Find hotels in Main South, Worcester from SAR 297
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Discover 311 Main South hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn Boston Milford
Comfort Inn Boston Milford
7.2 out of 10, Good, (1000)
The price is SAR 436
SAR 486 total
includes taxes & fees
27 May - 28 May

DoubleTree by Hilton Boston - Milford
DoubleTree by Hilton Boston - Milford
8.4 out of 10, Very Good, (925)
The price is SAR 491
SAR 548 total
includes taxes & fees
27 May - 28 May

Holiday Inn Express Boston - Milford by IHG
Holiday Inn Express Boston - Milford by IHG
8.6 out of 10, Excellent, (1001)
The price is SAR 503
SAR 561 total
includes taxes & fees
7 May - 8 May

Fairfield Inn & Suites by Marriott Boston Milford
Fairfield Inn & Suites by Marriott Boston Milford
8.2 out of 10, Very Good, (765)
The price is SAR 435
SAR 486 total
includes taxes & fees
26 May - 27 May

Sonesta Select Boston Milford
Sonesta Select Boston Milford
8.4 out of 10, Very Good, (976)
The price is SAR 544
SAR 608 total
includes taxes & fees
1 May - 2 May

Sheraton Framingham Hotel & Conference Center
Sheraton Framingham Hotel & Conference Center
8.0 out of 10, Very Good, (1000)
The price is SAR 668
SAR 746 total
includes taxes & fees
30 May - 31 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Where to stay in Main South
Where to stay in Main South
Hotels in top Worcester neighborhoods Learn more about Main South

Worcester Central Business District
4 out of top 10 points of interest in this area
4/5(116 area reviews)
If you're spending some time in Worcester Central Business District, DCU Center and Mechanics Hall are top sights worth seeing.
Recent reviews of Main South hotels
Recent reviews of Main South hotels

Publick House Historic Inn and Country Motor Lodge
5/5 Excellent
"We stayed one night and it was beautiful. The room was clean, quiet and comfortable and the assortment of fresh complimentary pastries and muffins were delicious. Would definitely stay again! "
A verified traveler stayed at Publick House Historic Inn and Country Motor Lodge
Posted 23 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Worcester neighborhoods
Hotels near popular Worcester Attractions
- Hotels near Clark University
- Hotels near Burnside Fountain
- Hotels near DCU Center
- Hotels near Old Sturbridge Village
- Hotels near Union Station
- Hotels near Apex Entertainment Center
- Hotels near College of the Holy Cross
- Hotels near Worcester Polytechnic Institute
- Hotels near New England Sports Center
- Hotels near Wachusett Mountain Ski Area
More Accommodation Types in Main South
Hotels Close to Nearby Airports
- Hotels near Logan Intl. Airport
- Hotels near Boston Harbor Seaplane Base Airport
- Hotels near Portsmouth Intl. Airport
- Hotels near Worcester Regional Airport
- Hotels near Marlborough Airport
- Hotels near Minute Man Air Field Airport
- Hotels near North Central State Airport
- Hotels near Waltham Airport
- Hotels near Laurence G. Hanscom Field Airport
Main South Hotels by Star Rating
Main South Hotels by Brand
Explore more hotels
- Extended Stay America Suites Boston Marlborough
- AC Hotel by Marriott Worcester
- Extended Stay America Suites Boston Westborough Computer Dr
- Hampton Inn Boston/Marlborough
- La Quinta Inn & Suites by Wyndham Sturbridge
- Hilton Garden Inn Boston/Marlborough
- Hampton Inn & Suites Worcester
- Sonesta Select Boston Milford
- Courtyard by Marriott Worcester
- DoubleTree by Hilton Boston - Milford
- Fairfield Inn & Suites by Marriott Worcester Auburn
- Holiday Inn Express Hotel & Suites Auburn by IHG