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Compare 224 Vacation Homes in Depew with updated reviews, rates, and availability.

On the Niagara River - River Access DOCK - POOL - HOT TUB - FIREPIT and more

10.0 out of 10, Exceptional, (143)
"Had a great weekend!! Grabbed a Buffalo Bills game, easy commute to the game from the house!! Thanks for a great stay Glen!"
On the Niagara River - River Access DOCK - POOL - HOT TUB - FIREPIT and more

Convenient 3-bedroom house with AC, WiFi in peaceful Bowmansville

Convenient 3-bedroom house with AC, WiFi in peaceful Bowmansville

Beautiful furnished 2 bdr great location Elmwood

9.4 out of 10, Exceptional, (28)
"Great clean place close to everything! I’ll be back…"
Beautiful furnished 2 bdr great location Elmwood

Living Large Downtown

Living Large Downtown

Cute n spacious Westbrook home very close to Buffalo Int Airport and everywhere!

2.0 star property
8.0 out of 10, Very Good, (1)
Cute n spacious Westbrook home very close to Buffalo Int Airport and everywhere!

Cozy Home in Cheektowaga

10.0 out of 10, Exceptional, (2)
"It was amazing! Quick responses and had room for our dog. It was cozy and comfortable and location for food/stadium/airport/highway was perfect! We had such a good time! "
Cozy Home in Cheektowaga

This spacious, pristine 3 bedroom retreat is ideal for families & larger groups

10.0 out of 10, Exceptional, (10)
"We were in town for a family wedding and this place was perfect for young kids and adults as well! Would highly recommend "
The price is SAR 1,085
SAR 2,005 total
includes taxes & fees
6 Jan - 7 Jan
This spacious, pristine 3 bedroom retreat is ideal for families & larger groups

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

2.0 star property
10.0 out of 10, Exceptional, (11)
"We absolutely loved our stay at this beautifully remodeled historic home. It was perfect for our family, offering a blend of charming history and modern updates. It had a pack n play for kid, nice coffee/berverage area, large tv, work desk/ library area. Good for remote work while visiting family."
Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

4 bedrooms & 3 bathrooms | Entire Home For Families 🏠

9.6 out of 10, Exceptional, (41)
"I would stay there again, good location, very clean"
The price is SAR 563
SAR 1,224 total
includes taxes & fees
6 Jan - 7 Jan
4 bedrooms & 3 bathrooms | Entire Home For Families 🏠

KING Master En-Suite- BRAND NEW Home- Buffalo's Best Kept Secret!

9.8 out of 10, Exceptional, (34)
"I would definitely stay here again. Kelley was excellent at communicating with me and answering any questions. The house was clean and decorated very cute! They even had up a Christmas tree and decorations at Thanksgiving! Kitchen was stocked well. Beds were comfortable. The location is very convenient to so many places. It was the perfect location for us. There is a train track across the street just as an FYI. We will definitely look for this home when we need one in Buffalo again! Thanks...
KING Master En-Suite- BRAND NEW Home- Buffalo's Best Kept Secret!

KING BED- BRAND NEW FARMHOUSE II

10.0 out of 10, Exceptional, (20)
"This house was in a great location for a visit to Niagara Falls and attend a Bills game. The house was great for 4 adults and 2 small children. Decor was beautiful and was even decorated for X mas which thrilled the kids. Highly recommend "
KING BED- BRAND NEW FARMHOUSE II

No Chores, 10min downtown and 25 min Niagara falls

9.0 out of 10, Wonderful, (27)
"The property was a very convenient location, the property manager was very easy to communicate with, the beds are extremely comfortable! "
The price is SAR 338
SAR 886 total
includes taxes & fees
7 Jan - 8 Jan
No Chores, 10min downtown and 25 min Niagara falls

Newly Renovated, Charming Downtown Buffalo Home + Free Parking

9.6 out of 10, Exceptional, (47)
"My family was visiting Buffalo for our nephew's wedding. The reason we chose this house was the two bathrooms. It was a very nice stay in a beautiful home. My elderly parents stayed in the downstairs bedroom and used the downstairs bath. My family had the two bedrooms and bath upstairs. My pre-teen slept on the futon downstairs. The street was absolutely gorgeous with the fall colors. We felt safe in the neighborhood. The host was very responsive and fast with communication. I would...
Newly Renovated, Charming Downtown Buffalo Home + Free Parking

