Photo by Vivian Rennó

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Compare 62 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Santa Cruz Plaza

4.0 star property
8.6 out of 10, Excellent, (300)
"Nice well located with bar and good restaurante"
The price is SAR 411
SAR 411 total
includes taxes & fees
2 Mar - 3 Mar
Santa Cruz Plaza

Hotel Boutique Solaz Bella Vista de Colchagua

3.0 star property
9.4 out of 10, Exceptional, (95)
"Great value for the money. You will need a car as nothing is walkable. Staff very friendly. Rooms on the frugal side yet super clean. "
The price is SAR 294
SAR 294 total
includes taxes & fees
18 Mar - 19 Mar
Hotel Boutique Solaz Bella Vista de Colchagua

Hotel Cava Colchagua

4.0 star property
8.8 out of 10, Excellent, (148)
"Literally set in a vineyard the rooms could be twee being set in ( very large) upturned wine barrels, but is fun. Noting though that there really is no soundproofing so as we were pretty much the only people there perhaps things change with more guests"
The price is SAR 469
SAR 469 total
includes taxes & fees
23 Mar - 24 Mar
Hotel Cava Colchagua

Hotel Boutique Vendimia Premium

3.5 star property
9.2 out of 10, Wonderful, (131)
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different. "
The price is SAR 335
SAR 335 total
includes taxes & fees
2 Mar - 3 Mar
Hotel Boutique Vendimia Premium

Hotel Vendimia Parador

3.0 star property
9.6 out of 10, Exceptional, (72)
"Absolutely lovely place to stay! Beautiful home. The staff were wonderful. Easy reach of vineyards, but so nice to rest, swim and be spoilt by the staff."
The price is SAR 346
SAR 346 total
includes taxes & fees
24 Mar - 25 Mar
Hotel Vendimia Parador

TerraViña

3.0 star property
9.2 out of 10, Wonderful, (189)
"Situated in the middle of wineries, away from the hustle bustle - TerraVina is a beautiful property with rooms with a balcony facing the Andes. There is a terrific winery just a 5 to 8 minute walk and three restaurants within 5 minutes, one located directly within the property. "
The price is SAR 675
SAR 675 total
includes taxes & fees
2 Mar - 3 Mar
TerraViña

Casa Calfu

3.0 star property
9.6 out of 10, Exceptional, (55)
"Cozy, very well kept property with excellent service "
The price is SAR 365
SAR 365 total
includes taxes & fees
4 Mar - 5 Mar
Casa Calfu

La Perla Hotel

3.5 star property
9.0 out of 10, Wonderful, (87)
"Friendly staff, Quiet and Safe. Clean rooms. Hot tub and pool not available when we were there (spring time)."
The price is SAR 410
SAR 410 total
includes taxes & fees
2 Mar - 3 Mar
La Perla Hotel

Hotel Boutique Grand Cru

3.0 star property
The price is SAR 354
SAR 354 total
includes taxes & fees
31 Mar - 1 Apr
Hotel Boutique Grand Cru

Hotel Ontiveros

3.5 star property
9.4 out of 10, Exceptional, (20)
"I'm not sure why this hotel is rated so highly. I would call it just so-so. The rooms are in bad need of updating, and it took forever for the heater to warm the room. Perhaps it's the best thing in San Fernando? I was hoping that since the property had a conference center the staff would speak English, however that was not the case. The staff were extremely nice however. The breakfast consisted of cold meats, cheeses, pies and pastries, and instant coffee. Not the best, however when I asked...
The price is SAR 388
SAR 388 total
includes taxes & fees
10 Mar - 11 Mar
Hotel Ontiveros

Vik Chile

5.0 star property
9.2 out of 10, Wonderful, (110)
"The grounds are transcendent. We felt like we were on top of the world with the location of the hotel on the hill and the views were magnificent. The staff was courteous. The food was Michelin Star quality."
The price is SAR 5,241
SAR 5,241 total
includes taxes & fees
13 Mar - 14 Mar
Vik Chile

Hotel Boutique Raices

3.5 star property
9.4 out of 10, Exceptional, (31)
"Super friendly staff"
The price is SAR 379
SAR 440 total
includes taxes & fees
4 Mar - 5 Mar
Hotel Boutique Raices

