Photo by Vivian Rennó

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Compare 50 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hotel Boutique Vendimia Premium

3.5 star property
9.2 out of 10, Wonderful, (131)
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different. "
The price is SAR 268
SAR 268 total
includes taxes & fees
29 Apr - 30 Apr
Hotel Boutique Vendimia Premium

Santa Cruz Plaza

4.0 star property
8.6 out of 10, Excellent, (309)
"It was great, spa, sauna and heated pool was nice touch "
The price is SAR 348
SAR 348 total
includes taxes & fees
18 May - 19 May
Santa Cruz Plaza

La Perla Hotel

3.5 star property
9.2 out of 10, Wonderful, (92)
"Nice stay"
The price is SAR 326
SAR 326 total
includes taxes & fees
23 Apr - 24 Apr
La Perla Hotel

Casa Calfu

3.0 star property
9.8 out of 10, Exceptional, (56)
"This is a really charming bed and breakfast. It is in a secure area and behind a locked gate. They have many amenities that I did not make use of such as a a pool and hot tub. The breakfast was excellent. My room had a very small private terrace with seats for two. There was also a larger terrace off the dining room should you be there with a group. Everything was clean and well maintained."
The price is SAR 377
SAR 377 total
includes taxes & fees
5 May - 6 May
Casa Calfu

Hotel Vendimia Parador

3.0 star property
9.6 out of 10, Exceptional, (75)
"Great place for a weekend of wines and relax. My gf and I really enjoyed the facilities, good breakfast, owners provide great customer service. "
The price is SAR 268
SAR 268 total
includes taxes & fees
22 May - 23 May
Hotel Vendimia Parador

Hotel Cava Colchagua

4.0 star property
9.0 out of 10, Wonderful, (153)
"Fun, interesting, pools ice cold, dogs barking all night. Still you don’t want to miss this opportunity."
The price is SAR 583
SAR 583 total
includes taxes & fees
30 Apr - 1 May
Hotel Cava Colchagua

TerraViña

3.0 star property
9.2 out of 10, Wonderful, (193)
"Great hotel in the Colchagua valley. Rooms are spacious and clean. Grounds are beautiful and the pool is restful! Staff are friendly and always eager to help. The restaurant serves tasty food and many wine options. "
The price is SAR 425
SAR 425 total
includes taxes & fees
6 May - 7 May
TerraViña

Hotel Boutique Solaz Bella Vista de Colchagua

3.0 star property
9.4 out of 10, Exceptional, (96)
"Really recommended. Breakfast is very good, staff is amazing. A jewel close to the vineyards. Nice for romantic retreat."
The price is SAR 294
SAR 294 total
includes taxes & fees
5 May - 6 May
Hotel Boutique Solaz Bella Vista de Colchagua

Hotel Boutique Grand Cru

3.0 star property
10.0 out of 10, Exceptional, (3)
"We had such a wonderful stay! The staff was so attentive and the room was impeccable! I highly recommend this hotel."
The price is SAR 410
SAR 410 total
includes taxes & fees
25 Apr - 26 Apr
Hotel Boutique Grand Cru

Noi Blend Colchagua

3.0 star property
9.0 out of 10, Wonderful, (126)
"It’s a very special place! It’s very difficult to photograph but it’s charming, authentic and wonderful. We booked dinner in Santa Cruz (and they arranged transportation for us) but after having breakfast there, we should have eaten there! It was great. This place is a quaint, hidden gem!"
The price is SAR 490
SAR 490 total
includes taxes & fees
28 Apr - 29 Apr
Noi Blend Colchagua

Vik Chile

5.0 star property
9.2 out of 10, Wonderful, (119)
"The grounds are transcendent. We felt like we were on top of the world with the location of the hotel on the hill and the views were magnificent. The staff was courteous. The food was Michelin Star quality."
The price is SAR 3,602
SAR 3,602 total
includes taxes & fees
5 May - 6 May
Vik Chile

Hotel Viña La Playa

3.5 star property
8.2 out of 10, Very Good, (17)
"Property has a lot of character, very clean, very pleasant and helpful staff. Great breakfast."
The price is SAR 769
SAR 769 total
includes taxes & fees
5 May - 6 May
Hotel Viña La Playa

