Find all hotels by Independent in Cayo Guillermo

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Compare rooms and suites by Independent in Cayo Guillermo with rates, reviews, and availability. Most hotels are fully refundable.