Otay Mesa West Vacations

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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
US Grant Hotel

Downtown San Diego

3 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego

Otay Mesa West Hotel Deals

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is SAR 425 per night from Apr 22 to Apr 23
SAR 425
SAR 479 total
includes taxes & fees
22 Apr - 23 Apr
7.8/10 Good! (1,443 reviews)
"My room was nice and clean. I just didn’t really like the noise from the freeway but that’s to be expected."

Reviewed on 7 April 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is SAR 710 per night from Apr 20 to Apr 21
SAR 710
SAR 969 total
includes taxes & fees
20 Apr - 21 Apr
8.2/10 Very Good! (1,160 reviews)
"Although the hotel is aesthetically pleasing and the staff is exceptional, it is imperative that the mattresses are upgraded. During my two-night stay, I encountered springs protruding in the mattress, making it very uncomfortable to sleep for my wife and I."

Reviewed on 6 April 2025

San Diego Mission Bay Resort
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is SAR 571 per night from Apr 17 to Apr 18
SAR 571
SAR 644 total
includes taxes & fees
17 Apr - 18 Apr
8.2/10 Very Good! (5,668 reviews)
"great location"

Reviewed on 7 April 2025

Wyndham San Diego Bayside
See all 6,539 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Otay Mesa West

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

4.5/5(3,565 reviews)

Why not visit the animals who live at San Diego Zoo and see why this is a favorite attraction in San Diego? Stroll along the area's seaside or experience its acclaimed theater scene.

San Diego Zoo
San Diego Convention Center

San Diego Convention Center

4.5/5(1,297 reviews)

During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.

San Diego Convention Center
Mission Bay featuring a sandy beach

Mission Bay

4.5/5(2,386 reviews)

Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.

Mission Bay