Find 5 Star Hotels in Santa Cruz from SAR 267

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Check availability on Santa Cruz 5 Star Hotels

Compare Santa Cruz 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Marriott Santa Cruz de la Sierra Hotel
Outdoor pool, pool umbrellas, sun loungers

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
9.0 out of 10, Wonderful, (184)
"Quiet place. Very safe and clean."
The price is SAR 416
SAR 416 total
includes taxes & fees
4 Apr - 5 Apr
Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
2 outdoor pools

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
9.0 out of 10, Wonderful, (312)
"Very good quality hotel in beautiful Santa Cruz, Bolivia. Friendly staff Clean grounds "
The price is SAR 469
SAR 469 total
includes taxes & fees
31 Mar - 1 Apr
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Camino Real Hotel
Indoor pool, outdoor pool, pool umbrellas

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (377)
"Superb Hotel. Lovely staff Pool area great. Close to everything in a good area. "
The price is SAR 423
SAR 423 total
includes taxes & fees
28 Mar - 29 Mar
Camino Real Hotel
Sun Hotel
Outdoor pool

Sun Hotel

3.5 star property
8.2 out of 10, Very Good, (284)
"Super easy check in, most of the details are handled by Expedia. It’s a great place to relax before an early morning flight out of VVI. Clean, comfortable and everything you need. "
The price is SAR 405
SAR 405 total
includes taxes & fees
26 Mar - 27 Mar
Sun Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Breakfast, lunch and dinner served

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (226)
"It was OK stay. The staff didn't speak English very well though"
The price is SAR 282
SAR 282 total
includes taxes & fees
29 Mar - 30 Mar
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Novotel Santa Cruz De La Sierra
Lobby sitting area

Novotel Santa Cruz De La Sierra

5.0 star property
9.2 out of 10, Wonderful, (86)
"Great hotel and location also very nice staff."
The price is SAR 281
SAR 281 total
includes taxes & fees
30 Mar - 31 Mar
Novotel Santa Cruz De La Sierra
TRYP by Wyndham Santa Cruz
Outdoor pool, open 9:00 AM to 10:00 PM, free cabanas

TRYP by Wyndham Santa Cruz

4.0 star property
9.4 out of 10, Exceptional, (111)
"Nice stay with good service "
The price is SAR 267
SAR 267 total
includes taxes & fees
26 Mar - 27 Mar
TRYP by Wyndham Santa Cruz
Hotel Cortez
Exterior

Hotel Cortez

3.5 star property
9.0 out of 10, Wonderful, (103)
"Excellent hotel. Nice pool and sauna and small gym - excellent for Bolivia. Friendly staff and decent breakfast. Only gripe is the coffee machine outside the breakfast restaurant: it isn’t free. This is my second stay there in 2 weeks and they had no indication of that the first time. I saw the second time they put a sign saying it was 20bol.. they only charged me 15bol the week prior.. minor detail.. My go to hotel when I arrive in Santa Cruz."
The price is SAR 405
SAR 405 total
includes taxes & fees
28 Mar - 29 Mar
Hotel Cortez
Hotel Maywa
Exterior

Hotel Maywa

4.0 star property
9.2 out of 10, Wonderful, (5)
"Personal atento, buen desayuno continental y habitaciones amplias y modernas "
The price is SAR 165
SAR 165 total
includes taxes & fees
25 Apr - 26 Apr
Hotel Maywa
Hotel Las Américas
Deluxe Suite | Free WiFi

Hotel Las Américas

3.0 star property
The price is SAR 191
SAR 191 total
includes taxes & fees
26 Mar - 27 Mar
Hotel Las Américas
Chairú Eco Hotel
Front of property

Chairú Eco Hotel

3.5 star property
9.4 out of 10, Exceptional, (33)
"The staff was extremely helpful. Due to our flight schedule we arrived 6 hours prior to check-in. Once a room became available that morning after a guest checked out, they got it cleaned immediately and got us in several hours before our actual check in. We were extremely grateful for their kindness. "
The price is SAR 186
SAR 186 total
includes taxes & fees
30 Mar - 31 Mar
Chairú Eco Hotel
Ibis Santa Cruz DE LA Sierra
Sports facility

Ibis Santa Cruz DE LA Sierra

3.0 star property
9.6 out of 10, Exceptional, (41)
"Predictable, good vibe. Very good bed."
The price is SAR 297
SAR 297 total
includes taxes & fees
8 Apr - 9 Apr
Ibis Santa Cruz DE LA Sierra
Hotel Puerta del Rey
Pool