Hotel Viña La Playa

3.5 star property
8.2 out of 10, Very Good, (17)
"Property has a lot of character, very clean, very pleasant and helpful staff. Great breakfast."
Hotel Viña La Playa

Noi Blend Colchagua

3.0 star property
9.0 out of 10, Wonderful, (119)
"Lovely hotel in the Santa Cruz area, convenient to many of the local wineries. The majority staff were not as attentive and 'on the ball' as others we encountered in Chile, but we still had a lovely stay. The pool area was a lovely space to chill out and it was always very quiet. The breakfasts were good, but the other meals were 'below par', I wouldn't suggest planning to eat your main meals at the hotel."
The price is SAR 624
SAR 624 total
includes taxes & fees
2 Mar - 3 Mar
Noi Blend Colchagua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Get away to relaxing Santa Cruz! Enjoy the wineries, local cuisine, and casinos.

Amazing place to relax and enjoy the view after tasting good wine...
Photo by Vivian Rennó
Open Photo by Vivian Rennó

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Casa Calfu is a favorite property for Expedia customers. This B&B offers free breakfast and an outdoor pool. Reviews from our site also recommend La Perla Hotel and TerraViña as top choices for your visit. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best vacation home rentals that Santa Cruz has to offer?

Hosteria No me Olvides: This vacation home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Another good choice for your trip to Santa Cruz is The ambush. Field and comfort. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To access more information about changing or cancelling your trip to Santa Cruz, head over to our customer service page.

What's the best budget-friendly hotel in Santa Cruz?

Based on our traveler reviews, Casa Suiza - Hostel is a top choice for a less expensive stay. Other options for your budget-friendly stay include Hostal Cepa Noble and Hostal Casa Familia. View all budget hotels in Santa Cruz.

What's the best hotel for families in Santa Cruz?

Santa Cruz Plaza is a hotel with an outdoor pool and a free kids' club, and it's a top choice on Expedia for families. Kids of all ages will also enjoy a visit to Colchagua Campo y Vino. Find more child-friendly accommodations in Santa Cruz.

What's the best pet-friendly place to stay in Santa Cruz?

Hotel Vendimia Parador is a top hotel for people traveling with their pets, and offers an indoor pool and an outdoor pool for its human guests. Two other good options for you and your pet's trip include Parcela con tranque, sala de juegos, terraza, and Hotel Hoja de Parra. See more pet-friendly hotel accommodations in Santa Cruz.

Where is the best place to stay close to Plaza de Armas?

Adjacent to Plaza de Armas, Santa Cruz Plaza is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers a full-service spa and a restaurant. Other good choices close by include Intown Apart Santa Cruz and Tierra y Vino.

What about the best place to stay close to Museo de Colchagua?

One of the top choices for your stay is Santa Cruz Plaza, located next to Museo de Colchagua, and this 4-star hotel offers a full-service spa and a restaurant. La Perla Hotel and Tierra y Vino are two other good choices in the immediate area.

What are some accommodations with pools in Santa Cruz?

Hotel Vendimia Parador is a top hotel with an indoor pool, an outdoor pool, and free WiFi. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Hotel Cava Colchagua is a top spa hotel featuring a vineyard, a bar, an outdoor pool, and a restaurant. Treat yourself to a couples treatment, massage, or the hot springs at the onsite spa. Other popular spa hotels in Santa Cruz include Santa Cruz Plaza and Hotel Boutique Solaz Bella Vista de Colchagua. See all spa hotels in Santa Cruz.

What is the best accommodation for staying close to Arturo Merino Benitez Airport (SCL)?

Holiday Inn Santiago - Airport Terminal is a popular 3.5-star hotel featuring free extended parking and a restaurant. It's located a short 0.1 mi (0.2 km) from Arturo Merino Benitez Airport. Other good choices near the airport include Hotel Diego de Almagro Aeropuerto - Santiago and City Express Santiago Aeropuerto.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz are sure to enjoy the wineries, local tours, and restaurants. Tourists can also enjoy so much more including its casinos. In Santa Cruz, there are 35 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Wine tasting is a great activity, and Lapostolle Clos Apalta Winery is one place to visit. A couple of additional sights to add to your agenda are Casino Colchagua and Colchagua Campo y Vino. Check out what more to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually January and February with an average temp of 70°F, while the coldest months are July and August with an average of 50°F. Average annual precipitation for Santa Cruz is 29 inches.