Search Vacation Homes in De Soto

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Compare 72 Vacation Homes in De Soto with updated reviews, rates, and availability.

This big old charming house Viroqua

10.0 out of 10, Exceptional, (21)
"This house was perfect for hosting my family. We had a wonderful time!"
This big old charming house Viroqua

Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

2.0 star property
10.0 out of 10, Exceptional, (2)
"We had a wonderful stay and our host was great! Wonderful property with everything we needed for a fun, stress-free stay. Three bedrooms, each with its own bath, was ideal! The great room was perfect for group, sit-down dinners and party games!"
Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

10.0 out of 10, Exceptional, (384)
"This is the second year that we have stayed at this property. Everyone loves the setting. Hosts are friendly and very helpful. Enough room so we can spread out. Kitchen is fully furnished."
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled

10.0 out of 10, Exceptional, (1)
"Good "
Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled

Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

10.0 out of 10, Exceptional, (148)
"This is our 3rd time staying here. It's a great spot to come down to see our grown kid and have everyone around. Enough to do in the house to not get bored if the weather is bad. Will be back as always. "
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Spacious Stoddard Retreat on Mississippi River!

10.0 out of 10, Exceptional, (12)
"House is as described in a beautiful location. Owners were wonderful and communication was very simple. "
Spacious Stoddard Retreat on Mississippi River!

Large Secluded Country Home Minutes from Town

10.0 out of 10, Exceptional, (65)
"Very nice and helpful host. House was clean. Plenty of room for large group. Very private neighborhood."
Large Secluded Country Home Minutes from Town

Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

9.6 out of 10, Exceptional, (55)
"Wonderful location, beautiful bathroom, relaxing. Definitely would visit again. "
The price is SAR 394
SAR 692 total
includes taxes & fees
17 Feb - 18 Feb
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

Tiny House on Upper Iowa River w/ hot tub

8.6 out of 10, Excellent, (31)
"We had a great night away in the tiny house. A couple of tight fits if you’re over 6 feet tall, but if you don’t see that coming with a tiny home, well, that’s on you. Great experience! "
The price is SAR 469
SAR 907 total
includes taxes & fees
18 Feb - 19 Feb
Tiny House on Upper Iowa River w/ hot tub

Hygge Hideaway. Pet friendly, cozy retreat & 3 minute walk to the river!

10.0 out of 10, Exceptional, (35)
"Perfect in every way. Cozy, quiet and everything you need. We will definitely go back to this little hideaway "
The price is SAR 371
SAR 471 total
includes taxes & fees
18 Feb - 19 Feb
Hygge Hideaway. Pet friendly, cozy retreat & 3 minute walk to the river!

2-bedroom vacation home just 10 minutes from Viroqua's charming downtown

10.0 out of 10, Exceptional, (54)
"We enjoyed our time at this property. Rather small seating area in the living room but it was fine for the 3 of us. Nice sleeping area on the second floor. You get the feeling of being in the woodsey outdoors but just a quick 2 mile drive into town. "
2-bedroom vacation home just 10 minutes from Viroqua's charming downtown

Ridgehaven is a peaceful, secluded cabin on 40 beautiful wooded acres

9.8 out of 10, Exceptional, (196)
"Cabin was great and would recommend to others without hesitation. Host was responsive to all my questions beforehand."
Ridgehaven is a peaceful, secluded cabin on 40 beautiful wooded acres

Nice Cape Cod home near the Mississippi River (Scenic River Inn)

9.8 out of 10, Exceptional, (121)
"This was our second winter trip here. It's a great location for us to experience winter in the Driftless area"
Nice Cape Cod home near the Mississippi River (Scenic River Inn)

Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

9.2 out of 10, Wonderful, (22)
"This was a great location for our women's weekend away. Plenty of room for the 5 of us. Property tour, hike and living quarters were as advertised. Ed was an attentive manager and addressed our requests in a timely manner. Fire ban kept us from enjoying a campfire. If you're a light sleeper - consider earplugs if on the lower level (some noise/movement heard) overnight which is expected in a shared lodge. "
Hot Tub! Cowboy Retreat! SW Wisconsin Driftless Region on UTV Route

Secluded Rustic Cabin

9.8 out of 10, Exceptional, (42)
"Cozy cabin on an absolutely beautiful secluded property. We enjoyed the hot tub, the fire pit and all the nature around us. Mt. LaCrosse ski area is about 25 minutes away where we spent 2 days skiing. "
The price is SAR 1,031
SAR 1,765 total
includes taxes & fees
20 Feb - 21 Feb
Secluded Rustic Cabin

The Honey Haven

10.0 out of 10, Exceptional, (31)
"We’ve now been to the Honey Haven twice, and both times it was a lovely visit. The place is clean and homey, and the hosts are helpful! "
The price is SAR 600
SAR 942 total
includes taxes & fees
17 Feb - 18 Feb
The Honey Haven

Eagles Landing Sleeps 15 HOT TUB

10.0 out of 10, Exceptional, (13)
"We will definitely be back!"
Eagles Landing Sleeps 15 HOT TUB

Wisconsin's Driftless Region Retreat

9.6 out of 10, Exceptional, (65)
"Wonderful again Thank you "
Wisconsin's Driftless Region Retreat

Drop Tine Ridge w/Hot Tub

Drop Tine Ridge w/Hot Tub

Luxurious home with hot tub, electric fireplace, and stunning views

2.0 star property
10.0 out of 10, Exceptional, (10)
"The property was exactly as stated in the listing. Everything was very clean. The kitchen was well-equipped with everything you need for cooking and baking. This is an excellent property if you have kids because they have everything you need including kids games, toys, pack-n-play, baby gates, kids dishes, and more! It was the small touches that made all the difference, like having extra toothpaste and toothbrushes if you forgot yours, a basket of snacks, special makeup towels, and much more! We...
Luxurious home with hot tub, electric fireplace, and stunning views
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in De Soto
Save an average of 15% on thousands of hotels when you're signed in

Other property types in De Soto

Paradise Point- Sleeps 4 HOT TUB

10.0 out of 10, Exceptional, (36)
"This place was amazing! The views were breath taking, the amenities were great, and it was the perfect spot for a getaway weekend! We will be back!"
The price is SAR 731
SAR 1,306 total
includes taxes & fees
18 Feb - 19 Feb
Paradise Point- Sleeps 4 HOT TUB

Cozy Ridge Retreat

10.0 out of 10, Exceptional, (15)
"Incredible views and wildlife! "
Cozy Ridge Retreat

Majestic View Sleeps 10-HOT TUB

10.0 out of 10, Exceptional, (37)
"Beautiful home "
Majestic View Sleeps 10-HOT TUB
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.