Hotel Ontiveros

3.5 star property
9.4 out of 10, Exceptional, (20)
"I'm not sure why this hotel is rated so highly. I would call it just so-so. The rooms are in bad need of updating, and it took forever for the heater to warm the room. Perhaps it's the best thing in San Fernando? I was hoping that since the property had a conference center the staff would speak English, however that was not the case. The staff were extremely nice however. The breakfast consisted of cold meats, cheeses, pies and pastries, and instant coffee. Not the best, however when I asked...
The price is SAR 302
SAR 302 total
includes taxes & fees
25 Apr - 26 Apr
Hotel Ontiveros

Hotel Boutique Raices

3.5 star property
9.4 out of 10, Exceptional, (33)
"An amazingly jewel of a hotel in the center of it all. We will return!"
The price is SAR 374
SAR 434 total
includes taxes & fees
5 May - 6 May
Hotel Boutique Raices
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Get away to relaxing Santa Cruz! Enjoy the wineries, local cuisine, and countryside.

Amazing place to relax and enjoy the view after tasting good wine...
Photo by Vivian Rennó
Open Photo by Vivian Rennó

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Hotel Vendimia Parador is a favorite property for Expedia customers. This hotel offers an outdoor pool and an indoor pool. Reviews from our site also recommend La Perla Hotel and TerraViña as top choices for your visit. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best vacation home rentals that Santa Cruz has to offer?

Hosteria No me Olvides: This vacation home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Another good choice for your trip to Santa Cruz is The ambush. Field and comfort. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To access more information about changing or cancelling your trip to Santa Cruz, head over to our customer service page.

What's the best budget-friendly hotel in Santa Cruz?

Based on our traveler reviews, Hostal Gomero is a top choice for a less expensive stay. Other choices to stay on the cheap include Casa Suiza - Hostel and Hostal Cepa Noble. View all budget hotels in Santa Cruz.

What's the best hotel for families in Santa Cruz?

Santa Cruz Plaza is a hotel with an outdoor pool and a free kids' club, and it's a top choice on Expedia for families. Kids of all ages will also enjoy a visit to Colchagua Campo y Vino. Find more child-friendly accommodations in Santa Cruz.

What's the best pet-friendly place to stay in Santa Cruz?

Hotel Vendimia Parador is a top hotel for people traveling with their pets, and offers an indoor pool and an outdoor pool for its human guests. Two other good options for you and your pet's trip include Parcela con tranque, sala de juegos, terraza, and Hotel Hoja de Parra. See more pet-friendly hotel accommodations in Santa Cruz.

Where is the best place to stay close to Plaza de Armas?

Adjacent to Plaza de Armas, Santa Cruz Plaza is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers a full-service spa and a restaurant. Other good choices close by include Intown Apart Santa Cruz and Tierra y Vino.

What about the best place to stay close to Museo de Colchagua?

One of the top choices for your stay is Santa Cruz Plaza, located next to Museo de Colchagua, and this 4-star hotel offers a full-service spa and a restaurant. La Perla Hotel and Tierra y Vino are two other good choices in the immediate area.

What are some accommodations with pools in Santa Cruz?

Hotel Vendimia Parador is a top hotel with an indoor pool, an outdoor pool, and free WiFi. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Santa Cruz Plaza is a top spa hotel featuring a rooftop terrace, a 24-hour fitness center, a free kid's club, and a bar. Treat yourself to a facial, body scrub, or hydrotherapy at the onsite spa. Other popular spa hotels in Santa Cruz include Hotel Cava Colchagua and Hotel Boutique Solaz Bella Vista de Colchagua. See all spa hotels in Santa Cruz.

What is the best accommodation for staying close to Arturo Merino Benitez Airport (SCL)?

Holiday Inn Santiago - Airport Terminal is a popular 3.5-star hotel featuring free extended parking and a restaurant. It's located a short 0.1 mi (0.2 km) from Arturo Merino Benitez Airport. Other good choices near the airport include Hotel Diego de Almagro Aeropuerto - Santiago and City Express Santiago Aeropuerto.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz are sure to enjoy the wineries, local tours, and restaurants. Tourists can also enjoy so much more including its casinos. In Santa Cruz, there are 32 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Wine tasting is a great activity, and Lapostolle Clos Apalta Winery is one place to visit. A couple of additional sights to add to your agenda are Casino Colchagua and Colchagua Campo y Vino. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually January and February with an average temp of 70°F, while the coldest months are July and August with an average of 50°F. Average annual precipitation for Santa Cruz is 29 inches.