Find Luxury Hotels in Santo Spirito

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare Santo Spirito Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Palazzo Guicciardini
Room

Palazzo Guicciardini

9.4 out of 10, Exceptional, (142)
"Service was no thrills, but the rooms are excellent. "
The price is SAR 523
SAR 619 total
includes taxes & fees
16 Jan - 17 January 2025
Palazzo Guicciardini
La Terrazza su Boboli
Interior detail

La Terrazza su Boboli

9.6 out of 10, Exceptional, (32)
"An overnight stay as we travelled from Italy to France. A great and comfortable night and fantastic breakfast."
La Terrazza su Boboli
UNAHOTELS Vittoria Firenze
Garden

UNAHOTELS Vittoria Firenze

4.0 star property
8.4 out of 10, Very Good, (1001)
"Reception"
The price is SAR 351
SAR 441 total
includes taxes & fees
26 Jan - 27 January 2025
UNAHOTELS Vittoria Firenze
Convitto della Calza - Holiday Home
Property grounds

Convitto della Calza - Holiday Home

7.8 out of 10, Good, (145)
"Clean, fair for the price Three stars at most Staff were very friendly A short bus ride away from city attractions Bus stop outside the hotel"
Convitto della Calza - Holiday Home
Hotel Palazzo Guadagni
Room amenity

Hotel Palazzo Guadagni

3.0 star property
9.0 out of 10, Wonderful, (186)
"The Hotel is so charming and exactly the vibe you want from Florence. The staff are amazing and they are very helpful guides to the city and have great, chic taste. "
The price is SAR 656
SAR 769 total
includes taxes & fees
6 Jan - 7 January 2025
Hotel Palazzo Guadagni
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santo Spirito

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to Santo Spirito?
Known for its riverfront, Santo Spirito also has some interesting things to see and do including Historic Centre of Florence, so you may want to take in the local sights during your visit.
What's the best high-end hotel in Santo Spirito?
Palazzo Guicciardini is a luxury guesthouse with in-room massages and a bar, and it’s a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels should I expect to find in Santo Spirito?
Lie in the lap of luxury during your getaway to Santo Spirito in one of Expedia’s 11 luxury hotels.
What's the best time to vacation in Santo Spirito?
The hottest months are usually August and July with an average temperature of 72°F,
  • Coldest months: January, February, December, and March
  • Driest months: July, August, June, and April
  • Rainiest months: November, October, December, and February
What's there to see and do in Santo Spirito?
Enjoy all that Santo Spirito has to offer when you visit Historic Centre of Florence, Porta Romana, and Piazza Santo Spirito. If you have a bit of extra time while you’re in the area, you might want to check out Pitti Palace and Santo Spirito Basilica.