Find Business Hotels in St. George, SC
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on St. George Business Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare St. George Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Quality Inn St George I-95
Quality Inn St George I-95
6.6 out of 10, (470)

Peach Tree Inn
Peach Tree Inn
7.4 out of 10, Good, (112)
The price is SAR 225
SAR 243 total
includes taxes & fees
14 Apr - 15 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about St. George
Find out more about St. George
Recent reviews of St. George hotels
Recent reviews of St. George hotels

Hampton Inn Santee-I-95
5/5 Excellent
"What a fantastic place to stay and right off 95. Very clean, updated, and great staff. Breakfast looked good, although we weren’t hungry so we didn’t partake. This will be our go-to stop on our way to Florida. "
A verified traveler stayed at Hampton Inn Santee-I-95
Posted 4 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near St. George
More Hotel Options in St. George
- Adventure Hotels in St. George
- Cheap Hotels in St. George
- Family Hotels in St. George
- Golf Hotels in St. George
- Hotels with Bars in St. George
- Hotels with Free Parking in St. George
- Hotels with WiFi in St. George
- Hotels with a Pool in St. George
- Hotels with smoking rooms in St. George
- Luxury Hotels in St. George
- Pet-friendly Hotels in St. George
- Shopping Hotels in St. George
More Accommodation Types in St. George
- Condo Rentals in South Carolina
- Vacation Homes in South Carolina
- Apartments in South Carolina
- Villas in South Carolina
- Resorts in South Carolina
- Cottages in South Carolina
- Cabin Rentals in South Carolina
- Aparthotels in South Carolina
- Motels in South Carolina
- B&B in South Carolina
- Guest Houses in South Carolina
- Lodges in South Carolina
- Condo Resorts in South Carolina
- Houseboats in South Carolina
- Inns in South Carolina
- Country Houses in South Carolina
- Hostels in South Carolina
Hotels near popular St. George Attractions
- Hotels near St. George Country Club
- Hotels near St. George United Methodist Church
- Hotels near Jennie J McMahan Library
- Hotels near Santee State Park
- Hotels near Santee Outlets
- Hotels near Santee Cooper Country Club
- Hotels near Santee National Wildlife Refuge
- Hotels near Givhans Ferry State Park
- Hotels near Santee National Golf Club
- Hotels near Legend Oaks Golf Club
St. George Hotels by Star Rating
Explore more hotels
- Comfort Inn & Suites Walterboro I-95
- Holiday Inn Santee by IHG
- Motel 6 Walterboro, SC
- Hampton Inn Santee-I-95
- Holiday Inn Exp Walterboro by IHG
- Microtel Inn & Suites by Wyndham Walterboro
- Best Western Plus Santee Inn
- Comfort Inn & Suites Santee
- Econo Lodge
- Hampton Inn & Suites Walterboro
- Bells Marina & Resort
- Quality Inn
- Travelodge by Wyndham Santee
- Best Western Of Walterboro
- Quality Inn & Suites
- Sleep Inn Walterboro I-95
- Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
- Ramada by Wyndham Santee I-95
- Days Inn by Wyndham Walterboro
- Pet friendly country cottage with large fenced-in yard & horses on property