield Inn and Suites by Marriott Marion
- DoubleTree by Hilton Collinsville - St. Louis
- Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel
- Best Western U. S. Inn