Search Vacation Homes in Eastern Panama

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Compare 31 Vacation Homes in Eastern Panama with updated reviews, rates, and availability.

Spacious Beach House on the ocean front with huge pool and patio.

8.0 out of 10, Very Good, (6)
"Very spacious and comfortable home…the best part was the pool and the view! Very safe complex, super attentive and responsive staff (Maria was great!). Everything in the home worked properly and the entire process from booking to checking out was very smooth. Definitely recommend!."
Spacious Beach House on the ocean front with huge pool and patio.

Cabaña La Punta op het Strand!!

The price is SAR 488
SAR 638 total
includes taxes & fees
24 Feb - 25 Feb
Cabaña La Punta op het Strand!!

Casa Anzuelo is an oceanfront home that is all about the water and nature.

10.0 out of 10, Exceptional, (15)
"Jim was a superb host and the accommodation is really nice with everything you need for a comfortable stay. The village is simple and friendly and the wildlife great - monkeys and sloths. The lagoon and reef outside the property is really interesting. Will stay again."
Casa Anzuelo is an oceanfront home that is all about the water and nature.

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

The price is SAR 1,125
SAR 1,451 total
includes taxes & fees
24 Feb - 25 Feb
Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Casa Frente al Mar - Isla Grande

10.0 out of 10, Exceptional, (1)
"All perfect "
Casa Frente al Mar - Isla Grande

Round House River Dreams Cerro Azul

Round House River Dreams Cerro Azul

Casa Dinis - Casa Grande - Centro DE Portobelo

The price is SAR 1,781
SAR 2,250 total
includes taxes & fees
24 Feb - 25 Feb
Casa Dinis - Casa Grande - Centro DE Portobelo

Caribbean Paradise - Beachfront Getaway

The price is SAR 1,406
SAR 1,826 total
includes taxes & fees
4 Mar - 5 Mar
Caribbean Paradise - Beachfront Getaway

Despierta sobre el mar

2.0 star property
6.0 out of 10, (1)
The price is SAR 281
SAR 403 total
includes taxes & fees
28 Feb - 1 Mar
Despierta sobre el mar

Nice house in Portobelo, Skybluebyguanche

The price is SAR 506
SAR 581 total
includes taxes & fees
28 Feb - 1 Mar
Nice house in Portobelo, Skybluebyguanche

A fantastic place between the sea and the jungle

10.0 out of 10, Exceptional, (4)
"La comunicación con los anfitriones siempre fue buena, siempre atentos, recibíamos respuesta inmediata a cualquier consulta. La atencion muy buena, Chente y Laura estaban atentos a todo lo que se necesitara. Lindas vistas y muy cómodas las cabañas. Recomendado!!"
A fantastic place between the sea and the jungle

Tudor Mountain Retreat

10.0 out of 10, Exceptional, (1)
"I brought several people to Panama for an entomology research project I am conducting with the University of Panama and Mississippi State University, and we stayed for a week in this fantastic home. I had people from Italy, Germany, Switzerland, and Canada. They were extremely glad I was able to get this home for part of their stay in Panama. "
Tudor Mountain Retreat

Dreamy, Modern Caribbean Home at Playa Escondida

8.0 out of 10, Very Good, (1)
"Overall, we enjoyed our stay here. The unit is modern and clean. There were a few minor issues. We would have appreciated having a role of paper towel to be provided. We forgot to get one and it is quite a drive to the nearest grocery store. There was a vent in the ceiling, above the front door, that was dripping water on the floor."
Dreamy, Modern Caribbean Home at Playa Escondida

Cara al mar Cacique

10.0 out of 10, Exceptional, (1)
"Rachel (the property owner) is the BEST! The car I rented couldn’t get up the steep driveway and she was there immediately to offer help. The views from the house are spectacular. We spent most of our time outside because there is a nice breeze off the ocean. I can hear howler monkeys. "
Cara al mar Cacique

Paraiso de Ensueño Caribeño

10.0 out of 10, Exceptional, (2)
"If enjoy and appreciate nature this is a wonderful place. You have all the basics necessary for unforgettable stay. The local people are very nice and welcoming. The see is magnificent.! "
Paraiso de Ensueño Caribeño

San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

9.0 out of 10, Wonderful, (4)
"Great views and a relaxing time was had at this comfortable sea side duplex. We were the only renters so we had the whole yard and pool to ourselves. Bob was an excellent resident owner host and the support staff of Maria and Ilariao were perfect and there when we needed help. Getting to Michi was an adventure especially at night and at the end of Mardi Gras...the road and the citizens were a challenge. After we got the lay of the land driving the area and meeting the residents of the Portobelo...
San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

The house is beautiful but de best is the lake to do fishing

10.0 out of 10, Exceptional, (1)
"Great. Please take care of the cat"
The house is beautiful but de best is the lake to do fishing

Hacienda mi Montañita

3.0 star property
6.0 out of 10, (5)
"This was a beautiful property when it comes to been in the clouds and as close to nature as possible. The wind is loud at nighttime and whistles through the house all night; making it difficult to sleep. I booked through Expedia and the owner said she did not receive my reservation. I had made this reservation a month before travel to celebrate my daughters 15th birthday. I am glad she was able to find accommodations for us and my family loved waking up in nature everyday. We also loved the...
Hacienda mi Montañita

HERMOSA Y COMODA CASA EN LAS COSTAS DEL MAR CARIBE<br><br>IN FRONT OF THE SEA

5.4 out of 10, (3)
"What a fantastic property! You could not ask for more if you plan to stay on the Caribbean side of Panama... Casa Buenaventura was perfect for our troop of 4 adults and 5 children. Clean, well appointed, lots of space... and Gabriel was the best! He met us personally upon check in to show the house, provide us with a full itinerary for 5 days of fun, beaches, private boat tour, short trips along the coast, snorkeling, and more! Additionally, Gabriel was only a quick What'sApp text away with any...
The price is SAR 938
SAR 1,058 total
includes taxes & fees
24 Feb - 25 Feb
HERMOSA Y COMODA CASA EN LAS COSTAS DEL MAR CARIBE<br><br>IN FRONT OF THE SEA

Private cabin in San Blas

The price is SAR 994
SAR 1,121 total
includes taxes & fees
24 Feb - 25 Feb
Private cabin in San Blas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Eastern Panama
Save an average of 15% on thousands of hotels when you're signed in

Other property types in Eastern Panama

Private Over the Water Cabin on San Blas Island

2.0 star property
6.4 out of 10, (5)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were off hinge and barely closed. The shower and sink were filthy and the toilet stained. The water smelled strongly of sulpher so we did not shower nor use it for anything other than a hand wash. Food was...
Private Over the Water Cabin on San Blas Island

San Blas Tour Aridub

2.0 star property
The price is SAR 321
SAR 540 total
includes taxes & fees
9 Mar - 10 Mar
San Blas Tour Aridub

San Blas Private Beach Cabin

2.5 star property
The price is SAR 971
SAR 1,443 total
includes taxes & fees
25 Feb - 26 Feb
San Blas Private Beach Cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.