Otay Mesa West Vacations

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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego

Otay Mesa West Hotel Deals

San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is SAR 747 per night from Apr 29 to Apr 30
SAR 747
SAR 1,010 total
includes taxes & fees
29 Apr - 30 Apr
8.2/10 Very Good! (1,191 reviews)
"I have been coming to this property since the 80's when I was a child with my parents. This place still is just amazing. What I like best about it is the feeling that you are on some tropical island enjoying breathtaking views of the harbor. What is also nice is it's location is perfect for families ..."

Reviewed on 25 April 2025

San Diego Mission Bay Resort
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is SAR 495 per night from May 6 to May 7
SAR 495
SAR 569 total
includes taxes & fees
6 May - 7 May
7.8/10 Good! (1,540 reviews)
"All was great"

Reviewed on 27 April 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is SAR 571 per night from May 11 to May 12
SAR 571
SAR 662 total
includes taxes & fees
11 May - 12 May
8.2/10 Very Good! (5,682 reviews)
"The accommodations for upgrades"

Reviewed on 27 April 2025

Wyndham San Diego Bayside
See all 6,590 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Otay Mesa West

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

4.5/5(3,565 reviews)

Why not visit the animals who live at San Diego Zoo and see why this is a favorite attraction in San Diego? Stroll along the area's seaside or experience its acclaimed theater scene.

San Diego Zoo
San Diego Convention Center

San Diego Convention Center

4.5/5(1,297 reviews)

During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.

San Diego Convention Center
Mission Bay featuring a sandy beach

Mission Bay

4.5/5(2,386 reviews)

Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.

Mission Bay