No Chores 10min downtown, 25 min to Niagara falls

9.2 out of 10, Wonderful, (13)
"Stayed for the Bills/Chiefs game. Quick 20 min uber to the stadium. 5 adults, 1 kid, 2 furry people. Plenty of space for everyone, with extra room. Beds are very comfortable. House was stocked with everything we needed (kitchen, towels, etc). Communication with owner was excellent. The neighborhood is more of an up-and-coming area which is accurately described in the listing. All in all - great landing spot for our group."
The price is SAR 338
SAR 886 total
includes taxes & fees
6 Jan - 7 Jan
No Chores 10min downtown, 25 min to Niagara falls

Entire Home 3 Bedroom 1 Bath 6 Guests - Convenient Location close to Airport

10.0 out of 10, Exceptional, (4)
"Great location and easy access to get around with a nice quiet neighborhood. Owners were very prompt with answering any questions we had."
Entire Home 3 Bedroom 1 Bath 6 Guests - Convenient Location close to Airport

Cozy 3BR/2BA 20 mins from Niagara Falls & the Buffalo Bills Stadium

10.0 out of 10, Exceptional, (21)
"A nice, quiet suburban location, which was perfect for us while visiting family and friends. The house is thoughtfully furnished. We have stayed in many VRBOs. The quality of the furnishings was among the best."
The price is SAR 620
SAR 1,461 total
includes taxes & fees
6 Jan - 7 Jan
Cozy 3BR/2BA 20 mins from Niagara Falls & the Buffalo Bills Stadium

Down Town Buffalo, 20 Minutes From The Niagara Falls

9.6 out of 10, Exceptional, (31)
"We are a family of 4, our children are 13 and 5. We loved that everyone had their own room. Our 5 year old still takes baths and there wasn’t a stopper for the tub so he couldn’t take a bath- the shower head wasn’t very high pressure but it was fine. The place was very well kept and close to everywhere we wanted to visit while in Buffalo. The house is definitely old but very clean and warm. One thing we all would have wanted was better mattresses. They all caved into the middle and weren’t easy...
The price is SAR 372
SAR 740 total
includes taxes & fees
20 Jan - 21 Jan
Down Town Buffalo, 20 Minutes From The Niagara Falls

Tonawanda Home ~ 14 Mi to Niagara Falls State Park

9.6 out of 10, Exceptional, (5)
"The property was very clean and nicely laid out in a nice neighborhood. Perfect for a stay near Niagara Falls with many things to do and see close by. "
Tonawanda Home ~ 14 Mi to Niagara Falls State Park

Bring family and friends to this beautiful, spacious, open plan log home.

10.0 out of 10, Exceptional, (5)
"We highly recommend this large home for a big family gathering. We used it for “home away from home” for our daughter’s wedding weekend. The house was very clean and well stocked. The towels and sheets were super-soft, and the mattresses were very comfortable. We would absolutely book here again! "
Bring family and friends to this beautiful, spacious, open plan log home.

5 Min Walk Bills Stadium | Private Buffalo Home

8.8 out of 10, Excellent, (9)
"Perfectly suited our needs. We were a family of 7 adults gathering in town for a wedding. We were very impressed with how clean it was. Central location walkable to the stadium. It smelled freshly painted! We had a bit of an issue with check in but the property manager helped us resolve it fairly quickly. We loved the Bills room. We all had our private spaces but could gather in the Bills room for family time. We would definitely stay here again"
5 Min Walk Bills Stadium | Private Buffalo Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Depew

On the Niagara River - River Access DOCK - POOL - HOT TUB - FIREPIT and more

10.0 out of 10, Exceptional, (143)
"Had a great weekend!! Grabbed a Buffalo Bills game, easy commute to the game from the house!! Thanks for a great stay Glen!"
On the Niagara River - River Access DOCK - POOL - HOT TUB - FIREPIT and more

Tiny Spa Cottage Retreat

9.8 out of 10, Exceptional, (79)
"Perfect place for family of four. Not one thing is lacking in this tiny house! If we come up for another Bills game (or just because) , would definitely stay here again. Thanks Theresa!!"
The price is SAR 451
SAR 683 total
includes taxes & fees
6 Jan - 7 Jan
Tiny Spa Cottage Retreat

Apartment near Water front. 20 minutes from Niagara Falls/Buffalo.

9.8 out of 10, Exceptional, (26)
"The house lies in a busy neighborhood, but was suprisingly quiet. It was a short distance from both Buffalo and Niagara Falls. The house was very nice and the doors auto lock. The only downside was even though we were upstairs, we could hear the guest downstairs moving around. It didnt bother us, but some people may not like it."
The price is SAR 255
SAR 852 total
includes taxes & fees
6 Jan - 7 Jan
Apartment near Water front. 20 minutes from Niagara Falls/Buffalo.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.