Hotel Puerta del Rey

3.0 star property
4.8 out of 10, (6)
"Simple, clean budget hotel "
The price is SAR 123
SAR 123 total
includes taxes & fees
26 Mar - 27 Mar
Hotel Puerta del Rey
Hotel G
Comfort Room | Private kitchen | Mini-fridge, dining tables

Hotel G

3.5 star property
7.8 out of 10, Good, (102)
"excelente ubicación, muy cómodo el lugar."
The price is SAR 158
SAR 158 total
includes taxes & fees
26 Mar - 27 Mar
Hotel G
Hotel LP Santa Cruz Centro
Standard Room, 2 Twin Beds | Premium bedding, minibar, in-room safe, desk

Hotel LP Santa Cruz Centro

3.0 star property
7.8 out of 10, Good, (277)
"Clean, friendly staff"
The price is SAR 173
SAR 192 total
includes taxes & fees
27 Mar - 28 Mar
Hotel LP Santa Cruz Centro
Lido Hotel
Reception

Lido Hotel

3.0 star property
8.6 out of 10, Excellent, (8)
"The customers service was excellent. The room very comfortable."
The price is SAR 172
SAR 172 total
includes taxes & fees
28 Mar - 29 Mar
Lido Hotel
Buganvillas Hotel Suites & Spa
Aerial view

Buganvillas Hotel Suites & Spa

4.0 star property
7.4 out of 10, Good, (90)
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING "
The price is SAR 225
SAR 225 total
includes taxes & fees
28 Mar - 29 Mar
Buganvillas Hotel Suites & Spa
Hostal Killa
Terrace/patio

Hostal Killa

3.0 star property
The price is SAR 94
SAR 94 total
includes taxes & fees
26 Mar - 27 Mar
Hostal Killa
Hotel LP Equipetrol
Front of property - evening/night

Hotel LP Equipetrol

3.5 star property
8.2 out of 10, Very Good, (198)
"So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good. "
The price is SAR 238
SAR 257 total
includes taxes & fees
28 Mar - 29 Mar
Hotel LP Equipetrol
Swissôtel Santa Cruz De La Sierra
Massages

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (75)
"Beautiful hotel"
The price is SAR 483
SAR 483 total
includes taxes & fees
8 Apr - 9 Apr
Swissôtel Santa Cruz De La Sierra
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Cruz.
Camino Real Hotel

Camino Real Hotel

Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is SAR 423 per night from Mar 28 to Mar 29
SAR 423
SAR 423 total
includes taxes & fees
28 Mar - 29 Mar
8.8/10 Excellent! (377 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Experience Bolivia as the locals see it in the country’s busiest city, where the museums, public squares and churches give you a glimpse into their everyday lives.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Frequently asked questions

What are the best 5-star hotels in Santa Cruz?
If you’re looking for a 5-star experience, Marriott Santa Cruz de la Sierra Hotel offers one of the best of them according to Expedia customer reviews. Book a room at this Santa Cruz getaway and look forward to amazing guest services, well-appointed guest rooms and superior amenities.
How much does it cost to stay in a 5-star hotel in Santa Cruz?
How much you pay for a 5-star hotel in Santa Cruz depends on factors like when you plan to go and the length of your escape. Our insider tip for landing an awesome deal? Use our pricing filters to check out all of the available hotels for your chosen dates.

  • Search for the lowest price per night from SAR 267

What makes a hotel 5 stars in Santa Cruz?
In Santa Cruz, a hotel is required to offer a specific level of upscale features to be rated 5 stars. These may include gourmet restaurants, on-site gyms, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their superior service. You can expect things like concierge services, nightly turn-down services and in-room massage. Some may even offer thoughtful touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Santa Cruz?
Find a luxury getaway that includes your lodging, food, activities and entertainment in Santa Cruz with the help of Expedia’s filter tool. Search for resorts with a 5-star rating and select the “All inclusive” filter. Make sure you check what’s included in the upfront price. This way, you can take full advantage of all the perks on offer when you arrive.
What are the top 5-star spa hotels in Santa Cruz?
For a rejuvenating stay in Santa Cruz, you can’t beat Marriott Santa Cruz de la Sierra Hotel. Check in to this 5-star spa property and unwind while spoiling yourself with its well-being programs and treatments.
Are there any 5-star vacation rentals in Santa Cruz?
Our site doesn’t offer any 5-star vacation rentals in Santa Cruz. However, you can still find some top-rated properties where the only item on your itinerary will be to relax and have fun. See what’s available by searching through our vacation rentals in Santa Cruz.
Are there any 5-star hotels in downtown Santa Cruz?
Spend your break at Marriott Santa Cruz de la Sierra Hotel and take advantage of being near the sights and sounds of downtown Santa Cruz.